Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000015 | cellular_component | phosphopyruvate hydratase complex |
A | 0000287 | molecular_function | magnesium ion binding |
A | 0004634 | molecular_function | phosphopyruvate hydratase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005615 | cellular_component | extracellular space |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0005886 | cellular_component | plasma membrane |
A | 0006094 | biological_process | gluconeogenesis |
A | 0006096 | biological_process | glycolytic process |
A | 0016020 | cellular_component | membrane |
A | 0016829 | molecular_function | lyase activity |
A | 0046872 | molecular_function | metal ion binding |
A | 0061621 | biological_process | canonical glycolysis |
A | 0070062 | cellular_component | extracellular exosome |
B | 0000015 | cellular_component | phosphopyruvate hydratase complex |
B | 0000287 | molecular_function | magnesium ion binding |
B | 0004634 | molecular_function | phosphopyruvate hydratase activity |
B | 0005515 | molecular_function | protein binding |
B | 0005615 | cellular_component | extracellular space |
B | 0005737 | cellular_component | cytoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0005886 | cellular_component | plasma membrane |
B | 0006094 | biological_process | gluconeogenesis |
B | 0006096 | biological_process | glycolytic process |
B | 0016020 | cellular_component | membrane |
B | 0016829 | molecular_function | lyase activity |
B | 0046872 | molecular_function | metal ion binding |
B | 0061621 | biological_process | canonical glycolysis |
B | 0070062 | cellular_component | extracellular exosome |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MG A 500 |
Chain | Residue |
A | ASP245 |
A | GLU293 |
A | ASP318 |
A | HOH2267 |
A | HOH2358 |
A | HOH2506 |
site_id | AC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE PO4 A 501 |
Chain | Residue |
A | SER373 |
A | HOH2506 |
A | HOH2542 |
A | HOH2543 |
A | GLU210 |
A | LYS343 |
A | ARG372 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 502 |
Chain | Residue |
A | LYS193 |
A | THR205 |
A | VAL207 |
A | HOH2544 |
B | ASP209 |
site_id | AC4 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO A 503 |
Chain | Residue |
A | LYS202 |
A | ASP203 |
A | ALA204 |
A | THR205 |
A | ASN206 |
B | GLY160 |
B | HOH2301 |
site_id | AC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO A 504 |
Chain | Residue |
A | GLU219 |
A | ASN220 |
A | ASN221 |
A | HOH2545 |
site_id | AC6 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE EDO A 505 |
Chain | Residue |
A | GLY273 |
A | GLU274 |
A | GLY277 |
A | PHE296 |
A | THR303 |
A | SER306 |
A | PHE307 |
A | HOH2396 |
A | HOH2546 |
site_id | AC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 506 |
Chain | Residue |
A | GLU180 |
A | ARG183 |
A | ILE184 |
A | TYR236 |
A | HOH2547 |
site_id | AC8 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE EDO A 507 |
Chain | Residue |
A | LYS202 |
A | GLY310 |
A | VAL311 |
A | ASN312 |
A | EDO508 |
A | HOH2548 |
B | PHE261 |
B | LYS262 |
site_id | AC9 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE EDO A 508 |
Chain | Residue |
A | LYS202 |
A | VAL311 |
A | ASN312 |
A | EDO507 |
A | HOH2549 |
A | HOH2550 |
B | LYS262 |
B | SER263 |
B | PRO264 |
site_id | BC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO A 509 |
Chain | Residue |
A | ALA302 |
A | HOH2288 |
A | HOH2553 |
A | HOH2554 |
A | HOH2555 |
B | LEU58 |
site_id | BC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO A 510 |
Chain | Residue |
A | ASN338 |
A | HOH2462 |
A | HOH2556 |
A | HOH2557 |
site_id | BC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO A 511 |
Chain | Residue |
A | GLU21 |
A | ARG32 |
A | ASP378 |
A | HOH2558 |
site_id | BC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MG B 500 |
Chain | Residue |
B | ASP245 |
B | GLU293 |
B | ASP318 |
B | HOH2254 |
B | HOH2336 |
B | HOH2514 |
site_id | BC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE PO4 B 501 |
Chain | Residue |
B | GLU210 |
B | LYS343 |
B | ARG372 |
B | SER373 |
B | HOH2514 |
site_id | BC6 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO B 502 |
Chain | Residue |
A | GLY160 |
A | HOH2318 |
B | LYS202 |
B | ASP203 |
B | ALA204 |
B | THR205 |
B | ASN206 |
site_id | BC7 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO B 503 |
Chain | Residue |
B | GLU219 |
B | ASN220 |
B | ASN221 |
B | HOH2515 |
site_id | BC8 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO B 504 |
Chain | Residue |
B | EDO510 |
B | HOH2516 |
B | HOH2517 |
B | HOH2518 |
B | HIS191 |
B | GLY194 |
B | VAL195 |
site_id | BC9 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO B 505 |
Chain | Residue |
A | GLU10 |
A | HOH2015 |
A | HOH2017 |
B | LYS179 |
B | GLU415 |
B | HOH2264 |
site_id | CC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO B 506 |
Chain | Residue |
A | ASP209 |
B | LYS193 |
B | THR205 |
B | ASN206 |
B | HOH2519 |
site_id | CC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO B 507 |
Chain | Residue |
B | ASP142 |
B | LEU143 |
B | ILE144 |
B | ILE422 |
B | HOH2492 |
B | HOH2520 |
B | HOH2521 |
site_id | CC3 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO B 508 |
Chain | Residue |
B | GLU274 |
B | PHE307 |
B | HOH2522 |
site_id | CC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO B 509 |
Chain | Residue |
B | GLU180 |
B | ARG183 |
B | TYR236 |
B | HOH2334 |
B | HOH2523 |
site_id | CC5 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO B 510 |
Chain | Residue |
A | LEU58 |
B | GLY194 |
B | EDO504 |
Functional Information from PROSITE/UniProt
site_id | PS00164 |
Number of Residues | 14 |
Details | ENOLASE Enolase signature. LLLKvNQIGSVTES |
Chain | Residue | Details |
A | LEU340-SER353 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Proton donor => ECO:0000250 |
Chain | Residue | Details |
A | GLU210 | |
B | GLU210 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | ACT_SITE: Proton acceptor => ECO:0000250 |
Chain | Residue | Details |
A | LYS343 | |
B | LYS343 | |
site_id | SWS_FT_FI3 |
Number of Residues | 14 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | HIS158 | |
B | ASP245 | |
B | GLU293 | |
B | ASP318 | |
B | SER370 | |
B | LYS394 | |
A | GLU167 | |
A | ASP245 | |
A | GLU293 | |
A | ASP318 | |
A | SER370 | |
A | LYS394 | |
B | HIS158 | |
B | GLU167 | |
Chain | Residue | Details |
A | ALA2 | |
B | ALA2 | |
Chain | Residue | Details |
A | THR72 | |
A | THR205 | |
A | THR229 | |
B | THR72 | |
B | THR205 | |
B | THR229 | |
Chain | Residue | Details |
A | SER83 | |
A | SER157 | |
B | SER83 | |
B | SER157 | |
Chain | Residue | Details |
A | SER176 | |
A | SER263 | |
B | SER176 | |
B | SER263 | |
Chain | Residue | Details |
A | TYR236 | |
B | TYR236 | |