2XSW

Crystal structure of human INPP5E

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004445	molecular_function	inositol-polyphosphate 5-phosphatase activity
A	0016791	molecular_function	phosphatase activity
A	0046856	biological_process	phosphatidylinositol dephosphorylation
B	0004445	molecular_function	inositol-polyphosphate 5-phosphatase activity
B	0016791	molecular_function	phosphatase activity
B	0046856	biological_process	phosphatidylinositol dephosphorylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 1625

Chain	Residue
A	LYS404
A	SER427

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site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL A 1626

Chain	Residue
A	HIS584
A	HOH2208
A	HOH2209
A	GLU340
A	HIS424
A	SER427
A	ASP477
A	ASN479
A	TYR534
A	THR555

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 1627

Chain	Residue
A	SER391
A	HOH2061
A	HOH2062
B	ARG441

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 1628

Chain	Residue
A	GLU340
A	HIS424
A	HOH2072
A	HOH2087

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site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE GOL A 1629

Chain	Residue
A	ARG621

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site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL B 1624

Chain	Residue
B	VAL398
B	LYS404
B	SER427

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site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 1625

Chain	Residue
B	GLU340
B	HIS424

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site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL B 1626

Chain	Residue
B	GLU340
B	HIS424
B	SER427
B	ASP477
B	ASN479
B	TYR534
B	HIS584

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