Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004177 | molecular_function | aminopeptidase activity |
A | 0004301 | molecular_function | epoxide hydrolase activity |
A | 0005634 | cellular_component | nucleus |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006508 | biological_process | proteolysis |
A | 0008237 | molecular_function | metallopeptidase activity |
A | 0008270 | molecular_function | zinc ion binding |
A | 0030163 | biological_process | protein catabolic process |
A | 0043171 | biological_process | peptide catabolic process |
A | 0044255 | biological_process | cellular lipid metabolic process |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE BU3 A 1672 |
Chain | Residue |
A | GLN173 |
A | THR174 |
A | GLY623 |
A | THR656 |
A | HOH2464 |
site_id | AC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE ZN A 1673 |
Chain | Residue |
A | HIS340 |
A | HIS344 |
A | GLU363 |
site_id | AC3 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE 15P A 1674 |
Chain | Residue |
A | VAL217 |
A | PHE218 |
A | GLY220 |
A | ARG222 |
A | ASP229 |
A | TYR233 |
A | PHE235 |
A | TYR265 |
A | MET320 |
A | HOH2473 |
A | HOH2474 |
A | VAL216 |
Functional Information from PROSITE/UniProt
site_id | PS00142 |
Number of Residues | 10 |
Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VIAHELAHSW |
Chain | Residue | Details |
A | VAL337-TRP346 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Proton acceptor |
Chain | Residue | Details |
A | GLU341 | |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | ACT_SITE: Proton donor |
Chain | Residue | Details |
A | TYR429 | |
site_id | SWS_FT_FI3 |
Number of Residues | 5 |
Details | BINDING: |
Chain | Residue | Details |
A | GLN184 | |
A | PRO311 | |
A | HIS340 | |
A | HIS344 | |
A | GLU363 | |