2XOF

Ribonucleotide reductase Y122NO2Y modified R2 subunit of E. coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004748	molecular_function	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
A	0005506	molecular_function	iron ion binding
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005971	cellular_component	ribonucleoside-diphosphate reductase complex
A	0009185	biological_process	ribonucleoside diphosphate metabolic process
A	0009263	biological_process	deoxyribonucleotide biosynthetic process
A	0009265	biological_process	2'-deoxyribonucleotide biosynthetic process
A	0015949	biological_process	nucleobase-containing small molecule interconversion
A	0016491	molecular_function	oxidoreductase activity
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
B	0004748	molecular_function	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
B	0005506	molecular_function	iron ion binding
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005971	cellular_component	ribonucleoside-diphosphate reductase complex
B	0009185	biological_process	ribonucleoside diphosphate metabolic process
B	0009263	biological_process	deoxyribonucleotide biosynthetic process
B	0009265	biological_process	2'-deoxyribonucleotide biosynthetic process
B	0015949	biological_process	nucleobase-containing small molecule interconversion
B	0016491	molecular_function	oxidoreductase activity
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE FEO A 400

Chain	Residue
A	ASP84
A	GLU115
A	HIS118
A	GLU204
A	GLU238
A	HIS241
A	HOH2136
A	HOH2190

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site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE FEO B 400

Chain	Residue
B	GLU115
B	HIS118
B	GLU204
B	GLU238
B	HIS241
B	HOH2063
B	HOH2117
B	ASP84

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Functional Information from PROSITE/UniProt

site_id	PS00368
Number of Residues	17
Details	RIBORED_SMALL Ribonucleotide reductase small subunit signature. SEt.IHSrSYthIirnIV

Chain	Residue	Details
A	SER114-VAL130

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE:

Chain	Residue	Details
A	NIY122
B	NIY122

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site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING:

Chain	Residue	Details
A	ASP84
A	GLU238
A	HIS241
B	ASP84
B	GLU115
B	HIS118
B	GLU204
B	GLU238
B	HIS241
A	GLU115
A	HIS118
A	GLU204

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	2
Details	M-CSA 918

Chain	Residue	Details
A	NIY122	pi-pi interaction, single electron relay
A	ASP237

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site_id	MCSA2
Number of Residues	2
Details	M-CSA 918

Chain	Residue	Details
B	NIY122	pi-pi interaction, single electron relay
B	ASP237

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