2XNY

A fragment of streptococcal M1 protein in complex with human fibrinogen

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005102	molecular_function	signaling receptor binding
A	0005577	cellular_component	fibrinogen complex
A	0007596	biological_process	blood coagulation
A	0030168	biological_process	platelet activation
A	0051258	biological_process	protein polymerization
B	0005102	molecular_function	signaling receptor binding
B	0005577	cellular_component	fibrinogen complex
B	0007596	biological_process	blood coagulation
B	0030168	biological_process	platelet activation
B	0051258	biological_process	protein polymerization
C	0005102	molecular_function	signaling receptor binding
C	0005577	cellular_component	fibrinogen complex
C	0007596	biological_process	blood coagulation
C	0030168	biological_process	platelet activation
C	0051258	biological_process	protein polymerization
D	0005102	molecular_function	signaling receptor binding
D	0005577	cellular_component	fibrinogen complex
D	0007596	biological_process	blood coagulation
D	0030168	biological_process	platelet activation
D	0051258	biological_process	protein polymerization
E	0005102	molecular_function	signaling receptor binding
E	0005577	cellular_component	fibrinogen complex
E	0007596	biological_process	blood coagulation
E	0030168	biological_process	platelet activation
E	0051258	biological_process	protein polymerization
F	0005102	molecular_function	signaling receptor binding
F	0005577	cellular_component	fibrinogen complex
F	0007596	biological_process	blood coagulation
F	0030168	biological_process	platelet activation
F	0051258	biological_process	protein polymerization

Functional Information from PROSITE/UniProt

site_id	PS00514
Number of Residues	13
Details	FIBRINOGEN_C_1 Fibrinogen C-terminal domain signature. WWYnrChaAnpNG

Chain	Residue	Details
B	TRP402-GLY414
C	TRP334-GLY346

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1004
Details	Domain: {"description":"Fibrinogen C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00739","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"10074346","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16263699","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9628725","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"book","publicationDate":"1980","firstPage":"51","lastPage":"56","publisher":"Pergamon Press","address":"Oxford","bookName":"Protides of the biological fluids, Proc. 28th colloquium","title":"Human fibrinogen: sequence, sulfur bridges, glycosylation and some structural variants.","editors":["Peeters H."],"authors":["Henschen A.","Lottspeich F.","Southan C.","Topfer-Petersen E."]}}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10074346","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19296670","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9016719","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9207064","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9333233","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9628725","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1FID","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; in variant Asahi"}

Chain

Residue

Details

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