2XM3

Deinococcus radiodurans ISDra2 Transposase Left end DNA complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004803	molecular_function	transposase activity
A	0006310	biological_process	DNA recombination
A	0006313	biological_process	DNA transposition
A	0016787	molecular_function	hydrolase activity
A	0032196	biological_process	transposition
A	0046872	molecular_function	metal ion binding
B	0003677	molecular_function	DNA binding
B	0004518	molecular_function	nuclease activity
B	0004519	molecular_function	endonuclease activity
B	0004803	molecular_function	transposase activity
B	0006310	biological_process	DNA recombination
B	0006313	biological_process	DNA transposition
B	0016787	molecular_function	hydrolase activity
B	0032196	biological_process	transposition
B	0046872	molecular_function	metal ion binding
C	0003677	molecular_function	DNA binding
C	0004518	molecular_function	nuclease activity
C	0004519	molecular_function	endonuclease activity
C	0004803	molecular_function	transposase activity
C	0006310	biological_process	DNA recombination
C	0006313	biological_process	DNA transposition
C	0016787	molecular_function	hydrolase activity
C	0032196	biological_process	transposition
C	0046872	molecular_function	metal ion binding
D	0003677	molecular_function	DNA binding
D	0004518	molecular_function	nuclease activity
D	0004519	molecular_function	endonuclease activity
D	0004803	molecular_function	transposase activity
D	0006310	biological_process	DNA recombination
D	0006313	biological_process	DNA transposition
D	0016787	molecular_function	hydrolase activity
D	0032196	biological_process	transposition
D	0046872	molecular_function	metal ion binding
E	0003677	molecular_function	DNA binding
E	0004518	molecular_function	nuclease activity
E	0004519	molecular_function	endonuclease activity
E	0004803	molecular_function	transposase activity
E	0006310	biological_process	DNA recombination
E	0006313	biological_process	DNA transposition
E	0016787	molecular_function	hydrolase activity
E	0032196	biological_process	transposition
E	0046872	molecular_function	metal ion binding
F	0003677	molecular_function	DNA binding
F	0004518	molecular_function	nuclease activity
F	0004519	molecular_function	endonuclease activity
F	0004803	molecular_function	transposase activity
F	0006310	biological_process	DNA recombination
F	0006313	biological_process	DNA transposition
F	0016787	molecular_function	hydrolase activity
F	0032196	biological_process	transposition
F	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ACT B 1135

Chain	Residue
B	GLU62
B	VAL63

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG E 1135

Chain	Residue
E	PRO114
E	HOH2034
O	DC31
O	HOH2017
O	HOH2019
O	HOH2020

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG F 1135

Chain	Residue
F	HOH2023
Q	DC31
Q	HOH2018
Q	HOH2019
Q	HOH2020
F	PRO114

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL G 1038

Chain	Residue
A	CYS27
A	CYS117
A	HOH2013
G	DC15
G	DA16
G	HOH2035
H	DT5

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG G 1039

Chain	Residue
A	PRO114
B	HOH2003
G	DC31
G	HOH2024
G	HOH2026
G	HOH2028

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG G 1114

Chain	Residue
G	HOH2012
G	HOH2013
G	HOH2030
G	HOH2032
G	HOH2033
G	HOH2034

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG I 1038

Chain	Residue
B	PRO114
B	HOH2045
I	DC31
I	HOH2026
I	HOH2029
I	HOH2031

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG I 1116

Chain	Residue
I	HOH2010
I	HOH2013
I	HOH2035
I	HOH2037
I	HOH2038
I	HOH2040

---

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL J 1006

Chain	Residue
B	CYS27
B	CYS117
I	DC15
I	DA16
J	DT5
J	HOH2007
J	HOH2008

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG K 1038

Chain	Residue
C	PRO114
C	HOH2049
K	DC31
K	HOH2030
K	HOH2033
K	HOH2035

---

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG K 1039

Chain	Residue
K	HOH2003
K	HOH2004
K	HOH2039
K	HOH2040
K	HOH2043
K	HOH2045

---

site_id	BC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL L 1006

Chain	Residue
C	CYS27
C	CYS117
C	HOH2005
K	DC15
K	DA16
L	DT5
L	HOH2004

---

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG M 1038

Chain	Residue
D	PRO114
D	HOH2040
M	DC31
M	HOH2018
M	HOH2019
M	HOH2023

---

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG M 1121

Chain	Residue
M	HOH2008
M	HOH2010
M	HOH2026
M	HOH2027
M	HOH2028
M	HOH2029

---

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG O 1112

Chain	Residue
O	HOH2003
O	HOH2009
O	HOH2010
O	HOH2021
O	HOH2022
O	HOH2023

---

site_id	BC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL P 1007

Chain	Residue
E	CYS27
E	CYS117
E	HOH2011
F	TYR132
O	DC15
O	DA16
P	DT5

---

site_id	BC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG Q 1111

Chain	Residue
Q	HOH2021
Q	HOH2023
Q	HOH2024
Q	HOH2003
Q	HOH2004
Q	HOH2015

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	36
Details	Region: {"description":"Mobile alpha helix","evidences":[{"source":"PubMed","id":"20890269","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"20890269","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	13
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20890269","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Site: {"description":"Critical for recognizing and stabilizing G:T mismatch in DNA substrate","evidences":[{"source":"PubMed","id":"20890269","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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