2XKO

Crystal structure of the complex of NtcA with its transcriptional co- activator PipX

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005515	molecular_function	protein binding
A	0005829	cellular_component	cytosol
A	0006355	biological_process	regulation of DNA-templated transcription
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0005515	molecular_function	protein binding
B	0005829	cellular_component	cytosol
B	0006355	biological_process	regulation of DNA-templated transcription
C	0005515	molecular_function	protein binding
D	0005515	molecular_function	protein binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE AKG A 1223

Chain	Residue
A	LEU53
B	GLU133
A	PHE74
A	GLY75
A	VAL76
A	LEU77
A	ARG87
A	ARG128
A	HOH2037
B	ILE129

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site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE AKG B 1223

Chain	Residue
A	ILE129
A	LEU130
A	GLU133
B	LEU53
B	PHE74
B	GLY75
B	VAL76
B	LEU77
B	ARG87
B	ARG128
B	HOH2034

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Functional Information from PROSITE/UniProt

site_id	PS00042
Number of Residues	24
Details	HTH_CRP_1 Crp-type HTH domain signature. LSHqaIAeAIGsTrvTv.TRlLgdL

Chain	Residue	Details
A	LEU173-LEU196

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	146
Details	Domain: {"description":"HTH crp-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00387","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	38
Details	DNA binding: {"description":"H-T-H motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00387","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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