Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004601 | molecular_function | peroxidase activity |
A | 0006979 | biological_process | response to oxidative stress |
A | 0020037 | molecular_function | heme binding |
A | 0034599 | biological_process | cellular response to oxidative stress |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE MPD A 1295 |
Chain | Residue |
A | LYS59 |
A | HIS60 |
A | ASP254 |
A | ASP256 |
A | LYS257 |
A | LYS260 |
A | HOH2471 |
A | HOH2671 |
A | HOH2672 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MRD A 1296 |
Chain | Residue |
A | ASP148 |
A | SER185 |
A | TYR187 |
A | ASN220 |
A | MPD1300 |
A | HOH2673 |
site_id | AC3 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE MPD A 1297 |
Chain | Residue |
A | LYS12 |
A | GLU188 |
A | HOH2498 |
A | HOH2547 |
A | HOH2549 |
A | HOH2564 |
A | HOH2674 |
site_id | AC4 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MRD A 1298 |
Chain | Residue |
A | GLN240 |
A | HOH2675 |
site_id | AC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MRD A 1299 |
Chain | Residue |
A | LYS264 |
A | HOH2286 |
A | HOH2348 |
A | HOH2628 |
A | HOH2678 |
site_id | AC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE MPD A 1300 |
Chain | Residue |
A | SER185 |
A | MRD1296 |
A | HOH2679 |
site_id | AC7 |
Number of Residues | 24 |
Details | BINDING SITE FOR RESIDUE HEM A 1301 |
Chain | Residue |
A | PRO44 |
A | VAL45 |
A | ARG48 |
A | TRP51 |
A | PRO145 |
A | ASP146 |
A | ALA147 |
A | LEU171 |
A | ALA174 |
A | HIS175 |
A | LEU177 |
A | GLY178 |
A | LYS179 |
A | THR180 |
A | HIS181 |
A | ASN184 |
A | SER185 |
A | TRP191 |
A | LEU232 |
A | THR234 |
A | HOH2188 |
A | HOH2681 |
A | HOH2682 |
A | HOH2683 |
site_id | AC8 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE PO4 A 1302 |
Chain | Residue |
A | TYR36 |
A | ASP37 |
A | HOH2684 |
Functional Information from PROSITE/UniProt
site_id | PS00435 |
Number of Residues | 11 |
Details | PEROXIDASE_1 Peroxidases proximal heme-ligand signature. EVVALMGAHAL |
Chain | Residue | Details |
A | GLU167-LEU177 | |
site_id | PS00436 |
Number of Residues | 12 |
Details | PEROXIDASE_2 Peroxidases active site signature. GPvlVRLaWHTS |
Chain | Residue | Details |
A | GLY43-SER54 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Proton acceptor |
Chain | Residue | Details |
A | HIS52 | |
Chain | Residue | Details |
A | TRP191 | |
Chain | Residue | Details |
A | HIS175 | |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | SITE: Transition state stabilizer |
Chain | Residue | Details |
A | ARG48 | |
Chain | Residue | Details |
A | TYR153 | |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 3 |
Details | M-CSA 709 |
Chain | Residue | Details |
A | ARG48 | electrostatic stabiliser |
A | HIS52 | electrostatic stabiliser, proton acceptor, proton donor |
A | TRP191 | single electron acceptor, single electron donor |