2XIB
CRYSTAL STRUCTURE OF AN ALPHA-L-FUCOSIDASE GH29 FROM BACTEROIDES THETAIOTAOMICRON IN COMPLEX WITH DEOXYFUCONOJIRIMYCIN
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004560 | molecular_function | alpha-L-fucosidase activity |
| A | 0005764 | cellular_component | lysosome |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006004 | biological_process | fucose metabolic process |
| A | 0016139 | biological_process | glycoside catabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0004560 | molecular_function | alpha-L-fucosidase activity |
| B | 0005764 | cellular_component | lysosome |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006004 | biological_process | fucose metabolic process |
| B | 0016139 | biological_process | glycoside catabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0004560 | molecular_function | alpha-L-fucosidase activity |
| C | 0005764 | cellular_component | lysosome |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0006004 | biological_process | fucose metabolic process |
| C | 0016139 | biological_process | glycoside catabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| D | 0004560 | molecular_function | alpha-L-fucosidase activity |
| D | 0005764 | cellular_component | lysosome |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0006004 | biological_process | fucose metabolic process |
| D | 0016139 | biological_process | glycoside catabolic process |
| D | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE DFU A 1472 |
| Chain | Residue |
| A | HIS66 |
| A | GLU87 |
| A | TRP88 |
| A | HIS135 |
| A | HIS136 |
| A | TYR178 |
| A | ASP229 |
| A | GLU288 |
| A | TRP316 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE DFU B 1472 |
| Chain | Residue |
| B | HIS66 |
| B | GLU87 |
| B | TRP88 |
| B | HIS135 |
| B | HIS136 |
| B | TYR178 |
| B | ASP229 |
| B | GLU288 |
| B | TRP316 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE DFU C 1472 |
| Chain | Residue |
| C | HIS66 |
| C | GLU87 |
| C | TRP88 |
| C | HIS135 |
| C | HIS136 |
| C | TYR178 |
| C | ASP229 |
| C | GLU288 |
| C | TRP316 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE DFU D 1472 |
| Chain | Residue |
| D | HIS66 |
| D | GLU87 |
| D | TRP88 |
| D | HIS135 |
| D | HIS136 |
| D | TYR178 |
| D | ASP229 |
| D | GLU288 |
| D | TRP316 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1473 |
| Chain | Residue |
| C | TRP232 |
| C | ARG262 |
| C | ARG271 |
| C | HIS272 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1473 |
| Chain | Residue |
| A | ASN169 |
| A | ASP174 |
| A | HOH2162 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1473 |
| Chain | Residue |
| D | TRP232 |
| D | ARG262 |
| D | ARG271 |
| D | HIS272 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1474 |
| Chain | Residue |
| A | ARG262 |
| A | ARG271 |
| A | HIS272 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1473 |
| Chain | Residue |
| B | TRP232 |
| B | ARG262 |
| B | ARG271 |
| B | HIS272 |
| B | HOH2114 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE TRS D 1474 |
| Chain | Residue |
| C | GLN392 |
| C | ASP393 |
| C | ILE419 |
| D | ASP335 |
| D | ASN411 |
| D | GOL1475 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL D 1475 |
| Chain | Residue |
| C | SER415 |
| C | ARG417 |
| C | ILE419 |
| D | ASP335 |
| D | PHE410 |
| D | ASN411 |
| D | TRS1474 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 1474 |
| Chain | Residue |
| A | ASP335 |
| A | PHE410 |
| A | ASN411 |
| B | PRO413 |
| B | TYR414 |
| B | SER415 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL C 1474 |
| Chain | Residue |
| C | ALA63 |
| C | TRP117 |
| C | ALA121 |
| C | MET124 |
| C | THR126 |
| C | TYR168 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL B 1475 |
| Chain | Residue |
| B | GLY172 |
| B | ASP174 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 1475 |
| Chain | Residue |
| A | SER415 |
| A | ARG417 |
| A | ILE419 |
| A | HOH2163 |
| B | ASP335 |
