2XHY
Crystal Structure of E.coli BglA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0005829 | cellular_component | cytosol |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0008422 | molecular_function | beta-glucosidase activity |
| A | 0008706 | molecular_function | 6-phospho-beta-glucosidase activity |
| A | 0015926 | molecular_function | glucosidase activity |
| A | 0016052 | biological_process | carbohydrate catabolic process |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0103047 | molecular_function | methyl beta-D-glucoside 6-phosphate glucohydrolase activity |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0005829 | cellular_component | cytosol |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0008422 | molecular_function | beta-glucosidase activity |
| B | 0008706 | molecular_function | 6-phospho-beta-glucosidase activity |
| B | 0015926 | molecular_function | glucosidase activity |
| B | 0016052 | biological_process | carbohydrate catabolic process |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0103047 | molecular_function | methyl beta-D-glucoside 6-phosphate glucohydrolase activity |
| C | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| C | 0005829 | cellular_component | cytosol |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0008422 | molecular_function | beta-glucosidase activity |
| C | 0008706 | molecular_function | 6-phospho-beta-glucosidase activity |
| C | 0015926 | molecular_function | glucosidase activity |
| C | 0016052 | biological_process | carbohydrate catabolic process |
| C | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| C | 0103047 | molecular_function | methyl beta-D-glucoside 6-phosphate glucohydrolase activity |
| D | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| D | 0005829 | cellular_component | cytosol |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0008422 | molecular_function | beta-glucosidase activity |
| D | 0008706 | molecular_function | 6-phospho-beta-glucosidase activity |
| D | 0015926 | molecular_function | glucosidase activity |
| D | 0016052 | biological_process | carbohydrate catabolic process |
| D | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| D | 0103047 | molecular_function | methyl beta-D-glucoside 6-phosphate glucohydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE BR A 1480 |
| Chain | Residue |
| A | LYS53 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1481 |
| Chain | Residue |
| A | HOH2370 |
| A | TRP351 |
| A | SER432 |
| A | PHE433 |
| A | THR434 |
| A | LYS440 |
| A | TYR442 |
| A | HOH2368 |
| A | HOH2369 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR A 1482 |
| Chain | Residue |
| A | SER439 |
| A | HIS450 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR A 1483 |
| Chain | Residue |
| A | GLY299 |
| A | LEU301 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE BR B 1481 |
| Chain | Residue |
| B | ARG231 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE BR B 1482 |
| Chain | Residue |
| B | LYS53 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR B 1483 |
| Chain | Residue |
| B | PRO190 |
| B | LEU191 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1484 |
| Chain | Residue |
| B | TRP351 |
| B | SER432 |
| B | PHE433 |
| B | THR434 |
| B | LYS440 |
| B | TYR442 |
| B | HOH2354 |
| B | HOH2395 |
| B | HOH2396 |
| B | HOH2397 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1485 |
| Chain | Residue |
| B | LEU247 |
| B | SER263 |
| B | GLU336 |
| B | HOH2398 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BR B 1486 |
| Chain | Residue |
| B | GLY299 |
| B | ASP300 |
| B | LEU301 |
| B | HOH2281 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BR B 1487 |
| Chain | Residue |
| B | ASN206 |
| B | GLU208 |
| B | GLU209 |
| B | PHE292 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR C 1480 |
| Chain | Residue |
| C | SER439 |
| C | HIS450 |
| site_id | BC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE BR C 1481 |
| Chain | Residue |
| C | ALA104 |
| site_id | BC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1482 |
| Chain | Residue |
| C | TRP351 |
| C | SER432 |
| C | PHE433 |
| C | THR434 |
| C | LYS440 |
| C | TYR442 |
| C | HOH2431 |
| C | HOH2477 |
| C | HOH2478 |
| C | HOH2479 |
| site_id | BC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR C 1483 |
| Chain | Residue |
| C | LYS53 |
| D | LYS295 |
| site_id | BC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR D 1480 |
| Chain | Residue |
| D | LYS410 |
| D | TYR414 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR D 1481 |
| Chain | Residue |
| D | GLU336 |
| D | HOH2292 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BR D 1482 |
| Chain | Residue |
| D | SER439 |
| D | HIS450 |
| D | ASP451 |
| D | HOH2367 |
| site_id | CC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE BR D 1483 |
| Chain | Residue |
| D | GLN144 |
| site_id | CC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR D 1484 |
| Chain | Residue |
| D | PRO190 |
| D | LEU191 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BR D 1485 |
| Chain | Residue |
| D | ASN206 |
| D | GLU208 |
| D | GLU209 |
| D | HOH2206 |
| site_id | CC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1486 |
| Chain | Residue |
| D | TRP351 |
| D | PHE433 |
| D | THR434 |
| D | LYS440 |
| D | TYR442 |
| D | HOH2398 |
| D | HOH2399 |
| D | HOH2400 |
| site_id | CC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BR D 1487 |
| Chain | Residue |
| D | GLY299 |
| D | LEU301 |
| D | HOH2274 |
Functional Information from PROSITE/UniProt
| site_id | PS00572 |
| Number of Residues | 9 |
| Details | GLYCOSYL_HYDROL_F1_1 Glycosyl hydrolases family 1 active site. LFIVENGFG |
| Chain | Residue | Details |
| A | LEU373-GLY381 |
| site_id | PS00653 |
| Number of Residues | 15 |
| Details | GLYCOSYL_HYDROL_F1_2 Glycosyl hydrolases family 1 N-terminal signature. FlWGgAvAAHQvEgG |
| Chain | Residue | Details |
| A | PHE12-GLY26 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton donor => ECO:0000255 |
| Chain | Residue | Details |
| A | GLU180 | |
| B | GLU180 | |
| C | GLU180 | |
| D | GLU180 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | ACT_SITE: Nucleophile => ECO:0000255|PROSITE-ProRule:PRU10055 |
| Chain | Residue | Details |
| A | GLU377 | |
| B | GLU377 | |
| C | GLU377 | |
| D | GLU377 |
