2XH9
Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008800 | molecular_function | beta-lactamase activity |
| A | 0017001 | biological_process | antibiotic catabolic process |
| A | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
| A | 0046677 | biological_process | response to antibiotic |
| B | 0008800 | molecular_function | beta-lactamase activity |
| B | 0017001 | biological_process | antibiotic catabolic process |
| B | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
| B | 0046677 | biological_process | response to antibiotic |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE J01 A 1436 |
| Chain | Residue |
| A | HIS84 |
| A | HOH2312 |
| A | TRP91 |
| A | VAL93 |
| A | LEU362 |
| A | ARG418 |
| A | GLY419 |
| A | ALA422 |
| A | LYS423 |
| A | HOH2311 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE J01 A 1437 |
| Chain | Residue |
| A | LYS89 |
| A | THR209 |
| A | SER234 |
| A | TYR359 |
| A | ALA376 |
| A | ALA378 |
| A | PHE385 |
| A | ASP413 |
| A | ARG418 |
| A | HOH2141 |
| A | HOH2313 |
| A | HOH2314 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE J01 B 1436 |
| Chain | Residue |
| B | HIS84 |
| B | VAL93 |
| B | LEU362 |
| B | ARG418 |
| B | GLY419 |
| B | ALA422 |
| B | LYS423 |
| B | HOH2075 |
| B | HOH2324 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE J01 B 1437 |
| Chain | Residue |
| B | LYS89 |
| B | SER173 |
| B | THR209 |
| B | SER234 |
| B | TYR359 |
| B | ALA376 |
| B | ALA378 |
| B | ASP413 |
| B | ARG418 |
| B | HOH2159 |
| B | HOH2285 |
| B | HOH2325 |
