2XCP

TERNARY COMPLEX OF SULFOLOBUS SOLFATARICUS DPO4 DNA POLYMERASE, 7,8- DIHYDRO-8-OXODEOXYGUANINE MODIFIED DNA AND dCTP - MAGNESIUM FORM

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003677	molecular_function	DNA binding
A	0003684	molecular_function	damaged DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005737	cellular_component	cytoplasm
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006281	biological_process	DNA repair
A	0006974	biological_process	DNA damage response
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0034061	molecular_function	DNA polymerase activity
A	0042276	biological_process	error-prone translesion synthesis
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0003677	molecular_function	DNA binding
B	0003684	molecular_function	damaged DNA binding
B	0003887	molecular_function	DNA-directed DNA polymerase activity
B	0005737	cellular_component	cytoplasm
B	0006260	biological_process	DNA replication
B	0006261	biological_process	DNA-templated DNA replication
B	0006281	biological_process	DNA repair
B	0006974	biological_process	DNA damage response
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0034061	molecular_function	DNA polymerase activity
B	0042276	biological_process	error-prone translesion synthesis
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 1000

Chain	Residue
A	ASP7
A	PHE8
A	ASP105
A	HOH2120
A	DCP5000

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B 1001

Chain	Residue
B	DCP5000
A	HOH2130
B	ASP7
B	PHE8
B	ASP105

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 1002

Chain	Residue
A	ASP294
A	HOH2100
P	DG9
P	HOH2014

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 1003

Chain	Residue
B	ASP294
B	HOH2085
E	DG8
E	DG9

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 1004

Chain	Residue
A	ASP7
A	ASP105
A	GLU106
A	HOH2120
A	HOH2121
A	DCP5000

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 1005

Chain	Residue
A	HOH2126
A	HOH2130
B	ASP7
B	ASP105
B	GLU106
B	DCP5000

---

site_id	AC7
Number of Residues	23
Details	BINDING SITE FOR RESIDUE DCP A 5000

Chain	Residue
A	ASP7
A	PHE8
A	ASP9
A	TYR10
A	PHE11
A	TYR12
A	THR45
A	TYR48
A	ARG51
A	ILE104
A	ASP105
A	LYS159
A	MG1000
A	MG1004
A	HOH2117
A	HOH2118
A	HOH2119
A	HOH2120
A	HOH2121
A	HOH2122
A	HOH2123
P	DOC13
T	8OG5

---

site_id	AC8
Number of Residues	24
Details	BINDING SITE FOR RESIDUE DCP B 5000

Chain	Residue
A	HOH2124
A	HOH2126
A	HOH2128
A	HOH2129
A	HOH2130
A	HOH2131
A	HOH2132
A	HOH2133
B	ASP7
B	PHE8
B	ASP9
B	TYR10
B	PHE11
B	TYR12
B	ALA44
B	THR45
B	TYR48
B	ARG51
B	ASP105
B	LYS159
B	MG1001
B	MG1005
E	DOC13
F	8OG5

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	368
Details	Domain: {"description":"UmuC"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Site: {"description":"Substrate discrimination"}

Chain

Residue

Details

---