2X9P

X-ray structure of the substrate-free cytochrome P450 PimD - a polyene macrolide antibiotic pimaricin epoxidase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004497	molecular_function	monooxygenase activity
A	0005506	molecular_function	iron ion binding
A	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
A	0020037	molecular_function	heme binding
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	25
Details	BINDING SITE FOR RESIDUE HEM A 1398

Chain	Residue
A	ARG65
A	VAL239
A	LEU285
A	PRO286
A	ARG288
A	LEU311
A	THR338
A	PHE339
A	GLY340
A	ILE343
A	TRP344
A	HIS98
A	HIS345
A	CYS346
A	GLY348
A	ALA352
A	HOH2103
A	HOH2175
A	ARG102
A	LEU105
A	PHE109
A	LEU154
A	ALA234
A	GLY235
A	SER238

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 1399

Chain	Residue
A	ASP30
A	ARG50
A	HOH2176

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 1400

Chain	Residue
A	HIS253
A	PRO254
A	ASP255
A	GLN256

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 1401

Chain	Residue
A	HIS345
A	ARG353
A	HOH2177

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