2X76

The crystal structure of PhaZ7 at atomic (1.2 Angstrom) resolution reveals details of the active site and suggests a substrate binding mode

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016042	biological_process	lipid catabolic process
A	0016298	molecular_function	lipase activity
A	0016787	molecular_function	hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 1360

Chain	Residue
A	HOH2444

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD A 1343

Chain	Residue
A	SER7
A	SER35
A	NA1357

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 1344

Chain	Residue
A	HOH2354
A	HOH2358

---

site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 1345

Chain	Residue
A	GLY25

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 1346

Chain	Residue
A	GLY27

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IOD A 1347

Chain	Residue
A	LYS157
A	ALA341
A	HOH2277
A	ARG156

---

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 1348

Chain	Residue
A	ASN6
A	HOH2011

---

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 1359

Chain	Residue
A	THR41
A	HOH2446

---

site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 1349

Chain	Residue
A	GLY205

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 1351

Chain	Residue
A	MET291
A	HOH2210

---

site_id	BC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 1352

Chain	Residue
A	ASN294

---

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 1353

Chain	Residue
A	GLY65
A	GLY67

---

site_id	BC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 1354

Chain	Residue
A	ASP84
A	HOH2079

---

site_id	BC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 1355

Chain	Residue
A	TYR204

---

site_id	BC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA A 1356

Chain	Residue
A	TYR204
A	HOH2418

---

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA A 1357

Chain	Residue
A	THR5
A	GLY20
A	SER35
A	IOD1343
A	HOH2017

---

site_id	BC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 1358

Chain	Residue
A	THR37
A	ALA38
A	THR125
A	GLY126
A	LYS127
A	THR324
A	HOH2467
A	HOH2469
A	HOH2470

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