2X5Z
Crystal structure of T. maritima GDP-mannose pyrophosphorylase in complex with GDP-mannose.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004475 | molecular_function | mannose-1-phosphate guanylyltransferase (GTP) activity |
| A | 0005525 | molecular_function | GTP binding |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009298 | biological_process | GDP-mannose biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004475 | molecular_function | mannose-1-phosphate guanylyltransferase (GTP) activity |
| B | 0005525 | molecular_function | GTP binding |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009298 | biological_process | GDP-mannose biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE GDD A 601 |
| Chain | Residue |
| A | LEU7 |
| A | PRO107 |
| A | ALA108 |
| A | ASP109 |
| A | HIS110 |
| A | TYR149 |
| A | GLY150 |
| A | GLU170 |
| A | LYS171 |
| A | ASN189 |
| A | SER190 |
| A | GLY9 |
| A | GLY191 |
| A | ASP239 |
| A | TRP258 |
| A | ASP260 |
| A | MG602 |
| A | HOH2022 |
| A | HOH2023 |
| A | GLY10 |
| A | VAL56 |
| A | GLU80 |
| A | LYS83 |
| A | LYS84 |
| A | ASN85 |
| A | THR86 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 602 |
| Chain | Residue |
| A | ASP109 |
| A | ASP260 |
| A | GDD601 |
| A | HOH2016 |
| A | HOH2023 |
| site_id | AC3 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE GDD B 601 |
| Chain | Residue |
| B | LEU7 |
| B | ALA8 |
| B | GLY9 |
| B | GLY10 |
| B | VAL56 |
| B | GLU80 |
| B | LYS83 |
| B | LYS84 |
| B | ASN85 |
| B | THR86 |
| B | PRO107 |
| B | ALA108 |
| B | ASP109 |
| B | HIS110 |
| B | TYR149 |
| B | GLY150 |
| B | GLU170 |
| B | LYS171 |
| B | ASN189 |
| B | SER190 |
| B | GLY191 |
| B | ASP239 |
