2X5X

The crystal structure of PhaZ7 at atomic (1.2 Angstrom) resolution reveals details of the active site and suggests a substrate binding mode

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016042	biological_process	lipid catabolic process
A	0016298	molecular_function	lipase activity
A	0016787	molecular_function	hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD A 1343

Chain	Residue
A	SER7
A	SER35
A	NA1357

---

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 1345

Chain	Residue
A	GLY25
A	HOH2032

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 1346

Chain	Residue
A	GLY27
A	HOH2079

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IOD A 1347

Chain	Residue
A	ALA341
A	HOH2525
A	ARG156
A	LYS157

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 1348

Chain	Residue
A	ASN6
A	HOH2008

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO2 A 1349

Chain	Residue
A	ASN49
A	SER136
A	MET291
A	HIS306
A	PHE307
A	HOH2561

---

site_id	AC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PG4 A 1350

Chain	Residue
A	TYR105
A	TYR176
A	GLY185
A	SER186
A	GLN187
A	ASN188
A	HOH2267
A	HOH2372
A	HOH2562

---

site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 1351

Chain	Residue
A	GLY205

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 1352

Chain	Residue
A	MET291
A	HOH2254

---

site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 1353

Chain	Residue
A	ASN294

---

site_id	BC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 1354

Chain	Residue
A	GLY65

---

site_id	BC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 1355

Chain	Residue
A	ASP84

---

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 1356

Chain	Residue
A	TYR204

---

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 1357

Chain	Residue
A	THR5
A	LYS12
A	GLY20
A	SER35
A	IOD1343
A	HOH2015

---

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA A 1358

Chain	Residue
A	TYR173
A	TYR204
A	SER250
A	PHE251
A	HOH2498

---

site_id	BC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 1359

Chain	Residue
A	HOH2535

---

site_id	BC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 1360

Chain	Residue
A	THR41
A	HOH2536

---