Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003924 | molecular_function | GTPase activity |
A | 0005525 | molecular_function | GTP binding |
A | 0006913 | biological_process | nucleocytoplasmic transport |
B | 0005515 | molecular_function | protein binding |
B | 0005634 | cellular_component | nucleus |
B | 0005737 | cellular_component | cytoplasm |
B | 0006606 | biological_process | protein import into nucleus |
B | 0006886 | biological_process | intracellular protein transport |
B | 0015031 | biological_process | protein transport |
B | 0031267 | molecular_function | small GTPase binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 25 |
Details | BINDING SITE FOR RESIDUE GTP A 1181 |
Chain | Residue |
A | GLY21 |
A | LYS40 |
A | TYR41 |
A | ALA43 |
A | THR44 |
A | GLY70 |
A | LEU71 |
A | ASN124 |
A | LYS125 |
A | ASP127 |
A | VAL128 |
A | GLY22 |
A | SER152 |
A | ALA153 |
A | LYS154 |
A | MG1182 |
A | HOH2015 |
A | HOH2016 |
A | GLY24 |
A | LYS25 |
A | THR26 |
A | THR27 |
A | PHE37 |
A | GLU38 |
A | LYS39 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MG A 1182 |
Chain | Residue |
A | THR26 |
A | THR44 |
A | GTP1181 |
A | HOH2016 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 164 |
Details | Domain: {"description":"Small GTPase Ran-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00752","evidenceCode":"ECO:0000255"}]} |
site_id | SWS_FT_FI2 |
Number of Residues | 8 |
Details | Region: {"description":"Switch-I","evidences":[{"source":"PROSITE-ProRule","id":"PRU00752","evidenceCode":"ECO:0000255"}]} |
site_id | SWS_FT_FI3 |
Number of Residues | 16 |
Details | Region: {"description":"Switch-II","evidences":[{"source":"PROSITE-ProRule","id":"PRU00752","evidenceCode":"ECO:0000255"}]} |
site_id | SWS_FT_FI4 |
Number of Residues | 13 |
Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P62825","evidenceCode":"ECO:0000250"}]} |
site_id | SWS_FT_FI5 |
Number of Residues | 32 |
Details | Repeat: {"description":"HEAT 2","evidences":[{"source":"PubMed","id":"20122403","evidenceCode":"ECO:0000269"}]} |
site_id | SWS_FT_FI6 |
Number of Residues | 40 |
Details | Repeat: {"description":"HEAT 3","evidences":[{"source":"PubMed","id":"20122403","evidenceCode":"ECO:0000269"}]} |
site_id | SWS_FT_FI7 |
Number of Residues | 37 |
Details | Repeat: {"description":"HEAT 5","evidences":[{"source":"PubMed","id":"20122403","evidenceCode":"ECO:0000269"}]} |
site_id | SWS_FT_FI8 |
Number of Residues | 32 |
Details | Repeat: {"description":"HEAT 6","evidences":[{"source":"PubMed","id":"20122403","evidenceCode":"ECO:0000269"}]} |
site_id | SWS_FT_FI9 |
Number of Residues | 36 |
Details | Repeat: {"description":"HEAT 10","evidences":[{"source":"PubMed","id":"20122403","evidenceCode":"ECO:0000269"}]} |
site_id | SWS_FT_FI10 |
Number of Residues | 40 |
Details | Repeat: {"description":"HEAT 15","evidences":[{"source":"PubMed","id":"20122403","evidenceCode":"ECO:0000269"}]} |
site_id | SWS_FT_FI11 |
Number of Residues | 30 |
Details | Repeat: {"description":"HEAT 18","evidences":[{"source":"PubMed","id":"20122403","evidenceCode":"ECO:0000269"}]} |