Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2X17

The X-ray structure of Ferritin from Pyrococcus furiosus loaded with Ag(I)

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0004322	molecular_function	ferroxidase activity
0	0005737	cellular_component	cytoplasm
0	0005829	cellular_component	cytosol
0	0006826	biological_process	iron ion transport
0	0006879	biological_process	intracellular iron ion homeostasis
0	0008198	molecular_function	ferrous iron binding
0	0008199	molecular_function	ferric iron binding
0	0016491	molecular_function	oxidoreductase activity
0	0042802	molecular_function	identical protein binding
0	0046872	molecular_function	metal ion binding
1	0004322	molecular_function	ferroxidase activity
1	0005737	cellular_component	cytoplasm
1	0005829	cellular_component	cytosol
1	0006826	biological_process	iron ion transport
1	0006879	biological_process	intracellular iron ion homeostasis
1	0008198	molecular_function	ferrous iron binding
1	0008199	molecular_function	ferric iron binding
1	0016491	molecular_function	oxidoreductase activity
1	0042802	molecular_function	identical protein binding
1	0046872	molecular_function	metal ion binding
2	0004322	molecular_function	ferroxidase activity
2	0005737	cellular_component	cytoplasm
2	0005829	cellular_component	cytosol
2	0006826	biological_process	iron ion transport
2	0006879	biological_process	intracellular iron ion homeostasis
2	0008198	molecular_function	ferrous iron binding
2	0008199	molecular_function	ferric iron binding
2	0016491	molecular_function	oxidoreductase activity
2	0042802	molecular_function	identical protein binding
2	0046872	molecular_function	metal ion binding
3	0004322	molecular_function	ferroxidase activity
3	0005737	cellular_component	cytoplasm
3	0005829	cellular_component	cytosol
3	0006826	biological_process	iron ion transport
3	0006879	biological_process	intracellular iron ion homeostasis
3	0008198	molecular_function	ferrous iron binding
3	0008199	molecular_function	ferric iron binding
3	0016491	molecular_function	oxidoreductase activity
3	0042802	molecular_function	identical protein binding
3	0046872	molecular_function	metal ion binding
4	0004322	molecular_function	ferroxidase activity
4	0005737	cellular_component	cytoplasm
4	0005829	cellular_component	cytosol
4	0006826	biological_process	iron ion transport
4	0006879	biological_process	intracellular iron ion homeostasis
4	0008198	molecular_function	ferrous iron binding
4	0008199	molecular_function	ferric iron binding
4	0016491	molecular_function	oxidoreductase activity
4	0042802	molecular_function	identical protein binding
4	0046872	molecular_function	metal ion binding
5	0004322	molecular_function	ferroxidase activity
5	0005737	cellular_component	cytoplasm
5	0005829	cellular_component	cytosol
5	0006826	biological_process	iron ion transport
5	0006879	biological_process	intracellular iron ion homeostasis
5	0008198	molecular_function	ferrous iron binding
5	0008199	molecular_function	ferric iron binding
5	0016491	molecular_function	oxidoreductase activity
5	0042802	molecular_function	identical protein binding
5	0046872	molecular_function	metal ion binding
6	0004322	molecular_function	ferroxidase activity
6	0005737	cellular_component	cytoplasm
6	0005829	cellular_component	cytosol
6	0006826	biological_process	iron ion transport
6	0006879	biological_process	intracellular iron ion homeostasis
6	0008198	molecular_function	ferrous iron binding
6	0008199	molecular_function	ferric iron binding
6	0016491	molecular_function	oxidoreductase activity
6	0042802	molecular_function	identical protein binding
6	0046872	molecular_function	metal ion binding
7	0004322	molecular_function	ferroxidase activity
7	0005737	cellular_component	cytoplasm
7	0005829	cellular_component	cytosol
7	0006826	biological_process	iron ion transport
7	0006879	biological_process	intracellular iron ion homeostasis
7	0008198	molecular_function	ferrous iron binding
7	0008199	molecular_function	ferric iron binding
7	0016491	molecular_function	oxidoreductase activity
7	0042802	molecular_function	identical protein binding
7	0046872	molecular_function	metal ion binding
8	0004322	molecular_function	ferroxidase activity
8	0005737	cellular_component	cytoplasm
8	0005829	cellular_component	cytosol
8	0006826	biological_process	iron ion transport
8	0006879	biological_process	intracellular iron ion homeostasis
8	0008198	molecular_function	ferrous iron binding
8	0008199	molecular_function	ferric iron binding
8	0016491	molecular_function	oxidoreductase activity
8	0042802	molecular_function	identical protein binding
8	0046872	molecular_function	metal ion binding
9	0004322	molecular_function	ferroxidase activity
9	0005737	cellular_component	cytoplasm
9	0005829	cellular_component	cytosol
9	0006826	biological_process	iron ion transport
9	0006879	biological_process	intracellular iron ion homeostasis
9	0008198	molecular_function	ferrous iron binding
9	0008199	molecular_function	ferric iron binding
9	0016491	molecular_function	oxidoreductase activity
9	0042802	molecular_function	identical protein binding
9	0046872	molecular_function	metal ion binding
G	0004322	molecular_function	ferroxidase activity
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006826	biological_process	iron ion transport
G	0006879	biological_process	intracellular iron ion homeostasis
G	0008198	molecular_function	ferrous iron binding
G	0008199	molecular_function	ferric iron binding
G	0016491	molecular_function	oxidoreductase activity
G	0042802	molecular_function	identical protein binding
G	0046872	molecular_function	metal ion binding
H	0004322	molecular_function	ferroxidase activity
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006826	biological_process	iron ion transport
H	0006879	biological_process	intracellular iron ion homeostasis
H	0008198	molecular_function	ferrous iron binding
H	0008199	molecular_function	ferric iron binding
H	0016491	molecular_function	oxidoreductase activity
H	0042802	molecular_function	identical protein binding
H	0046872	molecular_function	metal ion binding
I	0004322	molecular_function	ferroxidase activity
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006826	biological_process	iron ion transport
I	0006879	biological_process	intracellular iron ion homeostasis
I	0008198	molecular_function	ferrous iron binding
I	0008199	molecular_function	ferric iron binding
I	0016491	molecular_function	oxidoreductase activity
I	0042802	molecular_function	identical protein binding
I	0046872	molecular_function	metal ion binding
J	0004322	molecular_function	ferroxidase activity
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006826	biological_process	iron ion transport
J	0006879	biological_process	intracellular iron ion homeostasis
J	0008198	molecular_function	ferrous iron binding
J	0008199	molecular_function	ferric iron binding
J	0016491	molecular_function	oxidoreductase activity
J	0042802	molecular_function	identical protein binding
J	0046872	molecular_function	metal ion binding
K	0004322	molecular_function	ferroxidase activity
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0006826	biological_process	iron ion transport
K	0006879	biological_process	intracellular iron ion homeostasis
K	0008198	molecular_function	ferrous iron binding
K	0008199	molecular_function	ferric iron binding
K	0016491	molecular_function	oxidoreductase activity
K	0042802	molecular_function	identical protein binding
K	0046872	molecular_function	metal ion binding
L	0004322	molecular_function	ferroxidase activity
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0006826	biological_process	iron ion transport
L	0006879	biological_process	intracellular iron ion homeostasis
L	0008198	molecular_function	ferrous iron binding
L	0008199	molecular_function	ferric iron binding
L	0016491	molecular_function	oxidoreductase activity
L	0042802	molecular_function	identical protein binding
L	0046872	molecular_function	metal ion binding
M	0004322	molecular_function	ferroxidase activity
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0006826	biological_process	iron ion transport
M	0006879	biological_process	intracellular iron ion homeostasis
M	0008198	molecular_function	ferrous iron binding
M	0008199	molecular_function	ferric iron binding
M	0016491	molecular_function	oxidoreductase activity
M	0042802	molecular_function	identical protein binding
M	0046872	molecular_function	metal ion binding
N	0004322	molecular_function	ferroxidase activity
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0006826	biological_process	iron ion transport
N	0006879	biological_process	intracellular iron ion homeostasis
N	0008198	molecular_function	ferrous iron binding
N	0008199	molecular_function	ferric iron binding
N	0016491	molecular_function	oxidoreductase activity
N	0042802	molecular_function	identical protein binding
N	0046872	molecular_function	metal ion binding
O	0004322	molecular_function	ferroxidase activity
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0006826	biological_process	iron ion transport
O	0006879	biological_process	intracellular iron ion homeostasis
O	0008198	molecular_function	ferrous iron binding
O	0008199	molecular_function	ferric iron binding
O	0016491	molecular_function	oxidoreductase activity
O	0042802	molecular_function	identical protein binding
O	0046872	molecular_function	metal ion binding
P	0004322	molecular_function	ferroxidase activity
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0006826	biological_process	iron ion transport
P	0006879	biological_process	intracellular iron ion homeostasis
P	0008198	molecular_function	ferrous iron binding
P	0008199	molecular_function	ferric iron binding
P	0016491	molecular_function	oxidoreductase activity
P	0042802	molecular_function	identical protein binding
P	0046872	molecular_function	metal ion binding
Q	0004322	molecular_function	ferroxidase activity
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0006826	biological_process	iron ion transport
Q	0006879	biological_process	intracellular iron ion homeostasis
Q	0008198	molecular_function	ferrous iron binding
Q	0008199	molecular_function	ferric iron binding
Q	0016491	molecular_function	oxidoreductase activity
Q	0042802	molecular_function	identical protein binding
Q	0046872	molecular_function	metal ion binding
R	0004322	molecular_function	ferroxidase activity
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0006826	biological_process	iron ion transport
R	0006879	biological_process	intracellular iron ion homeostasis
R	0008198	molecular_function	ferrous iron binding
R	0008199	molecular_function	ferric iron binding
R	0016491	molecular_function	oxidoreductase activity
R	0042802	molecular_function	identical protein binding
R	0046872	molecular_function	metal ion binding
Y	0004322	molecular_function	ferroxidase activity
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0006826	biological_process	iron ion transport
Y	0006879	biological_process	intracellular iron ion homeostasis
Y	0008198	molecular_function	ferrous iron binding
Y	0008199	molecular_function	ferric iron binding
Y	0016491	molecular_function	oxidoreductase activity
Y	0042802	molecular_function	identical protein binding
Y	0046872	molecular_function	metal ion binding
Z	0004322	molecular_function	ferroxidase activity
Z	0005737	cellular_component	cytoplasm
Z	0005829	cellular_component	cytosol
Z	0006826	biological_process	iron ion transport
Z	0006879	biological_process	intracellular iron ion homeostasis
Z	0008198	molecular_function	ferrous iron binding
Z	0008199	molecular_function	ferric iron binding
Z	0016491	molecular_function	oxidoreductase activity
Z	0042802	molecular_function	identical protein binding
Z	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG 3 1172

Chain	Residue
3	MET153
9	MET153
K	MET153
Q	MET153

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG 7 1173

Chain	Residue
7	GLU49
7	HIS53
7	HOH2001
P	MET170

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG 1 1173

Chain	Residue
1	HIS53
1	HOH2001
J	MET170
1	GLU49

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG 1 1174

Chain	Residue
1	MET153
7	MET153
I	MET153
O	MET153

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE AG J 1173

Chain	Residue
1	MET170
J	GLU49
J	HIS53

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE AG Y 1171

Chain	Residue
G	MET170
Y	GLU49
Y	HIS53
Y	GLU126
Y	HOH2001

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE AG 4 1173

Chain	Residue
4	GLU49
4	HIS53
M	MET170

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG 9 1172

Chain	Residue
9	GLU49
9	HIS53
9	GLU126
R	MET170

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE AG 5 1173

Chain	Residue
5	GLU49
5	HIS53
N	MET170

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG 3 1173

Chain	Residue
3	GLU49
3	HIS53
3	HOH2002
L	MET170

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG 2 1172

Chain	Residue
2	GLU49
2	HIS53
2	HOH2001
K	MET170

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG 8 1173

Chain	Residue
8	GLU49
8	HIS53
8	HOH2001
Q	MET170

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG Z 1173

Chain	Residue
H	MET170
Z	GLU49
Z	HIS53
Z	HOH2001

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG I 1173

Chain	Residue
0	MET170
I	GLU49
I	HIS53
I	HOH2002

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE AG O 1171

Chain	Residue
6	MET170
O	GLU49
O	HIS53
O	GLU126
O	HOH2001

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG G 1172

Chain	Residue
G	GLU49
G	HIS53
G	GLU126
Y	MET170

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG P 1171

Chain	Residue
7	MET170
P	GLU49
P	HIS53
P	HOH2002

site_id	BC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE AG H 1173

Chain	Residue
H	GLU49
H	HIS53
Z	MET170

site_id	CC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE AG Q 1173

Chain	Residue
8	MET170
Q	GLU49
Q	HIS53

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG K 1172

Chain	Residue
2	MET170
K	GLU49
K	HIS53
K	HOH2001

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG L 1173

Chain	Residue
3	MET170
L	GLU49
L	HIS53
L	HOH2001

site_id	CC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG G 1173

Chain	Residue
0	MET153
2	MET153
G	MET153
H	MET153

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG N 1171

Chain	Residue
5	MET170
N	GLU49
N	HIS53
N	HOH2002

site_id	CC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE AG R 1172

Chain	Residue
9	MET170
R	GLU49
R	HIS53

site_id	CC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG M 1171

Chain	Residue
4	MET170
M	GLU49
M	HIS53
M	GLU126

site_id	CC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE AG 0 1172

Chain	Residue
0	GLU49
0	HIS53
I	MET170

site_id	CC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG 6 1172

Chain	Residue
6	GLU49
6	HIS53
6	GLU126
O	MET170

site_id	DC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG 5 1174

Chain	Residue
5	MET153
J	MET153
L	MET153
Y	MET153

site_id	DC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG 4 1174

Chain	Residue
4	MET153
P	MET153
R	MET153
Z	MET153

site_id	DC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AG 6 1173

Chain	Residue
6	MET153
8	MET153
M	MET153
N	MET153

site_id	DC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE AG M 1172

Chain	Residue
M	HIS93
M	PHE96
N	GLU110

site_id	DC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE AG 3 1174

Chain	Residue
3	MET1
3	ASN65
Y	TYR91

site_id	DC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE AG 1 1175

Chain	Residue
7	MET1

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)