Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0004459 | molecular_function | L-lactate dehydrogenase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0006089 | biological_process | lactate metabolic process |
A | 0006090 | biological_process | pyruvate metabolic process |
A | 0006099 | biological_process | tricarboxylic acid cycle |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
A | 0019752 | biological_process | carboxylic acid metabolic process |
A | 0030060 | molecular_function | L-malate dehydrogenase (NAD+) activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 22 |
Details | BINDING SITE FOR RESIDUE ENA A 1000 |
Chain | Residue |
A | GLY30 |
A | GLY99 |
A | ILE119 |
A | VAL138 |
A | ASN140 |
A | MET142 |
A | MET163 |
A | LEU167 |
A | HIS195 |
A | THR246 |
A | PRO250 |
A | ARG31 |
A | SO42000 |
A | HOH2029 |
A | HOH2030 |
A | VAL32 |
A | ASP53 |
A | ILE54 |
A | LEU58 |
A | TYR85 |
A | THR97 |
A | ALA98 |
site_id | AC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 A 2000 |
Chain | Residue |
A | ASN140 |
A | LEU167 |
A | ARG171 |
A | HIS195 |
A | ALA236 |
A | THR246 |
A | ENA1000 |
Functional Information from PROSITE/UniProt
site_id | PS00064 |
Number of Residues | 7 |
Details | L_LDH L-lactate dehydrogenase active site. IGEHGDS |
Chain | Residue | Details |
A | ILE192-SER198 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | HIS195 | |
Chain | Residue | Details |
A | GLY28 | |
A | ASP53 | |
A | ASN116 | |
A | VAL138 | |
Chain | Residue | Details |
A | ARG102 | |
A | ARG109 | |
A | ASN140 | |
A | ARG171 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1emd |
Chain | Residue | Details |
A | HIS195 | |
A | ASP168 | |
site_id | CSA2 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1emd |
Chain | Residue | Details |
A | HIS195 | |
A | ARG171 | |
A | ASP168 | |