Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019295 | biological_process | coenzyme M biosynthetic process |
| A | 0050545 | molecular_function | sulfopyruvate decarboxylase activity |
| A | 0102443 | molecular_function | L-2-hydroxycarboxylate dehydrogenase (NAD+) activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019295 | biological_process | coenzyme M biosynthetic process |
| B | 0050545 | molecular_function | sulfopyruvate decarboxylase activity |
| B | 0102443 | molecular_function | L-2-hydroxycarboxylate dehydrogenase (NAD+) activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0019295 | biological_process | coenzyme M biosynthetic process |
| C | 0050545 | molecular_function | sulfopyruvate decarboxylase activity |
| C | 0102443 | molecular_function | L-2-hydroxycarboxylate dehydrogenase (NAD+) activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0019295 | biological_process | coenzyme M biosynthetic process |
| D | 0050545 | molecular_function | sulfopyruvate decarboxylase activity |
| D | 0102443 | molecular_function | L-2-hydroxycarboxylate dehydrogenase (NAD+) activity |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0019295 | biological_process | coenzyme M biosynthetic process |
| E | 0050545 | molecular_function | sulfopyruvate decarboxylase activity |
| E | 0102443 | molecular_function | L-2-hydroxycarboxylate dehydrogenase (NAD+) activity |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0019295 | biological_process | coenzyme M biosynthetic process |
| F | 0050545 | molecular_function | sulfopyruvate decarboxylase activity |
| F | 0102443 | molecular_function | L-2-hydroxycarboxylate dehydrogenase (NAD+) activity |
| G | 0003824 | molecular_function | catalytic activity |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0019295 | biological_process | coenzyme M biosynthetic process |
| G | 0050545 | molecular_function | sulfopyruvate decarboxylase activity |
| G | 0102443 | molecular_function | L-2-hydroxycarboxylate dehydrogenase (NAD+) activity |
| H | 0003824 | molecular_function | catalytic activity |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0016491 | molecular_function | oxidoreductase activity |
| H | 0019295 | biological_process | coenzyme M biosynthetic process |
| H | 0050545 | molecular_function | sulfopyruvate decarboxylase activity |
| H | 0102443 | molecular_function | L-2-hydroxycarboxylate dehydrogenase (NAD+) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE NAD A 4001 |
| Chain | Residue |
| A | PHE41 |
| A | PRO158 |
| A | SER171 |
| A | ASP173 |
| A | MSE174 |
| A | ALA175 |
| A | LEU301 |
| A | PRO303 |
| A | GLY304 |
| A | ILE306 |
| A | GLU307 |
| A | HIS44 |
| A | HOH2065 |
| A | HOH2079 |
| B | PRO224 |
| B | LYS225 |
| B | TYR227 |
| A | HIS116 |
| A | PHE117 |
| A | GLY118 |
| A | ILE119 |
| A | ALA120 |
| A | THR140 |
| A | THR156 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE NAD B 4002 |
| Chain | Residue |
| A | PRO224 |
| A | LYS225 |
| B | PHE41 |
| B | HIS44 |
| B | HIS116 |
| B | GLY118 |
| B | ILE119 |
| B | ALA120 |
| B | THR140 |
| B | THR156 |
| B | PRO158 |
| B | SER171 |
| B | ASP173 |
| B | ALA175 |
| B | LEU301 |
| B | GLY304 |
| B | ILE306 |
| B | GLU307 |
| B | HOH2063 |
| site_id | AC3 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE NAD C 4003 |
| Chain | Residue |
| C | PHE41 |
| C | HIS44 |
| C | HIS116 |
| C | PHE117 |
| C | GLY118 |
| C | ILE119 |
| C | ALA120 |
| C | THR140 |
| C | THR156 |
| C | SER171 |
| C | ASP173 |
| C | ALA175 |
| C | LEU301 |
| C | GLY304 |
| C | ILE306 |
| C | GLU307 |
| C | HOH2053 |
| D | PHE147 |
| D | LYS225 |
| D | TYR227 |
| site_id | AC4 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE NAD D 4004 |
| Chain | Residue |
| C | PHE147 |
| C | PRO224 |
| C | LYS225 |
| C | TYR227 |
| D | PHE41 |
| D | HIS44 |
| D | HIS116 |
| D | PHE117 |
| D | GLY118 |
| D | ALA120 |
| D | THR140 |
| D | THR156 |
| D | SER171 |
| D | ASP173 |
| D | ALA175 |
| D | LEU301 |
| D | GLY304 |
| D | ILE306 |
| D | GLU307 |
| D | HOH2054 |
| D | HOH2055 |
| site_id | AC5 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE NAD E 4005 |
| Chain | Residue |
| E | HOH2064 |
| E | HOH2065 |
| F | PRO224 |
| F | LYS225 |
| F | TYR227 |
| E | PHE41 |
| E | HIS44 |
| E | HIS116 |
| E | PHE117 |
| E | GLY118 |
| E | ALA120 |
| E | THR140 |
| E | THR156 |
| E | SER171 |
| E | ASP173 |
| E | ALA175 |
| E | LEU301 |
| E | GLY304 |
| E | ILE306 |
| E | GLU307 |
| site_id | AC6 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE NAD F 4006 |
| Chain | Residue |
| E | PRO224 |
| E | LYS225 |
| E | TYR227 |
| F | PHE41 |
| F | HIS44 |
| F | HIS116 |
| F | PHE117 |
| F | GLY118 |
| F | ILE119 |
| F | ALA120 |
| F | THR140 |
| F | THR156 |
| F | ASP173 |
| F | ALA175 |
| F | LEU301 |
| F | PRO303 |
| F | GLY304 |
| F | ILE306 |
| F | GLU307 |
| site_id | AC7 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE NAD G 4007 |
| Chain | Residue |
| G | PHE41 |
| G | HIS44 |
| G | HIS116 |
| G | PHE117 |
| G | GLY118 |
| G | ALA120 |
| G | THR140 |
| G | THR156 |
| G | PRO158 |
| G | ASP173 |
| G | MSE174 |
| G | ALA175 |
| G | LEU301 |
| G | GLY304 |
| G | ILE306 |
| G | GLU307 |
| G | HOH2064 |
| G | HOH2069 |
| H | LYS225 |
| H | TYR227 |
| site_id | AC8 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE NAD H 4008 |
| Chain | Residue |
| G | PHE147 |
| G | PRO224 |
| G | LYS225 |
| G | TYR227 |
| G | HOH2040 |
| H | PHE41 |
| H | HIS44 |
| H | HIS116 |
| H | PHE117 |
| H | GLY118 |
| H | ILE119 |
| H | ALA120 |
| H | THR140 |
| H | THR156 |
| H | SER171 |
| H | ASP173 |
| H | ALA175 |
| H | LEU301 |
| H | GLY304 |
| H | ILE306 |
| H | GLU307 |
| H | HOH2052 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1s20 |
| Chain | Residue | Details |
| A | HIS44 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1s20 |
| Chain | Residue | Details |
| B | HIS44 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1s20 |
| Chain | Residue | Details |
| C | HIS44 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1s20 |
| Chain | Residue | Details |
| D | HIS44 |
| site_id | CSA5 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1s20 |
| Chain | Residue | Details |
| E | HIS44 |
| site_id | CSA6 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1s20 |
| Chain | Residue | Details |
| F | HIS44 |
| site_id | CSA7 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1s20 |
| Chain | Residue | Details |
| G | HIS44 |
| site_id | CSA8 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1s20 |
| Chain | Residue | Details |
| H | HIS44 |
