2X00

CRYSTAL STRUCTURE OF A-ACHBP IN COMPLEX WITH GYMNODIMINE A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE GYN A 301

Chain	Residue
A	TYR93
A	HOH2089
E	GLN38
E	TYR55
E	ILE118
A	LYS143
A	SER146
A	TRP147
A	TYR188
A	CYS190
A	TYR195
A	HOH2087
A	HOH2088

---

site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GYN B 301

Chain	Residue
A	TYR55
A	ILE118
A	SER167
B	TYR93
B	LYS143
B	SER146
B	TRP147
B	GLN186
B	TYR188
B	TYR195
B	HOH2071
B	HOH2072

---

site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GYN C 301

Chain	Residue
B	GLN38
B	TYR55
B	VAL108
B	ILE118
C	TYR93
C	LYS143
C	TRP147
C	VAL148
C	TYR188
C	CYS190
C	CYS191
C	TYR195

---

site_id	AC4
Number of Residues	15
Details	BINDING SITE FOR RESIDUE GYN D 301

Chain	Residue
C	GLN38
C	TYR55
C	VAL108
C	ILE118
C	HOH2016
D	TYR93
D	LYS143
D	SER146
D	TRP147
D	VAL148
D	TYR188
D	CYS190
D	TYR195
D	HOH2079
D	HOH2080

---

site_id	AC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GYN E 301

Chain	Residue
D	GLN38
D	TYR55
D	VAL108
D	ILE118
E	TYR93
E	LYS143
E	SER146
E	TRP147
E	TYR188
E	TYR195
E	HOH2079

---