2WZV
Crystal structure of the FMN-dependent nitroreductase NfnB from Mycobacterium smegmatis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0010181 | molecular_function | FMN binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0042178 | biological_process | xenobiotic catabolic process |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0050661 | molecular_function | NADP binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0010181 | molecular_function | FMN binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0042178 | biological_process | xenobiotic catabolic process |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE FMN A 801 |
| Chain | Residue |
| A | ARG25 |
| A | LEU182 |
| A | MSE203 |
| A | ILE221 |
| A | ARG223 |
| A | HOH2015 |
| A | HOH2109 |
| A | HOH2171 |
| A | HOH2172 |
| A | HOH2173 |
| A | HOH2174 |
| A | ARG26 |
| B | PRO52 |
| B | SER53 |
| B | ASN54 |
| B | ASN56 |
| B | ASP158 |
| B | ILE161 |
| B | PO41235 |
| A | ALA27 |
| A | ARG29 |
| A | PHE108 |
| A | TYR137 |
| A | PRO179 |
| A | GLN180 |
| A | ALA181 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE FMN B 801 |
| Chain | Residue |
| A | PRO52 |
| A | SER53 |
| A | ASN54 |
| A | ASP158 |
| A | ILE161 |
| A | PO41235 |
| B | ARG25 |
| B | ARG26 |
| B | ALA27 |
| B | ARG29 |
| B | PHE108 |
| B | TYR137 |
| B | PRO179 |
| B | GLN180 |
| B | ALA181 |
| B | LEU182 |
| B | ILE221 |
| B | ARG223 |
| B | HOH2094 |
| B | HOH2100 |
| B | HOH2173 |
| B | HOH2174 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1235 |
| Chain | Residue |
| A | SER55 |
| A | HOH2175 |
| A | HOH2176 |
| A | HOH2177 |
| A | HOH2178 |
| B | PHE108 |
| B | FMN801 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 B 1235 |
| Chain | Residue |
| A | PHE108 |
| A | FMN801 |
| B | SER55 |
| B | HOH2175 |
| B | HOH2176 |
| B | HOH2177 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 B 1236 |
| Chain | Residue |
| B | ARG32 |
| B | PRO33 |
| B | ASP34 |
| B | HIS173 |
| B | HOH2178 |
| B | HOH2179 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1236 |
| Chain | Residue |
| A | GLY24 |
| A | ARG26 |
| A | THR171 |
| A | ILE175 |
| A | HOH2013 |
| A | HOH2179 |
| A | HOH2180 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 1237 |
| Chain | Residue |
| A | ARG234 |
| B | ALA68 |
| B | ARG72 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 1237 |
| Chain | Residue |
| A | PRO91 |
| A | THR151 |
| A | GLU152 |
| B | ARG93 |
| B | GLU152 |
| B | ALA153 |
| B | HOH2074 |
| B | HOH2110 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20624223","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2WZV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WZW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20624223","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2WZW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20624223","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
