2WZT

Crystal structure of a mycobacterium aldo-keto reductase in its apo and liganded form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity
A	0044281	biological_process	small molecule metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0044281	biological_process	small molecule metabolic process

Functional Information from PROSITE/UniProt

site_id	PS00062
Number of Residues	18
Details	ALDOKETO_REDUCTASE_2 Aldo/keto reductase family signature 2. LmkvkedgiARSIGVCNF

Chain	Residue	Details
A	LEU132-PHE149

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site_id	PS00798
Number of Residues	18
Details	ALDOKETO_REDUCTASE_1 Aldo/keto reductase family signature 1. GYRLIDTAaaygnEaaVG

Chain	Residue	Details
A	GLY48-GLY65

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton donor => ECO:0000250|UniProtKB:P80874

Chain	Residue	Details
A	TYR58
B	TYR58

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site_id	SWS_FT_FI2
Number of Residues	22
Details	BINDING: BINDING => ECO:0000269|PubMed:20188740, ECO:0007744|PDB:2WZM

Chain	Residue	Details
A	ARG238
A	SER239
A	ALA240
A	ARG244
A	SER247
A	ASN248
A	ARG274
B	GLY196
B	LEU198
B	VAL200
B	ILE236
B	ARG238
B	SER239
B	ALA240
B	ARG244
B	SER247
B	ASN248
B	ARG274
A	GLY196
A	LEU198
A	VAL200
A	ILE236

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