2WYV
High resolution structure of Thermus thermophilus enoyl-acyl carrier protein reductase NAD-form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| C | 0006633 | biological_process | fatty acid biosynthetic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| D | 0006633 | biological_process | fatty acid biosynthetic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE NAD B 1260 |
| Chain | Residue |
| B | GLY15 |
| B | LEU145 |
| B | THR146 |
| B | LYS164 |
| B | ALA190 |
| B | HOH2134 |
| B | HOH2135 |
| B | THR17 |
| B | SER21 |
| B | LEU22 |
| B | GLN42 |
| B | VAL67 |
| B | ALA93 |
| B | ILE94 |
| B | ALA95 |
| site_id | AC2 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE NAD D 1258 |
| Chain | Residue |
| D | GLY15 |
| D | VAL16 |
| D | THR17 |
| D | SER21 |
| D | LEU22 |
| D | GLN42 |
| D | ALA65 |
| D | ASP66 |
| D | VAL67 |
| D | ALA93 |
| D | ILE94 |
| D | ALA95 |
| D | VAL120 |
| D | LEU145 |
| D | THR146 |
| D | LYS164 |
| D | ALA190 |
| D | GLY191 |
| D | PRO192 |
| D | VAL193 |
| D | THR195 |
| D | ALA197 |
| D | ALA198 |
| D | HOH2008 |
| D | HOH2057 |
| D | HOH2084 |
| D | HOH2129 |
| D | HOH2130 |
| D | HOH2131 |
| D | HOH2132 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA B 1261 |
| Chain | Residue |
| B | GLU100 |
| B | GLU103 |
| B | HOH2074 |
| B | HOH2075 |
| B | HOH2081 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 1258 |
| Chain | Residue |
| A | GLU100 |
| A | GLU103 |
| A | HOH2087 |
| A | HOH2088 |
| A | HOH2093 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA C 1260 |
| Chain | Residue |
| C | GLU100 |
| C | GLU103 |
| C | HOH2064 |
| C | HOH2066 |
| C | HOH2069 |
