2WYL
Apo structure of a metallo-b-lactamase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019854 | biological_process | L-ascorbic acid catabolic process |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0035460 | molecular_function | L-ascorbate 6-phosphate lactonase activity |
| A | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0019854 | biological_process | L-ascorbic acid catabolic process |
| B | 0030145 | molecular_function | manganese ion binding |
| B | 0035460 | molecular_function | L-ascorbate 6-phosphate lactonase activity |
| B | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0019854 | biological_process | L-ascorbic acid catabolic process |
| C | 0030145 | molecular_function | manganese ion binding |
| C | 0035460 | molecular_function | L-ascorbate 6-phosphate lactonase activity |
| C | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0019854 | biological_process | L-ascorbic acid catabolic process |
| D | 0030145 | molecular_function | manganese ion binding |
| D | 0035460 | molecular_function | L-ascorbate 6-phosphate lactonase activity |
| D | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0019854 | biological_process | L-ascorbic acid catabolic process |
| E | 0030145 | molecular_function | manganese ion binding |
| E | 0035460 | molecular_function | L-ascorbate 6-phosphate lactonase activity |
| E | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0019854 | biological_process | L-ascorbic acid catabolic process |
| F | 0030145 | molecular_function | manganese ion binding |
| F | 0035460 | molecular_function | L-ascorbate 6-phosphate lactonase activity |
| F | 0052689 | molecular_function | carboxylic ester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1339 |
| Chain | Residue |
| A | TRP23 |
| A | GLU27 |
| A | GLY318 |
| A | TYR332 |
| A | PRO335 |
| A | HOH2068 |
| F | LEU95 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 1340 |
| Chain | Residue |
| A | LEU114 |
| A | HIS122 |
| A | ILE123 |
| A | ASP124 |
| A | VAL127 |
| A | TRP151 |
| A | ASP61 |
| A | PHE62 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 1341 |
| Chain | Residue |
| A | ASP149 |
| C | ASN126 |
| D | ILE7 |
| D | SER11 |
| D | SER15 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 1338 |
| Chain | Residue |
| B | TRP23 |
| B | GLU27 |
| B | GLY318 |
| B | PRO335 |
| B | HOH2059 |
| E | PRO93 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL B 1339 |
| Chain | Residue |
| B | ASP61 |
| B | PHE62 |
| B | LEU114 |
| B | ALA115 |
| B | HIS122 |
| B | ILE123 |
| B | ASP124 |
| B | VAL127 |
| B | ALA128 |
| B | TRP151 |
| B | HOH2009 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FOR C 1337 |
| Chain | Residue |
| C | MSE1 |
| E | SER15 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 1338 |
| Chain | Residue |
| C | ASN25 |
| C | GLU29 |
| C | ILE107 |
| C | ARG108 |
| C | GLN109 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL C 1339 |
| Chain | Residue |
| C | TRP23 |
| C | GLU27 |
| C | GLY318 |
| C | TYR334 |
| C | PRO335 |
| C | HOH2071 |
| D | PRO93 |
| D | LEU95 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL C 1340 |
| Chain | Residue |
| C | ASP61 |
| C | PHE62 |
| C | LEU114 |
| C | ALA115 |
| C | HIS122 |
| C | ILE123 |
| C | ASP124 |
| C | TRP151 |
| C | HOH2011 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL C 1341 |
| Chain | Residue |
| C | LYS275 |
| C | GLY309 |
| C | LYS311 |
| C | LYS327 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL D 1340 |
| Chain | Residue |
| D | ASN25 |
| D | TRP49 |
| D | ALA106 |
| D | ILE107 |
| D | ARG108 |
| D | GLN109 |
| site_id | BC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL D 1341 |
| Chain | Residue |
| D | HOH2086 |
| site_id | BC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL D 1342 |
| Chain | Residue |
| C | LEU95 |
| D | TRP23 |
| D | LEU24 |
| D | GLU27 |
| D | GLY318 |
| D | TYR332 |
| D | PRO335 |
| D | HOH2084 |
| site_id | BC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL D 1343 |
| Chain | Residue |
| D | ASP61 |
| D | PHE62 |
| D | LEU114 |
| D | ALA115 |
| D | HIS122 |
| D | ILE123 |
| D | ASP124 |
| D | VAL127 |
| D | TRP151 |
| site_id | BC6 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL E 1339 |
| Chain | Residue |
| E | TRP151 |
| E | ASP61 |
| E | PHE62 |
| E | VAL113 |
| E | LEU114 |
| E | ALA115 |
| E | HIS122 |
| E | ILE123 |
| E | ASP124 |
| E | VAL127 |
| E | ALA128 |
| site_id | BC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL E 1340 |
| Chain | Residue |
| E | ASN25 |
| E | GLU29 |
| E | TRP49 |
| E | ASN57 |
| E | ILE107 |
| E | ARG108 |
| E | GLN109 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL E 1341 |
| Chain | Residue |
| E | GLY309 |
| E | PHE310 |
| E | LYS311 |
| E | LYS327 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL E 1342 |
| Chain | Residue |
| A | ARG305 |
| B | GLN316 |
| B | HOH2038 |
| E | GLN289 |
| E | ALA290 |
| E | ASP291 |
| site_id | CC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FOR F 1338 |
| Chain | Residue |
| C | SER15 |
| F | MSE1 |
| site_id | CC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL F 1339 |
| Chain | Residue |
| F | ASP61 |
| F | PHE62 |
| F | LEU114 |
| F | HIS122 |
| F | ASP124 |
| F | VAL127 |
| F | TRP151 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL F 1340 |
| Chain | Residue |
| F | LYS275 |
| F | GLY309 |
| F | LYS311 |
| F | LYS327 |
| F | ASP328 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL F 1341 |
| Chain | Residue |
| A | GLN293 |
| A | GLU331 |
| F | GLN289 |
| F | ALA290 |
| F | ASP291 |
