2WXZ

Crystal structure of rat angiotensinogen in C2 space group

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000165	biological_process	MAPK cascade
A	0001543	biological_process	ovarian follicle rupture
A	0001568	biological_process	blood vessel development
A	0001658	biological_process	branching involved in ureteric bud morphogenesis
A	0001819	biological_process	positive regulation of cytokine production
A	0001822	biological_process	kidney development
A	0001991	biological_process	regulation of systemic arterial blood pressure by circulatory renin-angiotensin
A	0001998	biological_process	angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure
A	0001999	biological_process	renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure
A	0002018	biological_process	renin-angiotensin regulation of aldosterone production
A	0002019	biological_process	regulation of renal output by angiotensin
A	0002027	biological_process	regulation of heart rate
A	0002034	biological_process	maintenance of blood vessel diameter homeostasis by renin-angiotensin
A	0002035	biological_process	brain renin-angiotensin system
A	0003014	biological_process	renal system process
A	0003051	biological_process	angiotensin-mediated drinking behavior
A	0003081	biological_process	regulation of systemic arterial blood pressure by renin-angiotensin
A	0003331	biological_process	positive regulation of extracellular matrix constituent secretion
A	0004867	molecular_function	serine-type endopeptidase inhibitor activity
A	0005179	molecular_function	hormone activity
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005739	cellular_component	mitochondrion
A	0006606	biological_process	protein import into nucleus
A	0006883	biological_process	intracellular sodium ion homeostasis
A	0007160	biological_process	cell-matrix adhesion
A	0007166	biological_process	cell surface receptor signaling pathway
A	0007186	biological_process	G protein-coupled receptor signaling pathway
A	0007204	biological_process	positive regulation of cytosolic calcium ion concentration
A	0007565	biological_process	female pregnancy
A	0008065	biological_process	establishment of blood-nerve barrier
A	0008217	biological_process	regulation of blood pressure
A	0008283	biological_process	cell population proliferation
A	0008284	biological_process	positive regulation of cell population proliferation
A	0008285	biological_process	negative regulation of cell population proliferation
A	0008306	biological_process	associative learning
A	0009409	biological_process	response to cold
A	0009612	biological_process	response to mechanical stimulus
A	0009651	biological_process	response to salt stress
A	0010468	biological_process	regulation of gene expression
A	0010595	biological_process	positive regulation of endothelial cell migration
A	0010613	biological_process	positive regulation of cardiac muscle hypertrophy
A	0010628	biological_process	positive regulation of gene expression
A	0010666	biological_process	positive regulation of cardiac muscle cell apoptotic process
A	0010718	biological_process	positive regulation of epithelial to mesenchymal transition
A	0010744	biological_process	positive regulation of macrophage derived foam cell differentiation
A	0010976	biological_process	positive regulation of neuron projection development
A	0014061	biological_process	regulation of norepinephrine secretion
A	0014824	biological_process	artery smooth muscle contraction
A	0014873	biological_process	response to muscle activity involved in regulation of muscle adaptation
A	0016525	biological_process	negative regulation of angiogenesis
A	0030103	biological_process	vasopressin secretion
A	0030198	biological_process	extracellular matrix organization
A	0030308	biological_process	negative regulation of cell growth
A	0030432	biological_process	peristalsis
A	0031702	molecular_function	type 1 angiotensin receptor binding
A	0031703	molecular_function	type 2 angiotensin receptor binding
A	0032355	biological_process	response to estradiol
A	0032930	biological_process	positive regulation of superoxide anion generation
A	0033138	biological_process	positive regulation of peptidyl-serine phosphorylation
A	0034104	biological_process	negative regulation of tissue remodeling
A	0035106	biological_process	operant conditioning
A	0035265	biological_process	organ growth
A	0035932	biological_process	aldosterone secretion
A	0038166	biological_process	angiotensin-activated signaling pathway
A	0040018	biological_process	positive regulation of multicellular organism growth
A	0042310	biological_process	vasoconstriction
A	0042311	biological_process	vasodilation
A	0042445	biological_process	hormone metabolic process
A	0042756	biological_process	drinking behavior
A	0042981	biological_process	regulation of apoptotic process
A	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
A	0043410	biological_process	positive regulation of MAPK cascade
A	0043524	biological_process	negative regulation of neuron apoptotic process
A	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
A	0045723	biological_process	positive regulation of fatty acid biosynthetic process
A	0045742	biological_process	positive regulation of epidermal growth factor receptor signaling pathway
A	0045777	biological_process	positive regulation of blood pressure
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0046622	biological_process	positive regulation of organ growth
A	0046628	biological_process	positive regulation of insulin receptor signaling pathway
A	0048143	biological_process	astrocyte activation
A	0048144	biological_process	fibroblast proliferation
A	0048146	biological_process	positive regulation of fibroblast proliferation
A	0048169	biological_process	regulation of long-term neuronal synaptic plasticity
A	0048659	biological_process	smooth muscle cell proliferation
A	0048662	biological_process	negative regulation of smooth muscle cell proliferation
A	0050727	biological_process	regulation of inflammatory response
A	0051145	biological_process	smooth muscle cell differentiation
A	0051247	biological_process	positive regulation of protein metabolic process
A	0051387	biological_process	negative regulation of neurotrophin TRK receptor signaling pathway
A	0051402	biological_process	neuron apoptotic process
A	0051403	biological_process	stress-activated MAPK cascade
A	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
A	0051924	biological_process	regulation of calcium ion transport
A	0051969	biological_process	regulation of transmission of nerve impulse
A	0061049	biological_process	cell growth involved in cardiac muscle cell development
A	0070371	biological_process	ERK1 and ERK2 cascade
A	0070471	biological_process	uterine smooth muscle contraction
A	0071260	biological_process	cellular response to mechanical stimulus
A	0090190	biological_process	positive regulation of branching involved in ureteric bud morphogenesis
A	1901201	biological_process	regulation of extracellular matrix assembly
A	1901203	biological_process	positive regulation of extracellular matrix assembly
A	1902895	biological_process	positive regulation of miRNA transcription
A	1903598	biological_process	positive regulation of gap junction assembly
A	1903779	biological_process	regulation of cardiac conduction
A	1904385	biological_process	cellular response to angiotensin
A	1904706	biological_process	negative regulation of vascular associated smooth muscle cell proliferation
A	1904707	biological_process	positive regulation of vascular associated smooth muscle cell proliferation
A	1904754	biological_process	positive regulation of vascular associated smooth muscle cell migration
A	1905010	biological_process	positive regulation of L-lysine import across plasma membrane
A	1905589	biological_process	positive regulation of L-arginine import across plasma membrane
A	1990776	biological_process	response to angiotensin
A	1990874	biological_process	vascular associated smooth muscle cell proliferation
A	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
C	0000165	biological_process	MAPK cascade
C	0001543	biological_process	ovarian follicle rupture
C	0001568	biological_process	blood vessel development
C	0001658	biological_process	branching involved in ureteric bud morphogenesis
C	0001819	biological_process	positive regulation of cytokine production
C	0001822	biological_process	kidney development
C	0001991	biological_process	regulation of systemic arterial blood pressure by circulatory renin-angiotensin
C	0001998	biological_process	angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure
C	0001999	biological_process	renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure
C	0002018	biological_process	renin-angiotensin regulation of aldosterone production
C	0002019	biological_process	regulation of renal output by angiotensin
C	0002027	biological_process	regulation of heart rate
C	0002034	biological_process	maintenance of blood vessel diameter homeostasis by renin-angiotensin
C	0002035	biological_process	brain renin-angiotensin system
C	0003014	biological_process	renal system process
C	0003051	biological_process	angiotensin-mediated drinking behavior
C	0003081	biological_process	regulation of systemic arterial blood pressure by renin-angiotensin
C	0003331	biological_process	positive regulation of extracellular matrix constituent secretion
C	0004867	molecular_function	serine-type endopeptidase inhibitor activity
C	0005179	molecular_function	hormone activity
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0005739	cellular_component	mitochondrion
C	0006606	biological_process	protein import into nucleus
C	0006883	biological_process	intracellular sodium ion homeostasis
C	0007160	biological_process	cell-matrix adhesion
C	0007166	biological_process	cell surface receptor signaling pathway
C	0007186	biological_process	G protein-coupled receptor signaling pathway
C	0007204	biological_process	positive regulation of cytosolic calcium ion concentration
C	0007565	biological_process	female pregnancy
C	0008065	biological_process	establishment of blood-nerve barrier
C	0008217	biological_process	regulation of blood pressure
C	0008283	biological_process	cell population proliferation
C	0008284	biological_process	positive regulation of cell population proliferation
C	0008285	biological_process	negative regulation of cell population proliferation
C	0008306	biological_process	associative learning
C	0009409	biological_process	response to cold
C	0009612	biological_process	response to mechanical stimulus
C	0009651	biological_process	response to salt stress
C	0010468	biological_process	regulation of gene expression
C	0010595	biological_process	positive regulation of endothelial cell migration
C	0010613	biological_process	positive regulation of cardiac muscle hypertrophy
C	0010628	biological_process	positive regulation of gene expression
C	0010666	biological_process	positive regulation of cardiac muscle cell apoptotic process
C	0010718	biological_process	positive regulation of epithelial to mesenchymal transition
C	0010744	biological_process	positive regulation of macrophage derived foam cell differentiation
C	0010976	biological_process	positive regulation of neuron projection development
C	0014061	biological_process	regulation of norepinephrine secretion
C	0014824	biological_process	artery smooth muscle contraction
C	0014873	biological_process	response to muscle activity involved in regulation of muscle adaptation
C	0016525	biological_process	negative regulation of angiogenesis
C	0030103	biological_process	vasopressin secretion
C	0030198	biological_process	extracellular matrix organization
C	0030308	biological_process	negative regulation of cell growth
C	0030432	biological_process	peristalsis
C	0031702	molecular_function	type 1 angiotensin receptor binding
C	0031703	molecular_function	type 2 angiotensin receptor binding
C	0032355	biological_process	response to estradiol
C	0032930	biological_process	positive regulation of superoxide anion generation
C	0033138	biological_process	positive regulation of peptidyl-serine phosphorylation
C	0034104	biological_process	negative regulation of tissue remodeling
C	0035106	biological_process	operant conditioning
C	0035265	biological_process	organ growth
C	0035932	biological_process	aldosterone secretion
C	0038166	biological_process	angiotensin-activated signaling pathway
C	0040018	biological_process	positive regulation of multicellular organism growth
C	0042310	biological_process	vasoconstriction
C	0042311	biological_process	vasodilation
C	0042445	biological_process	hormone metabolic process
C	0042756	biological_process	drinking behavior
C	0042981	biological_process	regulation of apoptotic process
C	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
C	0043410	biological_process	positive regulation of MAPK cascade
C	0043524	biological_process	negative regulation of neuron apoptotic process
C	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
C	0045723	biological_process	positive regulation of fatty acid biosynthetic process
C	0045742	biological_process	positive regulation of epidermal growth factor receptor signaling pathway
C	0045777	biological_process	positive regulation of blood pressure
C	0045893	biological_process	positive regulation of DNA-templated transcription
C	0046622	biological_process	positive regulation of organ growth
C	0046628	biological_process	positive regulation of insulin receptor signaling pathway
C	0048143	biological_process	astrocyte activation
C	0048144	biological_process	fibroblast proliferation
C	0048146	biological_process	positive regulation of fibroblast proliferation
C	0048169	biological_process	regulation of long-term neuronal synaptic plasticity
C	0048659	biological_process	smooth muscle cell proliferation
C	0048662	biological_process	negative regulation of smooth muscle cell proliferation
C	0050727	biological_process	regulation of inflammatory response
C	0051145	biological_process	smooth muscle cell differentiation
C	0051247	biological_process	positive regulation of protein metabolic process
C	0051387	biological_process	negative regulation of neurotrophin TRK receptor signaling pathway
C	0051402	biological_process	neuron apoptotic process
C	0051403	biological_process	stress-activated MAPK cascade
C	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
C	0051924	biological_process	regulation of calcium ion transport
C	0051969	biological_process	regulation of transmission of nerve impulse
C	0061049	biological_process	cell growth involved in cardiac muscle cell development
C	0070371	biological_process	ERK1 and ERK2 cascade
C	0070471	biological_process	uterine smooth muscle contraction
C	0071260	biological_process	cellular response to mechanical stimulus
C	0090190	biological_process	positive regulation of branching involved in ureteric bud morphogenesis
C	1901201	biological_process	regulation of extracellular matrix assembly
C	1901203	biological_process	positive regulation of extracellular matrix assembly
C	1902895	biological_process	positive regulation of miRNA transcription
C	1903598	biological_process	positive regulation of gap junction assembly
C	1903779	biological_process	regulation of cardiac conduction
C	1904385	biological_process	cellular response to angiotensin
C	1904706	biological_process	negative regulation of vascular associated smooth muscle cell proliferation
C	1904707	biological_process	positive regulation of vascular associated smooth muscle cell proliferation
C	1904754	biological_process	positive regulation of vascular associated smooth muscle cell migration
C	1905010	biological_process	positive regulation of L-lysine import across plasma membrane
C	1905589	biological_process	positive regulation of L-arginine import across plasma membrane
C	1990776	biological_process	response to angiotensin
C	1990874	biological_process	vascular associated smooth muscle cell proliferation
C	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
C	ASN271
C	ASN295

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