2WW2
Structure of the Family GH92 Inverting Mannosidase BT2199 from Bacteroides thetaiotaomicron VPI-5482
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000224 | molecular_function | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006516 | biological_process | glycoprotein catabolic process |
| A | 0030246 | molecular_function | carbohydrate binding |
| B | 0000224 | molecular_function | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006516 | biological_process | glycoprotein catabolic process |
| B | 0030246 | molecular_function | carbohydrate binding |
| C | 0000224 | molecular_function | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0006516 | biological_process | glycoprotein catabolic process |
| C | 0030246 | molecular_function | carbohydrate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE MPD A 759 |
| Chain | Residue |
| A | ASN33 |
| A | HOH2785 |
| A | TYR77 |
| A | GLY639 |
| A | SER640 |
| A | HOH2019 |
| A | HOH2151 |
| A | HOH2152 |
| A | HOH2782 |
| A | HOH2784 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 799 |
| Chain | Residue |
| A | HIS123 |
| A | GLU126 |
| A | HOH2146 |
| A | HOH2151 |
| A | HOH2152 |
| A | HOH2782 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 800 |
| Chain | Residue |
| A | SER40 |
| A | TYR643 |
| A | GLY645 |
| A | ASP648 |
| A | HOH2677 |
| A | HOH2680 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 801 |
| Chain | Residue |
| A | GLY299 |
| A | GLY300 |
| A | GLN304 |
| A | ARG629 |
| A | LEU679 |
| A | ASN700 |
| A | HOH2786 |
| A | HOH2787 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 802 |
| Chain | Residue |
| A | PRO34 |
| A | ASN48 |
| A | TYR50 |
| A | TYR313 |
| A | ARG314 |
| A | LEU317 |
| A | HOH2043 |
| A | HOH2421 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 803 |
| Chain | Residue |
| A | SER71 |
| A | GLY72 |
| A | TRP73 |
| A | PRO93 |
| A | TRP94 |
| A | ASN96 |
| A | HOH2105 |
| A | HOH2788 |
| B | GLU562 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 804 |
| Chain | Residue |
| A | HIS46 |
| A | PRO91 |
| A | ASP354 |
| A | GOL805 |
| A | HOH2037 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 805 |
| Chain | Residue |
| A | PRO91 |
| A | PHE318 |
| A | ASP349 |
| A | ASN350 |
| A | GLY351 |
| A | THR355 |
| A | TRP391 |
| A | GOL804 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 806 |
| Chain | Residue |
| A | ARG184 |
| A | SER210 |
| A | ARG253 |
| A | HOH2335 |
| A | HOH2789 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 807 |
| Chain | Residue |
| A | HIS396 |
| A | ARG397 |
| A | GLY398 |
| A | ILE440 |
| A | HOH2257 |
| A | HOH2259 |
| A | HOH2790 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 800 |
| Chain | Residue |
| B | HIS123 |
| B | GLU126 |
| B | HOH2104 |
| B | HOH2106 |
| B | HOH2112 |
| B | HOH2114 |
| site_id | BC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 801 |
| Chain | Residue |
| B | GLY299 |
| B | GLY300 |
| B | GLN304 |
| B | ARG629 |
| B | LEU679 |
| B | LYS681 |
| B | HOH2647 |
| B | HOH2649 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 802 |
| Chain | Residue |
| B | ARG184 |
| B | PHE209 |
| B | SER210 |
| B | ARG253 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 803 |
| Chain | Residue |
| B | HIS603 |
| B | CYS644 |
| B | HOH2650 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 804 |
| Chain | Residue |
| B | HOH2651 |
| B | VAL55 |
| B | PRO56 |
| B | SER149 |
| B | GLN287 |
| B | GLU321 |
| B | HOH2316 |
| site_id | BC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SWA B 900 |
| Chain | Residue |
| B | SER92 |
| B | TRP353 |
| B | ASP354 |
| B | TRP391 |
| B | CYS399 |
| B | MET400 |
| B | GLU537 |
| B | ASP648 |
| B | HOH2549 |
| B | HOH2550 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA C 800 |
| Chain | Residue |
| C | HIS123 |
| C | GLU126 |
| C | HOH2115 |
| C | HOH2119 |
| C | HOH2124 |
| C | HOH2125 |
| site_id | BC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL C 801 |
| Chain | Residue |
| C | GLY299 |
| C | GLY300 |
| C | GLN304 |
| C | ARG629 |
| C | LEU679 |
| C | LYS681 |
| C | HOH2618 |
| C | HOH2619 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 802 |
| Chain | Residue |
| C | SER92 |
| C | TRP94 |
| C | HOH2620 |
| C | HOH2621 |
| C | HOH2622 |
| site_id | CC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL C 803 |
| Chain | Residue |
| C | ASN649 |
| C | GLY650 |
| C | GLN651 |
| C | HOH2624 |
| C | HOH2625 |
| C | HOH2626 |
| C | HOH2627 |
