2WW0
Structure of the Family GH92 Inverting Mannosidase BT3990 from Bacteroides thetaiotaomicron VPI-5482
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000224 | molecular_function | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006516 | biological_process | glycoprotein catabolic process |
| A | 0030246 | molecular_function | carbohydrate binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000224 | molecular_function | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006516 | biological_process | glycoprotein catabolic process |
| B | 0030246 | molecular_function | carbohydrate binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000224 | molecular_function | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0006516 | biological_process | glycoprotein catabolic process |
| C | 0030246 | molecular_function | carbohydrate binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000224 | molecular_function | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0006516 | biological_process | glycoprotein catabolic process |
| D | 0030246 | molecular_function | carbohydrate binding |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0000224 | molecular_function | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
| E | 0005829 | cellular_component | cytosol |
| E | 0005975 | biological_process | carbohydrate metabolic process |
| E | 0006516 | biological_process | glycoprotein catabolic process |
| E | 0030246 | molecular_function | carbohydrate binding |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0000224 | molecular_function | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
| F | 0005829 | cellular_component | cytosol |
| F | 0005975 | biological_process | carbohydrate metabolic process |
| F | 0006516 | biological_process | glycoprotein catabolic process |
| F | 0030246 | molecular_function | carbohydrate binding |
| F | 0046872 | molecular_function | metal ion binding |
| G | 0000224 | molecular_function | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
| G | 0005829 | cellular_component | cytosol |
| G | 0005975 | biological_process | carbohydrate metabolic process |
| G | 0006516 | biological_process | glycoprotein catabolic process |
| G | 0030246 | molecular_function | carbohydrate binding |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0000224 | molecular_function | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
| H | 0005829 | cellular_component | cytosol |
| H | 0005975 | biological_process | carbohydrate metabolic process |
| H | 0006516 | biological_process | glycoprotein catabolic process |
| H | 0030246 | molecular_function | carbohydrate binding |
| H | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 800 |
| Chain | Residue |
| A | ASN601 |
| A | GLN602 |
| A | ASP644 |
| A | SWA801 |
| A | HOH2097 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SWA A 801 |
| Chain | Residue |
| A | MET394 |
| A | GLU533 |
| A | GLU585 |
| A | ASN601 |
| A | GLN602 |
| A | ASP644 |
| A | CA800 |
| A | SER86 |
| A | TRP347 |
| A | ASP348 |
| A | TRP385 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 802 |
| Chain | Residue |
| A | TYR126 |
| A | GLU272 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 803 |
| Chain | Residue |
| A | GLY293 |
| A | GLN298 |
| A | ARG625 |
| A | ASP629 |
| A | LEU675 |
| A | SER697 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 804 |
| Chain | Residue |
| A | PRO330 |
| A | TYR331 |
| A | HIS390 |
| A | HOH2117 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 805 |
| Chain | Residue |
| A | LYS315 |
| A | TYR317 |
| A | GLU367 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 806 |
| Chain | Residue |
| A | LYS619 |
| A | TYR702 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 800 |
| Chain | Residue |
| B | ASN601 |
| B | GLN602 |
| B | ASP644 |
| B | SWA801 |
| B | HOH2096 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SWA B 801 |
| Chain | Residue |
| B | TRP88 |
| B | TRP347 |
| B | ASP348 |
| B | TRP385 |
| B | MET394 |
| B | GLU533 |
| B | ASN601 |
| B | GLN602 |
| B | ASP644 |
| B | CA800 |
| B | HOH2096 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 802 |
| Chain | Residue |
| B | GLN284 |
| B | LYS288 |
| B | VAL364 |
| B | GLU684 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 803 |
| Chain | Residue |
| B | ALA275 |
| B | HOH2039 |
| B | HOH2041 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 804 |
| Chain | Residue |
| B | LYS315 |
| B | TYR317 |
| B | GLU367 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA C 800 |
| Chain | Residue |
| C | ASN601 |
| C | GLN602 |
| C | ASP644 |
| C | SWA801 |
| C | HOH2061 |
| site_id | BC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SWA C 801 |
| Chain | Residue |
| C | TRP88 |
| C | TRP347 |
| C | ASP348 |
| C | TRP385 |
| C | MET394 |
| C | GLU533 |
| C | ASN601 |
| C | GLN602 |
| C | ASP644 |
| C | CA800 |
| C | HOH2061 |
| site_id | BC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL C 802 |
| Chain | Residue |
| C | TYR702 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL C 803 |
| Chain | Residue |
| C | ASN195 |
| C | LYS197 |
| C | TYR199 |
| C | PHE253 |
| C | ILE254 |
| C | TYR328 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL C 804 |
| Chain | Residue |
| C | GLN284 |
| C | LYS288 |
| C | TYR361 |
| C | GLU684 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA D 800 |
| Chain | Residue |
| D | ASN601 |
| D | GLN602 |
| D | ASP644 |
| D | SWA801 |
| D | HOH2094 |
| site_id | CC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SWA D 801 |
| Chain | Residue |
| D | ASP644 |
| D | CA800 |
| D | HOH2094 |
| D | TRP88 |
| D | TRP347 |
| D | ASP348 |
| D | TRP385 |
| D | MET394 |
| D | GLU533 |
| D | ASN601 |
| D | GLN602 |
| site_id | CC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL D 802 |
| Chain | Residue |
| D | TYR126 |
| D | GLU272 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL D 803 |
| Chain | Residue |
| D | ASN709 |
| D | LYS725 |
| D | GLY727 |
| D | HOH2105 |
| site_id | CC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL D 804 |
| Chain | Residue |
| D | GLN284 |
| D | LYS288 |
| D | SER363 |
| D | GLU684 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA E 800 |
| Chain | Residue |
| E | ASN601 |
| E | GLN602 |
| E | ASP644 |
| E | SWA801 |
| site_id | CC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SWA E 801 |
| Chain | Residue |
| E | TRP347 |
| E | ASP348 |
| E | TRP385 |
| E | MET394 |
| E | GLU533 |
| E | ASN601 |
| E | GLN602 |
| E | ASP644 |
| E | CA800 |
| site_id | CC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL E 802 |
| Chain | Residue |
| B | GLY580 |
| E | ASN195 |
| E | TYR199 |
| E | ILE254 |
| E | VAL335 |
| site_id | CC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL E 803 |
| Chain | Residue |
| E | TYR126 |
| site_id | CC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA F 800 |
| Chain | Residue |
| F | ASN601 |
| F | GLN602 |
| F | ASP644 |
| F | SWA801 |
| site_id | DC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SWA F 801 |
| Chain | Residue |
| F | TRP347 |
| F | ASP348 |
| F | TRP385 |
| F | GLU533 |
| F | GLU585 |
| F | ASN601 |
| F | GLN602 |
| F | ASP644 |
| F | CA800 |
| site_id | DC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL F 802 |
| Chain | Residue |
| F | TYR126 |
| F | GLU272 |
| site_id | DC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA G 800 |
| Chain | Residue |
| G | ASN601 |
| G | GLN602 |
| G | ASP644 |
| G | SWA801 |
| site_id | DC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE SWA G 801 |
| Chain | Residue |
| G | TRP88 |
| G | TRP347 |
| G | ASP348 |
| G | TRP385 |
| G | MET394 |
| G | GLU533 |
| G | GLU585 |
| G | ASN601 |
| G | GLN602 |
| G | ASP642 |
| G | ASP644 |
| G | CA800 |
| site_id | DC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA H 800 |
| Chain | Residue |
| H | ASN601 |
| H | GLN602 |
| H | ASP644 |
| H | SWA801 |
| site_id | DC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SWA H 801 |
| Chain | Residue |
| H | TRP347 |
| H | ASP348 |
| H | TRP385 |
| H | GLU533 |
| H | GLU585 |
| H | ASN601 |
| H | GLN602 |
| H | ASP644 |
| H | CA800 |
