Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2WVW

Cryo-EM structure of the RbcL-RbcX complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004497	molecular_function	monooxygenase activity
A	0005515	molecular_function	protein binding
A	0009853	biological_process	photorespiration
A	0015977	biological_process	carbon fixation
A	0015979	biological_process	photosynthesis
A	0016829	molecular_function	lyase activity
A	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
A	0019253	biological_process	reductive pentose-phosphate cycle
A	0031470	cellular_component	carboxysome
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0004497	molecular_function	monooxygenase activity
B	0005515	molecular_function	protein binding
B	0009853	biological_process	photorespiration
B	0015977	biological_process	carbon fixation
B	0015979	biological_process	photosynthesis
B	0016829	molecular_function	lyase activity
B	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
B	0019253	biological_process	reductive pentose-phosphate cycle
B	0031470	cellular_component	carboxysome
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0004497	molecular_function	monooxygenase activity
C	0005515	molecular_function	protein binding
C	0009853	biological_process	photorespiration
C	0015977	biological_process	carbon fixation
C	0015979	biological_process	photosynthesis
C	0016829	molecular_function	lyase activity
C	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
C	0019253	biological_process	reductive pentose-phosphate cycle
C	0031470	cellular_component	carboxysome
C	0046872	molecular_function	metal ion binding
D	0000287	molecular_function	magnesium ion binding
D	0004497	molecular_function	monooxygenase activity
D	0005515	molecular_function	protein binding
D	0009853	biological_process	photorespiration
D	0015977	biological_process	carbon fixation
D	0015979	biological_process	photosynthesis
D	0016829	molecular_function	lyase activity
D	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
D	0019253	biological_process	reductive pentose-phosphate cycle
D	0031470	cellular_component	carboxysome
D	0046872	molecular_function	metal ion binding
E	0000287	molecular_function	magnesium ion binding
E	0004497	molecular_function	monooxygenase activity
E	0005515	molecular_function	protein binding
E	0009853	biological_process	photorespiration
E	0015977	biological_process	carbon fixation
E	0015979	biological_process	photosynthesis
E	0016829	molecular_function	lyase activity
E	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
E	0019253	biological_process	reductive pentose-phosphate cycle
E	0031470	cellular_component	carboxysome
E	0046872	molecular_function	metal ion binding
F	0000287	molecular_function	magnesium ion binding
F	0004497	molecular_function	monooxygenase activity
F	0005515	molecular_function	protein binding
F	0009853	biological_process	photorespiration
F	0015977	biological_process	carbon fixation
F	0015979	biological_process	photosynthesis
F	0016829	molecular_function	lyase activity
F	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
F	0019253	biological_process	reductive pentose-phosphate cycle
F	0031470	cellular_component	carboxysome
F	0046872	molecular_function	metal ion binding
G	0000287	molecular_function	magnesium ion binding
G	0004497	molecular_function	monooxygenase activity
G	0005515	molecular_function	protein binding
G	0009853	biological_process	photorespiration
G	0015977	biological_process	carbon fixation
G	0015979	biological_process	photosynthesis
G	0016829	molecular_function	lyase activity
G	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
G	0019253	biological_process	reductive pentose-phosphate cycle
G	0031470	cellular_component	carboxysome
G	0046872	molecular_function	metal ion binding
H	0000287	molecular_function	magnesium ion binding
H	0004497	molecular_function	monooxygenase activity
H	0005515	molecular_function	protein binding
H	0009853	biological_process	photorespiration
H	0015977	biological_process	carbon fixation
H	0015979	biological_process	photosynthesis
H	0016829	molecular_function	lyase activity
H	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
H	0019253	biological_process	reductive pentose-phosphate cycle
H	0031470	cellular_component	carboxysome
H	0046872	molecular_function	metal ion binding
I	0005515	molecular_function	protein binding
I	0005737	cellular_component	cytoplasm
I	0006457	biological_process	protein folding
I	0015977	biological_process	carbon fixation
I	0015979	biological_process	photosynthesis
I	0031470	cellular_component	carboxysome
I	0042803	molecular_function	protein homodimerization activity
I	0044183	molecular_function	protein folding chaperone
I	0110102	biological_process	ribulose bisphosphate carboxylase complex assembly
J	0005515	molecular_function	protein binding
J	0005737	cellular_component	cytoplasm
J	0006457	biological_process	protein folding
J	0015977	biological_process	carbon fixation
J	0015979	biological_process	photosynthesis
J	0031470	cellular_component	carboxysome
J	0042803	molecular_function	protein homodimerization activity
J	0044183	molecular_function	protein folding chaperone
J	0110102	biological_process	ribulose bisphosphate carboxylase complex assembly
K	0005515	molecular_function	protein binding
K	0005737	cellular_component	cytoplasm
K	0006457	biological_process	protein folding
K	0015977	biological_process	carbon fixation
K	0015979	biological_process	photosynthesis
K	0031470	cellular_component	carboxysome
K	0042803	molecular_function	protein homodimerization activity
K	0044183	molecular_function	protein folding chaperone
K	0110102	biological_process	ribulose bisphosphate carboxylase complex assembly
L	0005515	molecular_function	protein binding
L	0005737	cellular_component	cytoplasm
L	0006457	biological_process	protein folding
L	0015977	biological_process	carbon fixation
L	0015979	biological_process	photosynthesis
L	0031470	cellular_component	carboxysome
L	0042803	molecular_function	protein homodimerization activity
L	0044183	molecular_function	protein folding chaperone
L	0110102	biological_process	ribulose bisphosphate carboxylase complex assembly
M	0005515	molecular_function	protein binding
M	0005737	cellular_component	cytoplasm
M	0006457	biological_process	protein folding
M	0015977	biological_process	carbon fixation
M	0015979	biological_process	photosynthesis
M	0031470	cellular_component	carboxysome
M	0042803	molecular_function	protein homodimerization activity
M	0044183	molecular_function	protein folding chaperone
M	0110102	biological_process	ribulose bisphosphate carboxylase complex assembly
N	0005515	molecular_function	protein binding
N	0005737	cellular_component	cytoplasm
N	0006457	biological_process	protein folding
N	0015977	biological_process	carbon fixation
N	0015979	biological_process	photosynthesis
N	0031470	cellular_component	carboxysome
N	0042803	molecular_function	protein homodimerization activity
N	0044183	molecular_function	protein folding chaperone
N	0110102	biological_process	ribulose bisphosphate carboxylase complex assembly
O	0005515	molecular_function	protein binding
O	0005737	cellular_component	cytoplasm
O	0006457	biological_process	protein folding
O	0015977	biological_process	carbon fixation
O	0015979	biological_process	photosynthesis
O	0031470	cellular_component	carboxysome
O	0042803	molecular_function	protein homodimerization activity
O	0044183	molecular_function	protein folding chaperone
O	0110102	biological_process	ribulose bisphosphate carboxylase complex assembly
P	0005515	molecular_function	protein binding
P	0005737	cellular_component	cytoplasm
P	0006457	biological_process	protein folding
P	0015977	biological_process	carbon fixation
P	0015979	biological_process	photosynthesis
P	0031470	cellular_component	carboxysome
P	0042803	molecular_function	protein homodimerization activity
P	0044183	molecular_function	protein folding chaperone
P	0110102	biological_process	ribulose bisphosphate carboxylase complex assembly
Q	0005515	molecular_function	protein binding
Q	0005737	cellular_component	cytoplasm
Q	0006457	biological_process	protein folding
Q	0015977	biological_process	carbon fixation
Q	0015979	biological_process	photosynthesis
Q	0031470	cellular_component	carboxysome
Q	0042803	molecular_function	protein homodimerization activity
Q	0044183	molecular_function	protein folding chaperone
Q	0110102	biological_process	ribulose bisphosphate carboxylase complex assembly
R	0005515	molecular_function	protein binding
R	0005737	cellular_component	cytoplasm
R	0006457	biological_process	protein folding
R	0015977	biological_process	carbon fixation
R	0015979	biological_process	photosynthesis
R	0031470	cellular_component	carboxysome
R	0042803	molecular_function	protein homodimerization activity
R	0044183	molecular_function	protein folding chaperone
R	0110102	biological_process	ribulose bisphosphate carboxylase complex assembly
S	0005515	molecular_function	protein binding
S	0005737	cellular_component	cytoplasm
S	0006457	biological_process	protein folding
S	0015977	biological_process	carbon fixation
S	0015979	biological_process	photosynthesis
S	0031470	cellular_component	carboxysome
S	0042803	molecular_function	protein homodimerization activity
S	0044183	molecular_function	protein folding chaperone
S	0110102	biological_process	ribulose bisphosphate carboxylase complex assembly
T	0005515	molecular_function	protein binding
T	0005737	cellular_component	cytoplasm
T	0006457	biological_process	protein folding
T	0015977	biological_process	carbon fixation
T	0015979	biological_process	photosynthesis
T	0031470	cellular_component	carboxysome
T	0042803	molecular_function	protein homodimerization activity
T	0044183	molecular_function	protein folding chaperone
T	0110102	biological_process	ribulose bisphosphate carboxylase complex assembly
U	0005515	molecular_function	protein binding
U	0005737	cellular_component	cytoplasm
U	0006457	biological_process	protein folding
U	0015977	biological_process	carbon fixation
U	0015979	biological_process	photosynthesis
U	0031470	cellular_component	carboxysome
U	0042803	molecular_function	protein homodimerization activity
U	0044183	molecular_function	protein folding chaperone
U	0110102	biological_process	ribulose bisphosphate carboxylase complex assembly
V	0005515	molecular_function	protein binding
V	0005737	cellular_component	cytoplasm
V	0006457	biological_process	protein folding
V	0015977	biological_process	carbon fixation
V	0015979	biological_process	photosynthesis
V	0031470	cellular_component	carboxysome
V	0042803	molecular_function	protein homodimerization activity
V	0044183	molecular_function	protein folding chaperone
V	0110102	biological_process	ribulose bisphosphate carboxylase complex assembly
W	0005515	molecular_function	protein binding
W	0005737	cellular_component	cytoplasm
W	0006457	biological_process	protein folding
W	0015977	biological_process	carbon fixation
W	0015979	biological_process	photosynthesis
W	0031470	cellular_component	carboxysome
W	0042803	molecular_function	protein homodimerization activity
W	0044183	molecular_function	protein folding chaperone
W	0110102	biological_process	ribulose bisphosphate carboxylase complex assembly
X	0005515	molecular_function	protein binding
X	0005737	cellular_component	cytoplasm
X	0006457	biological_process	protein folding
X	0015977	biological_process	carbon fixation
X	0015979	biological_process	photosynthesis
X	0031470	cellular_component	carboxysome
X	0042803	molecular_function	protein homodimerization activity
X	0044183	molecular_function	protein folding chaperone
X	0110102	biological_process	ribulose bisphosphate carboxylase complex assembly

Functional Information from PROSITE/UniProt

site_id	PS00157
Number of Residues	9
Details	RUBISCO_LARGE Ribulose bisphosphate carboxylase large chain active site. GlDFtKdDE

Chain	Residue	Details
A	GLY196-GLU204

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	ACT_SITE: Proton acceptor

Chain	Residue	Details
A	LYS175
E	HIS294
F	LYS175
F	HIS294
G	LYS175
G	HIS294
H	LYS175
H	HIS294
A	HIS294
B	LYS175
B	HIS294
C	LYS175
C	HIS294
D	LYS175
D	HIS294
E	LYS175

site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: in homodimeric partner

Chain	Residue	Details
A	ASN123
B	ASN123
C	ASN123
D	ASN123
E	ASN123
F	ASN123
G	ASN123
H	ASN123

site_id	SWS_FT_FI3
Number of Residues	40
Details	BINDING:

Chain	Residue	Details
A	THR173
B	SER379
C	THR173
C	LYS177
C	ARG295
C	HIS327
C	SER379
D	THR173
D	LYS177
D	ARG295
D	HIS327
A	LYS177
D	SER379
E	THR173
E	LYS177
E	ARG295
E	HIS327
E	SER379
F	THR173
F	LYS177
F	ARG295
F	HIS327
A	ARG295
F	SER379
G	THR173
G	LYS177
G	ARG295
G	HIS327
G	SER379
H	THR173
H	LYS177
H	ARG295
H	HIS327
A	HIS327
H	SER379
A	SER379
B	THR173
B	LYS177
B	ARG295
B	HIS327

site_id	SWS_FT_FI4
Number of Residues	8
Details	BINDING: via carbamate group => ECO:0000269\|PubMed:8245022

Chain	Residue	Details
A	LYS201
B	LYS201
C	LYS201
D	LYS201
E	LYS201
F	LYS201
G	LYS201
H	LYS201

site_id	SWS_FT_FI5
Number of Residues	16
Details	BINDING: BINDING => ECO:0000269\|PubMed:8245022

Chain	Residue	Details
A	ASP203
E	GLU204
F	ASP203
F	GLU204
G	ASP203
G	GLU204
H	ASP203
H	GLU204
A	GLU204
B	ASP203
B	GLU204
C	ASP203
C	GLU204
D	ASP203
D	GLU204
E	ASP203

site_id	SWS_FT_FI6
Number of Residues	8
Details	SITE: Transition state stabilizer

Chain	Residue	Details
A	LYS334
B	LYS334
C	LYS334
D	LYS334
E	LYS334
F	LYS334
G	LYS334
H	LYS334

site_id	SWS_FT_FI7
Number of Residues	8
Details	MOD_RES: N6-carboxylysine => ECO:0000269\|PubMed:16593333

Chain	Residue	Details
A	LYS201
B	LYS201
C	LYS201
D	LYS201
E	LYS201
F	LYS201
G	LYS201
H	LYS201

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	6
Details	M-CSA 907

Chain	Residue	Details
A	LYS175	electrostatic stabiliser, metal ligand, proton donor
A	LYS201	metal ligand, nucleophile, proton donor
A	ASP203	metal ligand
A	GLU204	metal ligand
A	HIS294	proton acceptor
A	LYS334	electrostatic stabiliser

site_id	MCSA2
Number of Residues	6
Details	M-CSA 907

Chain	Residue	Details
B	LYS175	electrostatic stabiliser, metal ligand, proton donor
B	LYS201	metal ligand, nucleophile, proton donor
B	ASP203	metal ligand
B	GLU204	metal ligand
B	HIS294	proton acceptor
B	LYS334	electrostatic stabiliser

site_id	MCSA3
Number of Residues	6
Details	M-CSA 907

Chain	Residue	Details
C	LYS175	electrostatic stabiliser, metal ligand, proton donor
C	LYS201	metal ligand, nucleophile, proton donor
C	ASP203	metal ligand
C	GLU204	metal ligand
C	HIS294	proton acceptor
C	LYS334	electrostatic stabiliser

site_id	MCSA4
Number of Residues	6
Details	M-CSA 907

Chain	Residue	Details
D	LYS175	electrostatic stabiliser, metal ligand, proton donor
D	LYS201	metal ligand, nucleophile, proton donor
D	ASP203	metal ligand
D	GLU204	metal ligand
D	HIS294	proton acceptor
D	LYS334	electrostatic stabiliser

site_id	MCSA5
Number of Residues	6
Details	M-CSA 907

Chain	Residue	Details
E	LYS175	electrostatic stabiliser, metal ligand, proton donor
E	LYS201	metal ligand, nucleophile, proton donor
E	ASP203	metal ligand
E	GLU204	metal ligand
E	HIS294	proton acceptor
E	LYS334	electrostatic stabiliser

site_id	MCSA6
Number of Residues	6
Details	M-CSA 907

Chain	Residue	Details
F	LYS175	electrostatic stabiliser, metal ligand, proton donor
F	LYS201	metal ligand, nucleophile, proton donor
F	ASP203	metal ligand
F	GLU204	metal ligand
F	HIS294	proton acceptor
F	LYS334	electrostatic stabiliser

site_id	MCSA7
Number of Residues	6
Details	M-CSA 907

Chain	Residue	Details
G	LYS175	electrostatic stabiliser, metal ligand, proton donor
G	LYS201	metal ligand, nucleophile, proton donor
G	ASP203	metal ligand
G	GLU204	metal ligand
G	HIS294	proton acceptor
G	LYS334	electrostatic stabiliser

site_id	MCSA8
Number of Residues	6
Details	M-CSA 907

Chain	Residue	Details
H	LYS175	electrostatic stabiliser, metal ligand, proton donor
H	LYS201	metal ligand, nucleophile, proton donor
H	ASP203	metal ligand
H	GLU204	metal ligand
H	HIS294	proton acceptor
H	LYS334	electrostatic stabiliser

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)