Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008236 | molecular_function | serine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 1276 |
| Chain | Residue |
| A | GLN2 |
| A | SER184 |
| A | ASN185 |
| A | LEU257 |
| A | TYR263 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 1277 |
| Chain | Residue |
| A | ASN97 |
| A | ALA254 |
| A | LYS265 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 1278 |
| Chain | Residue |
| A | SER242 |
| A | GLN245 |
| A | ASN240 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 1301 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 1279 |
| Chain | Residue |
| A | ASN158 |
| A | CS1292 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 1280 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 1281 |
| Chain | Residue |
| A | SER99 |
| A | ASN248 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 1282 |
| Chain | Residue |
| A | PRO40 |
| A | LEU42 |
| A | LEU75 |
| A | CS1283 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CS A 1283 |
| Chain | Residue |
| A | ALA37 |
| A | HIS39 |
| A | LEU42 |
| A | CL1282 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CS A 1284 |
| Chain | Residue |
| A | GLY193 |
| A | ALA194 |
| A | LEU196 |
| A | SER260 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CS A 1285 |
| Chain | Residue |
| A | GLY61 |
| A | SER98 |
| A | HOH2041 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CS A 1286 |
| Chain | Residue |
| A | GLN2 |
| A | ASN77 |
| A | ASN185 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CS A 1287 |
| Chain | Residue |
| A | ALA52 |
| A | TYR256 |
| A | CCN1299 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CS A 1288 |
| Chain | Residue |
| A | TYR143 |
| A | SER244 |
| A | HOH2101 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CS A 1289 |
| Chain | Residue |
| A | PRO239 |
| A | LEU241 |
| A | HOH2052 |
| site_id | BC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CS A 1290 |
| Chain | Residue |
| A | ALA254 |
| A | HOH2040 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CS A 1291 |
| Chain | Residue |
| A | ALA1 |
| A | THR3 |
| A | GLY80 |
| A | HOH2086 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CS A 1292 |
| Chain | Residue |
| A | SER156 |
| A | ASN158 |
| A | CL1279 |
| site_id | CC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CS A 1293 |
| Chain | Residue |
| A | SER182 |
| A | ASN183 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 1294 |
| Chain | Residue |
| A | GLN2 |
| A | ASP41 |
| A | LEU75 |
| A | ASN77 |
| A | THR79 |
| A | VAL81 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 1295 |
| Chain | Residue |
| A | ALA169 |
| A | TYR171 |
| A | VAL174 |
| A | HOH2070 |
| A | HOH2083 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CCN A 1296 |
| Chain | Residue |
| A | GLY127 |
| A | GLY154 |
| A | SER221 |
| A | CCN1297 |
| A | HOH2065 |
| site_id | CC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CCN A 1297 |
| Chain | Residue |
| A | ASN155 |
| A | GLY219 |
| A | THR220 |
| A | SER221 |
| A | CCN1296 |
| A | HOH2095 |
| site_id | CC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CCN A 1298 |
| Chain | Residue |
| A | ASN62 |
| A | ASN117 |
| A | HOH2110 |
| site_id | CC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CCN A 1299 |
| Chain | Residue |
| A | VAL51 |
| A | ALA52 |
| A | TYR256 |
| A | CS1287 |
| A | HOH2040 |
| A | HOH2111 |
| A | HOH2112 |
| site_id | CC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CCN A 1300 |
| Chain | Residue |
| A | SER101 |
| A | GLY102 |
| A | GLY127 |
| A | HOH2055 |
| A | HOH2113 |
Functional Information from PROSITE/UniProt
| site_id | PS00136 |
| Number of Residues | 12 |
| Details | SUBTILASE_ASP Serine proteases, subtilase family, aspartic acid active site. VAVLDTGIqasH |
| Chain | Residue | Details |
| A | VAL28-HIS39 | |
| site_id | PS00137 |
| Number of Residues | 11 |
| Details | SUBTILASE_HIS Serine proteases, subtilase family, histidine active site. HGThVAGtVAA |
| Chain | Residue | Details |
| A | HIS64-ALA74 | |
| site_id | PS00138 |
| Number of Residues | 11 |
| Details | SUBTILASE_SER Serine proteases, subtilase family, serine active site. GTSmAsPhVAG |
| Chain | Residue | Details |
| A | GLY219-GLY229 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 268 |
| Details | Domain: {"description":"Peptidase S8","evidences":[{"source":"PROSITE-ProRule","id":"PRU01240","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PROSITE-ProRule","id":"PRU01240","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"8512925","evidenceCode":"ECO:0000269"}]} |
