Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000922 | cellular_component | spindle pole |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005813 | cellular_component | centrosome |
| A | 0005815 | cellular_component | microtubule organizing center |
| A | 0005856 | cellular_component | cytoskeleton |
| A | 0005874 | cellular_component | microtubule |
| A | 0006338 | biological_process | chromatin remodeling |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0007346 | biological_process | regulation of mitotic cell cycle |
| A | 0016310 | biological_process | phosphorylation |
| A | 0032206 | biological_process | positive regulation of telomere maintenance |
| A | 0035865 | biological_process | cellular response to potassium ion |
| A | 0044024 | molecular_function | histone H2AS1 kinase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051225 | biological_process | spindle assembly |
| A | 0106310 | molecular_function | protein serine kinase activity |
| A | 0140677 | molecular_function | molecular function activator activity |
| A | 1900227 | biological_process | positive regulation of NLRP3 inflammasome complex assembly |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE ADP A 1301 |
| Chain | Residue |
| A | GLY43 |
| A | ASP179 |
| A | MG1303 |
| A | GLN44 |
| A | PHE45 |
| A | SER46 |
| A | VAL48 |
| A | ALA61 |
| A | LYS63 |
| A | GLU112 |
| A | ALA114 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NI A 1302 |
| Chain | Residue |
| A | HIS209 |
| A | HIS209 |
| A | CYS247 |
| A | CYS247 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG A 1303 |
| Chain | Residue |
| A | GLN44 |
| A | ADP1301 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1304 |
| Chain | Residue |
| A | ARG23 |
| A | ARG136 |
| A | THR137 |
| A | LYS140 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGRGQFSEVYrAaclldgvp..........VALK |
| Chain | Residue | Details |
| A | ILE40-LYS63 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. VmHrDIKpaNVFI |
| Chain | Residue | Details |
| A | VAL157-ILE169 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP161 | |
| Chain | Residue | Details |
| A | ILE40 | |
| A | LYS63 | |
| Chain | Residue | Details |
| A | TYR97 | |
| Chain | Residue | Details |
| A | SER195 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ASP161 | |
| A | ALA165 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ASP161 | |
| A | LYS163 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | THR199 | |
| A | ASP161 | |
| A | LYS163 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ASN166 | |
| A | ASP161 | |
| A | LYS163 | |
