2WNR

The structure of Methanothermobacter thermautotrophicus exosome core assembly

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000177	cellular_component	cytoplasmic exosome (RNase complex)
A	0000178	cellular_component	exosome (RNase complex)
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0006401	biological_process	RNA catabolic process
A	0016075	biological_process	rRNA catabolic process
A	0035925	molecular_function	mRNA 3'-UTR AU-rich region binding
B	0000175	molecular_function	3'-5'-RNA exonuclease activity
B	0000177	cellular_component	cytoplasmic exosome (RNase complex)
B	0000178	cellular_component	exosome (RNase complex)
B	0000956	biological_process	nuclear-transcribed mRNA catabolic process
B	0003723	molecular_function	RNA binding
B	0004518	molecular_function	nuclease activity
B	0004527	molecular_function	exonuclease activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0006401	biological_process	RNA catabolic process
B	0010467	biological_process	gene expression
B	0016075	biological_process	rRNA catabolic process
B	0016787	molecular_function	hydrolase activity
B	0016896	molecular_function	RNA exonuclease activity, producing 5'-phosphomonoesters
B	1902494	cellular_component	catalytic complex
C	0000177	cellular_component	cytoplasmic exosome (RNase complex)
C	0000178	cellular_component	exosome (RNase complex)
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0006401	biological_process	RNA catabolic process
C	0016075	biological_process	rRNA catabolic process
C	0035925	molecular_function	mRNA 3'-UTR AU-rich region binding
D	0000175	molecular_function	3'-5'-RNA exonuclease activity
D	0000177	cellular_component	cytoplasmic exosome (RNase complex)
D	0000178	cellular_component	exosome (RNase complex)
D	0000956	biological_process	nuclear-transcribed mRNA catabolic process
D	0003723	molecular_function	RNA binding
D	0004518	molecular_function	nuclease activity
D	0004527	molecular_function	exonuclease activity
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0006401	biological_process	RNA catabolic process
D	0010467	biological_process	gene expression
D	0016075	biological_process	rRNA catabolic process
D	0016787	molecular_function	hydrolase activity
D	0016896	molecular_function	RNA exonuclease activity, producing 5'-phosphomonoesters
D	1902494	cellular_component	catalytic complex
E	0000177	cellular_component	cytoplasmic exosome (RNase complex)
E	0000178	cellular_component	exosome (RNase complex)
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0006401	biological_process	RNA catabolic process
E	0016075	biological_process	rRNA catabolic process
E	0035925	molecular_function	mRNA 3'-UTR AU-rich region binding
F	0000175	molecular_function	3'-5'-RNA exonuclease activity
F	0000177	cellular_component	cytoplasmic exosome (RNase complex)
F	0000178	cellular_component	exosome (RNase complex)
F	0000956	biological_process	nuclear-transcribed mRNA catabolic process
F	0003723	molecular_function	RNA binding
F	0004518	molecular_function	nuclease activity
F	0004527	molecular_function	exonuclease activity
F	0005515	molecular_function	protein binding
F	0005737	cellular_component	cytoplasm
F	0006401	biological_process	RNA catabolic process
F	0010467	biological_process	gene expression
F	0016075	biological_process	rRNA catabolic process
F	0016787	molecular_function	hydrolase activity
F	0016896	molecular_function	RNA exonuclease activity, producing 5'-phosphomonoesters
F	1902494	cellular_component	catalytic complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 B 1237

Chain	Residue
B	ARG97
B	GLY135
B	THR136
B	ARG137

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site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 F 1238

Chain	Residue
F	HOH2025
F	HOH2026
F	HOH2027
F	ARG97
F	GLY134
F	GLY135
F	THR136
F	ARG137

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 D 1237

Chain	Residue
D	ARG97
D	GLY135
D	THR136
D	ARG137

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