2WNC

Crystal structure of Aplysia ACHBP in complex with tropisetron

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE TKT A 300

Chain	Residue
A	TYR93
E	ILE118
A	SER146
A	TRP147
A	CYS190
A	TYR195
A	HOH2140
E	TYR55
E	GLN57
E	MET116

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site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE TKT B 300

Chain	Residue
A	TYR55
A	GLN57
A	ILE118
A	HOH2018
B	TYR93
B	SER146
B	TRP147
B	CYS190
B	TYR195

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site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE TKT C 300

Chain	Residue
B	GLN57
C	TYR93
C	SER146
C	TRP147
C	CYS190
C	CYS191
C	TYR195

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site_id	AC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE TKT D 300

Chain	Residue
C	TYR55
C	GLN57
C	MET116
C	ILE118
D	SER146
D	TRP147
D	TYR188
D	CYS190
D	TYR195
D	HOH2137

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site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE TKT E 300

Chain	Residue
D	GLN57
E	TYR93
E	SER146
E	TRP147
E	CYS190
E	CYS191
E	TYR195

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