2WLG
Crystallographic analysis of the polysialic acid O-acetyltransferase OatWY
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0008374 | molecular_function | O-acyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0050208 | molecular_function | polysialic-acid O-acetyltransferase activity |
| A | 0070207 | biological_process | protein homotrimerization |
| B | 0005829 | cellular_component | cytosol |
| B | 0008374 | molecular_function | O-acyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0050208 | molecular_function | polysialic-acid O-acetyltransferase activity |
| B | 0070207 | biological_process | protein homotrimerization |
| C | 0005829 | cellular_component | cytosol |
| C | 0008374 | molecular_function | O-acyltransferase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0050208 | molecular_function | polysialic-acid O-acetyltransferase activity |
| C | 0070207 | biological_process | protein homotrimerization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE SOP C 1216 |
| Chain | Residue |
| B | MET108 |
| B | VAL189 |
| B | LYS190 |
| B | ACT1215 |
| C | ARG116 |
| C | ASP119 |
| C | HIS121 |
| C | ASN133 |
| C | LYS154 |
| C | TYR171 |
| C | EDO1219 |
| B | ALA110 |
| C | EDO1221 |
| C | HOH2057 |
| C | HOH2103 |
| C | HOH2104 |
| B | TRP145 |
| B | GLY147 |
| B | ARG148 |
| B | GLY165 |
| B | SER166 |
| B | VAL180 |
| B | GLY183 |
| site_id | AC2 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE SOP A 1216 |
| Chain | Residue |
| A | ARG116 |
| A | ASP119 |
| A | HIS121 |
| A | ILE123 |
| A | ASN133 |
| A | LYS154 |
| A | TYR171 |
| A | SER184 |
| A | PRO185 |
| A | EDO1218 |
| A | EDO1220 |
| A | HOH2097 |
| A | HOH2110 |
| A | HOH2114 |
| A | HOH2131 |
| A | HOH2132 |
| A | HOH2133 |
| C | MET108 |
| C | ALA110 |
| C | TRP145 |
| C | ARG148 |
| C | GLY165 |
| C | SER166 |
| C | GLY183 |
| C | VAL189 |
| C | LYS190 |
| C | ASN192 |
| C | HOH2075 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT C 1217 |
| Chain | Residue |
| A | HOH2134 |
| C | ALA110 |
| C | HIS111 |
| C | ARG148 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT C 1218 |
| Chain | Residue |
| A | HOH2082 |
| C | ARG197 |
| C | LYS198 |
| C | MET199 |
| C | TYR200 |
| C | HOH2107 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT B 1215 |
| Chain | Residue |
| B | ALA110 |
| B | HIS111 |
| B | ARG148 |
| C | SOP1216 |
| C | EDO1219 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO A 1217 |
| Chain | Residue |
| A | ASN34 |
| A | ASN35 |
| A | SER36 |
| A | ASN56 |
| A | ILE57 |
| A | THR58 |
| A | GLN81 |
| A | LYS100 |
| A | HOH2053 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 1218 |
| Chain | Residue |
| A | HIS121 |
| A | SOP1216 |
| A | HOH2134 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1219 |
| Chain | Residue |
| A | THR14 |
| A | ASN16 |
| A | SER36 |
| A | VAL37 |
| A | PHE60 |
| A | GLN83 |
| A | HOH2135 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 1219 |
| Chain | Residue |
| B | ACT1215 |
| C | THR94 |
| C | ARG116 |
| C | MET120 |
| C | SOP1216 |
| C | HOH2108 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1220 |
| Chain | Residue |
| A | SER184 |
| A | SOP1216 |
| A | HOH2123 |
| C | HIS167 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1216 |
| Chain | Residue |
| A | MET199 |
| B | ALA96 |
| B | GLU97 |
| B | HOH2008 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 1220 |
| Chain | Residue |
| C | LEU170 |
| C | TYR171 |
| C | LYS172 |
| C | PHE174 |
| C | ALA186 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 1217 |
| Chain | Residue |
| B | ASN133 |
| B | LYS154 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 1221 |
| Chain | Residue |
| A | GLY147 |
| A | SER166 |
| A | HOH2136 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1222 |
| Chain | Residue |
| A | TYR6 |
| A | ASN13 |
| A | THR14 |
| A | ILE15 |
| A | LYS105 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1223 |
| Chain | Residue |
| A | HIS75 |
| A | ALA96 |
| A | GLU97 |
| A | HOH2138 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 1221 |
| Chain | Residue |
| B | GLY183 |
| B | SER184 |
| B | HOH2035 |
| C | SER184 |
| C | PRO185 |
| C | SOP1216 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1224 |
| Chain | Residue |
| A | LYS136 |
| A | LYS154 |
| A | GLY155 |
| A | TYR171 |
| A | LYS172 |
| A | SER173 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19525232 |
| Chain | Residue | Details |
| A | ASP119 | |
| B | SER166 | |
| B | TYR171 | |
| B | LYS190 | |
| C | ASP119 | |
| C | ARG148 | |
| C | LYS154 | |
| C | SER166 | |
| C | TYR171 | |
| C | LYS190 | |
| A | ARG148 | |
| A | LYS154 | |
| A | SER166 | |
| A | TYR171 | |
| A | LYS190 | |
| B | ASP119 | |
| B | ARG148 | |
| B | LYS154 |
