2WL3
crystal structure of catechol 2,3-dioxygenase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0006725 | biological_process | obsolete cellular aromatic compound metabolic process |
| A | 0008198 | molecular_function | ferrous iron binding |
| A | 0019439 | biological_process | obsolete aromatic compound catabolic process |
| A | 0042178 | biological_process | xenobiotic catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051213 | molecular_function | dioxygenase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0006725 | biological_process | obsolete cellular aromatic compound metabolic process |
| B | 0008198 | molecular_function | ferrous iron binding |
| B | 0019439 | biological_process | obsolete aromatic compound catabolic process |
| B | 0042178 | biological_process | xenobiotic catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051213 | molecular_function | dioxygenase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0005506 | molecular_function | iron ion binding |
| C | 0006725 | biological_process | obsolete cellular aromatic compound metabolic process |
| C | 0008198 | molecular_function | ferrous iron binding |
| C | 0019439 | biological_process | obsolete aromatic compound catabolic process |
| C | 0042178 | biological_process | xenobiotic catabolic process |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051213 | molecular_function | dioxygenase activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0005506 | molecular_function | iron ion binding |
| D | 0006725 | biological_process | obsolete cellular aromatic compound metabolic process |
| D | 0008198 | molecular_function | ferrous iron binding |
| D | 0019439 | biological_process | obsolete aromatic compound catabolic process |
| D | 0042178 | biological_process | xenobiotic catabolic process |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0051213 | molecular_function | dioxygenase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FE A 1289 |
| Chain | Residue |
| A | HIS149 |
| A | HIS212 |
| A | TYR253 |
| A | GLU263 |
| A | HOH2046 |
| A | HOH2072 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 1290 |
| Chain | Residue |
| C | HOH2016 |
| C | HOH2017 |
| A | PRO111 |
| A | ASP155 |
| A | HOH2048 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 1291 |
| Chain | Residue |
| A | HIS227 |
| A | ARG231 |
| A | VAL237 |
| A | GLN240 |
| A | ILE241 |
| A | GLU288 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL A 1292 |
| Chain | Residue |
| A | ASP94 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE B 1288 |
| Chain | Residue |
| B | HIS149 |
| B | HIS212 |
| B | TYR253 |
| B | GLU263 |
| B | HOH2059 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 1289 |
| Chain | Residue |
| B | ASP94 |
| B | ALA97 |
| B | VAL102 |
| B | LEU103 |
| B | LYS176 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE C 1286 |
| Chain | Residue |
| C | HIS149 |
| C | HIS212 |
| C | TYR253 |
| C | GLU263 |
| C | HOH2048 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL C 1287 |
| Chain | Residue |
| C | LYS176 |
| C | VAL184 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FE D 1287 |
| Chain | Residue |
| D | HIS149 |
| D | HIS212 |
| D | TYR253 |
| D | GLU263 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL D 1288 |
| Chain | Residue |
| D | ASP94 |
| D | VAL102 |
| D | LYS176 |
Functional Information from PROSITE/UniProt
| site_id | PS00082 |
| Number of Residues | 22 |
| Details | EXTRADIOL_DIOXYGENAS Extradiol ring-cleavage dioxygenases signature. GkHsndealtFYcaNPsGwlwE |
| Chain | Residue | Details |
| A | GLY242-GLU263 |
