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2WKI

Crystal structure of the OXA-10 K70C mutant at pH 7.0

Functional Information from GO Data
ChainGOidnamespacecontents
A0008658molecular_functionpenicillin binding
B0008658molecular_functionpenicillin binding
Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE SO4 A 1265
ChainResidue
ASER115
ATHR206
AGLY207
APHE208
AARG250
AHOH2145
AHOH2146

site_idAC2
Number of Residues2
DetailsBINDING SITE FOR RESIDUE SO4 A 1266
ChainResidue
AARG160
AHOH2147

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A 1267
ChainResidue
ALYS134
ALYS138
ALYS152
AHOH2085

site_idAC4
Number of Residues8
DetailsBINDING SITE FOR RESIDUE GOL A 1268
ChainResidue
AGLU199
AGLU227
AGLU229
AGOL1269
AHOH2148
BTHR107
BARG109
BGLY110

site_idAC5
Number of Residues8
DetailsBINDING SITE FOR RESIDUE GOL A 1269
ChainResidue
APRO198
AGLU199
AGLU229
AGOL1268
BARG104
BLEU106
BGLY110
BVAL114

site_idAC6
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO A 1270
ChainResidue
ASER21
ASER48
AVAL164
AGLU168
AHOH2149

site_idAC7
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO A 1271
ChainResidue
AALA98
AGLU129
AILE146
AGLY149
AILE150

site_idAC8
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO A 1272
ChainResidue
AARG125
AGLY128
AGLU129
AHOH2064
AHOH2069
AHOH2150

site_idAC9
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO A 1273
ChainResidue
APHE139
AGLU168
APHE169
ASER172
AHOH2151
AHOH2152

site_idBC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO A 1274
ChainResidue
ATHR194
AGLU195
ATRP222
ALYS251
AHOH2111

site_idBC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO A 1275
ChainResidue
AARG131
ALYS134
ATYR135
ALYS152
AGLU156
AHOH2031

site_idBC3
Number of Residues7
DetailsBINDING SITE FOR RESIDUE SO4 B 1266
ChainResidue
BSER115
BTHR206
BGLY207
BPHE208
BARG250
BHOH2128
BHOH2129

site_idBC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE GOL B 1267
ChainResidue
BARG131
BLYS134
BTYR135
BHOH2130

site_idBC5
Number of Residues11
DetailsBINDING SITE FOR RESIDUE GOL B 1268
ChainResidue
ATHR107
AARG109
AGLY110
BGLU199
BTYR200
BLEU201
BGLU227
BGLU229
BHOH2099
BHOH2108
BHOH2131

site_idBC6
Number of Residues3
DetailsBINDING SITE FOR RESIDUE GOL B 1269
ChainResidue
BARG250
BLYS251
BHOH2132

site_idBC7
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO B 1270
ChainResidue
BPHE139
BGLU168
BSER172
BHOH2133

site_idBC8
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO B 1271
ChainResidue
BTHR194
BTRP222
BLYS251
BHOH2134

site_idBC9
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO B 1272
ChainResidue
BHOH2126
BLYS45
BTYR233
BGLU261
BILE263

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: Acyl-ester intermediate
ChainResidueDetails
ASER67
BSER67

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
ALYS205
BLYS205

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: N6-carboxylysine => ECO:0000269|PubMed:11188693
ChainResidueDetails
ACYS70
BCYS70

226707

PDB entries from 2024-10-30

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