2WK2

Chitinase A from Serratia marcescens ATCC990 in complex with Chitotrio-thiazoline dithioamide.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000272	biological_process	polysaccharide catabolic process
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0004568	molecular_function	chitinase activity
A	0005576	cellular_component	extracellular region
A	0005975	biological_process	carbohydrate metabolic process
A	0006032	biological_process	chitin catabolic process
A	0008061	molecular_function	chitin binding
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds

Functional Information from PROSITE/UniProt

site_id	PS01095
Number of Residues	9
Details	GH18_1 Glycosyl hydrolases family 18 (GH18) active site signature. FDGVDIDwE

Chain	Residue	Details
A	PHE307-GLU315

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000255|PROSITE-ProRule:PRU01258

Chain	Residue	Details
A	GLU315

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	4
Details	M-CSA 478

Chain	Residue	Details
A	ASP311	electrostatic stabiliser
A	ASP313	steric role
A	GLU315	proton shuttle (general acid/base)
A	TYR390	electrostatic destabiliser

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