Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0006805 | biological_process | xenobiotic metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030855 | biological_process | epithelial cell differentiation |
| A | 0070062 | cellular_component | extracellular exosome |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006749 | biological_process | glutathione metabolic process |
| B | 0006805 | biological_process | xenobiotic metabolic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0030855 | biological_process | epithelial cell differentiation |
| B | 0070062 | cellular_component | extracellular exosome |
| C | 0004364 | molecular_function | glutathione transferase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006749 | biological_process | glutathione metabolic process |
| C | 0006805 | biological_process | xenobiotic metabolic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0030855 | biological_process | epithelial cell differentiation |
| C | 0070062 | cellular_component | extracellular exosome |
| D | 0004364 | molecular_function | glutathione transferase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006749 | biological_process | glutathione metabolic process |
| D | 0006805 | biological_process | xenobiotic metabolic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0030855 | biological_process | epithelial cell differentiation |
| D | 0070062 | cellular_component | extracellular exosome |
| E | 0004364 | molecular_function | glutathione transferase activity |
| E | 0005515 | molecular_function | protein binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005829 | cellular_component | cytosol |
| E | 0006749 | biological_process | glutathione metabolic process |
| E | 0006805 | biological_process | xenobiotic metabolic process |
| E | 0016740 | molecular_function | transferase activity |
| E | 0030855 | biological_process | epithelial cell differentiation |
| E | 0070062 | cellular_component | extracellular exosome |
| F | 0004364 | molecular_function | glutathione transferase activity |
| F | 0005515 | molecular_function | protein binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005829 | cellular_component | cytosol |
| F | 0006749 | biological_process | glutathione metabolic process |
| F | 0006805 | biological_process | xenobiotic metabolic process |
| F | 0016740 | molecular_function | transferase activity |
| F | 0030855 | biological_process | epithelial cell differentiation |
| F | 0070062 | cellular_component | extracellular exosome |
| G | 0004364 | molecular_function | glutathione transferase activity |
| G | 0005515 | molecular_function | protein binding |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0005829 | cellular_component | cytosol |
| G | 0006749 | biological_process | glutathione metabolic process |
| G | 0006805 | biological_process | xenobiotic metabolic process |
| G | 0016740 | molecular_function | transferase activity |
| G | 0030855 | biological_process | epithelial cell differentiation |
| G | 0070062 | cellular_component | extracellular exosome |
| H | 0004364 | molecular_function | glutathione transferase activity |
| H | 0005515 | molecular_function | protein binding |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0005829 | cellular_component | cytosol |
| H | 0006749 | biological_process | glutathione metabolic process |
| H | 0006805 | biological_process | xenobiotic metabolic process |
| H | 0016740 | molecular_function | transferase activity |
| H | 0030855 | biological_process | epithelial cell differentiation |
| H | 0070062 | cellular_component | extracellular exosome |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GSH A 230 |
| Chain | Residue |
| A | TYR9 |
| A | HOH2080 |
| B | ASP101 |
| B | ARG131 |
| A | ARG15 |
| A | ARG45 |
| A | GLN54 |
| A | VAL55 |
| A | PRO56 |
| A | GLN67 |
| A | THR68 |
| A | PHE220 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GSH B 230 |
| Chain | Residue |
| A | ASP101 |
| A | ARG131 |
| B | TYR9 |
| B | ARG15 |
| B | ARG45 |
| B | GLN54 |
| B | VAL55 |
| B | GLN67 |
| B | THR68 |
| B | PHE220 |
| B | HOH2090 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GSH C 230 |
| Chain | Residue |
| C | ARG45 |
| C | GLN54 |
| C | VAL55 |
| C | GLN67 |
| C | THR68 |
| C | PHE220 |
| D | ASP101 |
| D | ARG131 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GSH D 230 |
| Chain | Residue |
| C | ASP101 |
| C | ARG131 |
| D | TYR9 |
| D | ARG15 |
| D | ARG45 |
| D | GLN54 |
| D | VAL55 |
| D | GLN67 |
| D | THR68 |
| D | PHE220 |
| D | HOH2029 |
| D | HOH2077 |
| D | HOH2078 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GSH E 230 |
| Chain | Residue |
| E | TYR9 |
| E | ARG45 |
| E | GLN54 |
| E | VAL55 |
| E | GLN67 |
| E | THR68 |
| E | PHE220 |
| E | HOH2028 |
| E | HOH2091 |
| E | HOH2092 |
| F | ASP101 |
| F | ARG131 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GSH F 230 |
| Chain | Residue |
| E | ASP101 |
| E | ARG131 |
| F | TYR9 |
| F | ARG15 |
| F | ARG45 |
| F | GLN54 |
| F | VAL55 |
| F | GLN67 |
| F | THR68 |
| F | PHE220 |
| F | HOH2016 |
| F | HOH2017 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GSH G 230 |
| Chain | Residue |
| G | TYR9 |
| G | ARG15 |
| G | ARG45 |
| G | GLN54 |
| G | VAL55 |
| G | PRO56 |
| G | GLN67 |
| G | THR68 |
| G | PHE220 |
| G | HOH2039 |
| H | ASP101 |
| H | ARG131 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GSH H 230 |
| Chain | Residue |
| G | ASP101 |
| G | ARG131 |
| H | TYR9 |
| H | ARG15 |
| H | ARG45 |
| H | GLN53 |
| H | GLN54 |
| H | VAL55 |
| H | GLN67 |
| H | THR68 |
| H | HOH2011 |
| H | HOH2047 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 32 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20083122 |
| Chain | Residue | Details |
| A | TYR9 | |
| C | ARG45 | |
| C | GLN54 | |
| C | GLN67 | |
| D | TYR9 | |
| D | ARG45 | |
| D | GLN54 | |
| D | GLN67 | |
| E | TYR9 | |
| E | ARG45 | |
| E | GLN54 | |
| A | ARG45 | |
| E | GLN67 | |
| F | TYR9 | |
| F | ARG45 | |
| F | GLN54 | |
| F | GLN67 | |
| G | TYR9 | |
| G | ARG45 | |
| G | GLN54 | |
| G | GLN67 | |
| H | TYR9 | |
| A | GLN54 | |
| H | ARG45 | |
| H | GLN54 | |
| H | GLN67 | |
| A | GLN67 | |
| B | TYR9 | |
| B | ARG45 | |
| B | GLN54 | |
| B | GLN67 | |
| C | TYR9 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | MOD_RES: N-acetylalanine => ECO:0000250|UniProtKB:P30115 |
| Chain | Residue | Details |
| A | ALA2 | |
| B | ALA2 | |
| C | ALA2 | |
| D | ALA2 | |
| E | ALA2 | |
| F | ALA2 | |
| G | ALA2 | |
| H | ALA2 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:P30115 |
| Chain | Residue | Details |
| A | LYS4 | |
| B | LYS4 | |
| C | LYS4 | |
| D | LYS4 | |
| E | LYS4 | |
| F | LYS4 | |
| G | LYS4 | |
| H | LYS4 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| A | TYR9 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| B | TYR9 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| C | TYR9 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| D | TYR9 |
| site_id | CSA5 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| E | TYR9 |
| site_id | CSA6 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| F | TYR9 |
| site_id | CSA7 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| G | TYR9 |
| site_id | CSA8 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| H | TYR9 |
