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2WIW

Crystal structures of Holliday junction resolvases from Archaeoglobus fulgidus bound to DNA substrate

Functional Information from GO Data
ChainGOidnamespacecontents
A0000287molecular_functionmagnesium ion binding
A0003676molecular_functionnucleic acid binding
A0003677molecular_functionDNA binding
A0004519molecular_functionendonuclease activity
A0006281biological_processDNA repair
A0006310biological_processDNA recombination
A0008821molecular_functioncrossover junction DNA endonuclease activity
A0046872molecular_functionmetal ion binding
B0000287molecular_functionmagnesium ion binding
B0003676molecular_functionnucleic acid binding
B0003677molecular_functionDNA binding
B0004519molecular_functionendonuclease activity
B0006281biological_processDNA repair
B0006310biological_processDNA recombination
B0008821molecular_functioncrossover junction DNA endonuclease activity
B0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues8
DetailsBINDING SITE FOR RESIDUE HEZ A 1125
ChainResidue
ALEU13
ATRP17
AALA22
AALA23
AHOH2086
BPHE34
BPRO35
BHOH2004

site_idAC2
Number of Residues2
DetailsBINDING SITE FOR RESIDUE HEZ A 1126
ChainResidue
AHOH2088
AVAL97

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE HEZ D 1011
ChainResidue
CDC9
DDG3
DDA4
DDT5
DHOH2011

site_idAC4
Number of Residues6
DetailsBINDING SITE FOR RESIDUE HEZ B 1131
ChainResidue
BGLU57
BLEU58
BPRO88
BLYS90
BGLU111
CDA6

site_idAC5
Number of Residues5
DetailsBINDING SITE FOR RESIDUE GOL B 1132
ChainResidue
BARG102
BTHR103
BLYS105
BASN106
BHOH2066

site_idAC6
Number of Residues3
DetailsBINDING SITE FOR RESIDUE GOL A 1127
ChainResidue
AGLU104
AGLY117
AGLU122

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_01490
ChainResidueDetails
ASER29
BSER29

site_idSWS_FT_FI2
Number of Residues6
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01490
ChainResidueDetails
AGLU9
AASP38
AGLU51
BGLU9
BASP38
BGLU51

site_idSWS_FT_FI3
Number of Residues2
DetailsSITE: Transition state stabilizer => ECO:0000255
ChainResidueDetails
ALYS53
BLYS53

226707

PDB entries from 2024-10-30

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