2WHG
Crystal Structure of the Di-Zinc Metallo-beta-lactamase VIM-4 from Pseudomonas aeruginosa
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008800 | molecular_function | beta-lactamase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0017001 | biological_process | antibiotic catabolic process |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0008800 | molecular_function | beta-lactamase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0017001 | biological_process | antibiotic catabolic process |
| B | 0042597 | cellular_component | periplasmic space |
| B | 0046677 | biological_process | response to antibiotic |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1262 |
| Chain | Residue |
| A | ASP118 |
| A | CYS198 |
| A | HIS240 |
| A | FLC1264 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1263 |
| Chain | Residue |
| A | HIS114 |
| A | HIS116 |
| A | HIS179 |
| A | FLC1264 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1262 |
| Chain | Residue |
| B | HIS116 |
| B | HIS179 |
| B | FLC1264 |
| B | HIS114 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1263 |
| Chain | Residue |
| B | ASP118 |
| B | CYS198 |
| B | HIS240 |
| B | FLC1264 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE FLC A 1264 |
| Chain | Residue |
| A | PHE62 |
| A | TRP87 |
| A | HIS114 |
| A | HIS116 |
| A | ASP118 |
| A | HIS179 |
| A | CYS198 |
| A | ARG205 |
| A | ASN210 |
| A | HIS240 |
| A | ZN1262 |
| A | ZN1263 |
| A | HOH2086 |
| A | HOH2230 |
| A | HOH2280 |
| A | HOH2281 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE FLC B 1264 |
| Chain | Residue |
| B | PHE62 |
| B | TRP87 |
| B | HIS114 |
| B | HIS116 |
| B | ASP118 |
| B | HIS179 |
| B | CYS198 |
| B | ARG205 |
| B | ASN210 |
| B | HIS240 |
| B | ZN1262 |
| B | ZN1263 |
| B | HOH2079 |
| B | HOH2154 |
