Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019430 | biological_process | removal of superoxide radicals |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019430 | biological_process | removal of superoxide radicals |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 33 |
| Details | BINDING SITE FOR RESIDUE FAD A 400 |
| Chain | Residue |
| A | ILE16 |
| A | ALA44 |
| A | ILE47 |
| A | ALA48 |
| A | GLY51 |
| A | GLN52 |
| A | LEU53 |
| A | ASN61 |
| A | VAL94 |
| A | THR122 |
| A | GLY123 |
| A | GLY17 |
| A | ALA124 |
| A | CYS148 |
| A | GLY292 |
| A | ASP293 |
| A | ARG300 |
| A | GLN301 |
| A | ALA302 |
| A | HOH2004 |
| A | HOH2005 |
| A | HOH2013 |
| A | SER18 |
| A | HOH2030 |
| A | HOH2031 |
| A | HOH2032 |
| A | HOH2033 |
| A | GLY19 |
| A | PRO20 |
| A | ALA21 |
| A | TYR28 |
| A | PHE39 |
| A | GLY41 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FLC A 401 |
| Chain | Residue |
| A | ILE163 |
| A | HIS187 |
| A | ARG188 |
| A | ARG189 |
| A | ILE253 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE FLC A 402 |
| Chain | Residue |
| A | ASP167 |
| A | SER168 |
| A | ARG193 |
| A | GLY254 |
| A | HIS255 |
| A | LYS297 |
| A | ARG300 |
| A | HOH2034 |
| site_id | AC4 |
| Number of Residues | 34 |
| Details | BINDING SITE FOR RESIDUE FAD B 400 |
| Chain | Residue |
| B | GLY17 |
| B | SER18 |
| B | GLY19 |
| B | PRO20 |
| B | ALA21 |
| B | TYR28 |
| B | PHE39 |
| B | GLU40 |
| B | GLY41 |
| B | ALA44 |
| B | ILE47 |
| B | ALA48 |
| B | GLY51 |
| B | GLN52 |
| B | LEU53 |
| B | THR55 |
| B | THR56 |
| B | ASN61 |
| B | VAL94 |
| B | THR122 |
| B | GLY123 |
| B | ALA124 |
| B | GLY292 |
| B | ASP293 |
| B | ARG300 |
| B | GLN301 |
| B | ALA302 |
| B | HOH2002 |
| B | HOH2004 |
| B | HOH2009 |
| B | HOH2011 |
| B | HOH2012 |
| B | HOH2013 |
| B | HOH2014 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FLC B 401 |
| Chain | Residue |
| B | ILE163 |
| B | GLY164 |
| B | HIS187 |
| B | ARG188 |
| B | ARG189 |
| B | ILE253 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FLC B 402 |
| Chain | Residue |
| B | GLY166 |
| B | ASP167 |
| B | SER168 |
| B | ARG193 |
| B | HIS255 |
| B | ARG300 |
Functional Information from PROSITE/UniProt
| site_id | PS00573 |
| Number of Residues | 23 |
| Details | PYRIDINE_REDOX_2 Pyridine nucleotide-disulphide oxidoreductases class-II active site. CavCDGaapiFrnkpIaVIGGGD |
| Chain | Residue | Details |
| A | CYS145-ASP167 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1tde |
| Chain | Residue | Details |
| A | CYS145 | |
| A | CYS148 | |
| A | ASP149 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1tde |
| Chain | Residue | Details |
| B | CYS145 | |
| B | CYS148 | |
| B | ASP149 | |
