2WFR

Crystal structure of the N-terminal signalling domain of human Dhh with calcium

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007267	biological_process	cell-cell signaling
A	0007275	biological_process	multicellular organism development

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 1204

Chain	Residue
A	HIS141
A	ASP148
A	HIS183
A	HIS203

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 1205

Chain	Residue
A	GLU90
A	GLU91
A	ASP96
A	THR126
A	GLU127

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA A 1206

Chain	Residue
A	GLU91
A	GLU127
A	ASP130

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site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 1207

Chain	Residue
A	LYS88
A	ARG124
A	GLN137
A	ARG154
A	HOH2073

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 1208

Chain	Residue
A	LEU44
A	TYR45
A	ARG179
A	HOH2096

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19561611","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20519495","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2WFR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N1G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N1Q","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19561611","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20519495","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2WFQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WFR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WG3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N1G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N1Q","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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