Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004476 | molecular_function | mannose-6-phosphate isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0009298 | biological_process | GDP-mannose biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1392 |
| Chain | Residue |
| A | ARG353 |
| A | LYS354 |
| A | ASP355 |
| A | PRO375 |
| A | ASN377 |
| A | HOH2359 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1393 |
| Chain | Residue |
| A | THR278 |
| A | EDO1403 |
| A | HOH2262 |
| A | HOH2360 |
| A | LYS195 |
| A | ASP227 |
| A | SER228 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 1394 |
| Chain | Residue |
| A | SER95 |
| A | GLN97 |
| A | HOH2106 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1395 |
| Chain | Residue |
| A | ILE96 |
| A | PHE184 |
| A | SER228 |
| A | GLY229 |
| A | PHE231 |
| A | SER232 |
| A | ALA275 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1396 |
| Chain | Residue |
| A | ASN6 |
| A | LYS307 |
| A | SER308 |
| A | GLY309 |
| A | EDO1400 |
| A | HOH2364 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 1397 |
| Chain | Residue |
| A | ALA185 |
| A | ASN189 |
| A | ILE284 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1398 |
| Chain | Residue |
| A | ARG77 |
| A | VAL155 |
| A | LEU172 |
| A | PRO175 |
| A | EDO1405 |
| A | HOH2361 |
| A | HOH2362 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO A 1399 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1400 |
| Chain | Residue |
| A | ASN6 |
| A | GLY364 |
| A | EDO1396 |
| A | HOH2014 |
| A | HOH2364 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1401 |
| Chain | Residue |
| A | ALA310 |
| A | GLU311 |
| A | HIS326 |
| A | SER334 |
| A | HOH2315 |
| A | HOH2365 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1402 |
| Chain | Residue |
| A | ASN104 |
| A | LYS111 |
| A | TYR126 |
| A | GLU286 |
| A | ASN290 |
| A | HOH2366 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1403 |
| Chain | Residue |
| A | MET190 |
| A | GLN191 |
| A | LYS195 |
| A | EDO1393 |
| A | HOH2226 |
| A | HOH2229 |
| A | HOH2368 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1404 |
| Chain | Residue |
| A | GLN97 |
| A | HIS99 |
| A | GLU134 |
| A | LEU249 |
| A | HIS255 |
| A | GLU264 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1405 |
| Chain | Residue |
| A | ASN76 |
| A | EDO1398 |
| A | HOH2093 |
| A | HOH2368 |
| A | HOH2369 |
| A | HOH2370 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1406 |
| Chain | Residue |
| A | ALA298 |
| A | GLY299 |
| A | GLU300 |
| A | LEU301 |
| A | LEU302 |
| site_id | BC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1407 |
| Chain | Residue |
| A | ALA40 |
| A | PRO42 |
| A | ARG59 |
| A | GLU80 |
| A | LEU81 |
| A | ASN268 |
| A | HOH2372 |
Functional Information from PROSITE/UniProt
| site_id | PS00965 |
| Number of Residues | 9 |
| Details | PMI_I_1 Phosphomannose isomerase type I signature 1. YkDpNHKPE |
| Chain | Residue | Details |
| A | TYR126-GLU134 | |
| site_id | PS00966 |
| Number of Residues | 26 |
| Details | PMI_I_2 Phosphomannose isomerase type I signature 2. HAYLqGvaLEvMAnSDNvLRAGlTPK |
| Chain | Residue | Details |
| A | HIS255-LYS280 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250 |
| Chain | Residue | Details |
| A | ARG274 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | GLN97 | |
| A | HIS99 | |
| A | GLU134 | |
| A | HIS255 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pmi |
| Chain | Residue | Details |
| A | GLN97 | |
| A | GLU264 | |
| A | ARG274 | |
