2WBI
Crystal structure of human acyl-CoA dehydrogenase 11
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE FAD A 600 |
| Chain | Residue |
| A | PHE152 |
| A | VAL397 |
| A | LEU400 |
| A | PRO404 |
| A | GLU406 |
| A | VAL407 |
| B | ARG305 |
| B | PHE308 |
| B | LEU312 |
| B | HIS315 |
| B | GLU316 |
| A | MET154 |
| B | GLN375 |
| B | VAL376 |
| B | GLY378 |
| B | GLY379 |
| A | THR155 |
| A | ALA160 |
| A | SER161 |
| A | SER162 |
| A | TRP186 |
| A | SER188 |
| A | HIS246 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE FAD B 600 |
| Chain | Residue |
| A | ARG305 |
| A | PHE308 |
| A | LEU312 |
| A | HIS315 |
| A | GLU316 |
| A | GLN375 |
| A | VAL376 |
| A | GLY378 |
| A | GLY379 |
| B | PHE152 |
| B | MET154 |
| B | THR155 |
| B | ALA160 |
| B | SER161 |
| B | SER162 |
| B | TRP186 |
| B | SER188 |
| B | HIS246 |
| B | VAL397 |
| B | LEU400 |
| B | PRO404 |
| B | GLU406 |
| B | VAL407 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1427 |
| Chain | Residue |
| A | LYS310 |
| A | HIS315 |
| A | GLU316 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 B 1426 |
| Chain | Residue |
| B | LYS310 |
| B | ALA314 |
| B | HIS315 |
| B | GLU316 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE UNX A 1428 |
| Chain | Residue |
| A | ARG275 |
| A | HIS283 |
| A | ASP402 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE UNX A 1429 |
| Chain | Residue |
| A | SER188 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE UNX A 1430 |
| Chain | Residue |
| A | UNX1431 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE UNX A 1431 |
| Chain | Residue |
| A | UNX1430 |
| A | UNX1432 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE UNX A 1432 |
| Chain | Residue |
| A | ASN390 |
| A | UNX1431 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE UNX B 1427 |
| Chain | Residue |
| B | ARG275 |
| B | ASP402 |
| B | UNX1428 |
| site_id | BC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE UNX B 1428 |
| Chain | Residue |
| B | UNX1427 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE UNX B 1429 |
| Chain | Residue |
| B | ASP240 |
| B | UNX1430 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE UNX B 1430 |
| Chain | Residue |
| B | ASN390 |
| B | UNX1429 |
| B | UNX1431 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE UNX B 1431 |
| Chain | Residue |
| B | ASN390 |
| B | UNX1430 |
| B | UNX1432 |
| site_id | BC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE UNX B 1432 |
| Chain | Residue |
| B | UNX1431 |
| site_id | BC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE UNX B 1434 |
| Chain | Residue |
| B | UNX1435 |
| site_id | BC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE UNX B 1435 |
| Chain | Residue |
| B | UNX1434 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 30 |
| Details | Binding site: {"description":"in other chain","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAY-2009","submissionDatabase":"PDB data bank","title":"Crystal structure of human acyl-CoA dehydrogenase 11.","authoringGroup":["Structural genomics consortium (SGC)"]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAY-2009","submissionDatabase":"PDB data bank","title":"Crystal structure of human acyl-CoA dehydrogenase 11.","authoringGroup":["Structural genomics consortium (SGC)"]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q80XL6","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ivh |
| Chain | Residue | Details |
| A | GLY279 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ivh |
| Chain | Residue | Details |
| B | GLY279 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ivh |
| Chain | Residue | Details |
| A | ASP402 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ivh |
| Chain | Residue | Details |
| B | ASP402 |
