2WBG
Structure of family 1 beta-glucosidase from Thermotoga maritima in complex with 3-imino-2-oxa-(+)-castanospermine
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
A | 0005829 | cellular_component | cytosol |
A | 0005975 | biological_process | carbohydrate metabolic process |
A | 0008422 | molecular_function | beta-glucosidase activity |
A | 0016052 | biological_process | carbohydrate catabolic process |
A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
A | 0030245 | biological_process | cellulose catabolic process |
A | 0102483 | molecular_function | scopolin beta-glucosidase activity |
B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
B | 0005829 | cellular_component | cytosol |
B | 0005975 | biological_process | carbohydrate metabolic process |
B | 0008422 | molecular_function | beta-glucosidase activity |
B | 0016052 | biological_process | carbohydrate catabolic process |
B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
B | 0030245 | biological_process | cellulose catabolic process |
B | 0102483 | molecular_function | scopolin beta-glucosidase activity |
C | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
C | 0005829 | cellular_component | cytosol |
C | 0005975 | biological_process | carbohydrate metabolic process |
C | 0008422 | molecular_function | beta-glucosidase activity |
C | 0016052 | biological_process | carbohydrate catabolic process |
C | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
C | 0030245 | biological_process | cellulose catabolic process |
C | 0102483 | molecular_function | scopolin beta-glucosidase activity |
D | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
D | 0005829 | cellular_component | cytosol |
D | 0005975 | biological_process | carbohydrate metabolic process |
D | 0008422 | molecular_function | beta-glucosidase activity |
D | 0016052 | biological_process | carbohydrate catabolic process |
D | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
D | 0030245 | biological_process | cellulose catabolic process |
D | 0102483 | molecular_function | scopolin beta-glucosidase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE LGS A 1446 |
Chain | Residue |
A | GLN20 |
A | TRP398 |
A | GLU405 |
A | TRP406 |
A | HOH2410 |
A | HOH2411 |
A | HIS121 |
A | ASN165 |
A | GLU166 |
A | TYR295 |
A | SER296 |
A | HIS298 |
A | TRP324 |
A | GLU351 |
site_id | AC2 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE LGS B 1446 |
Chain | Residue |
B | GLN20 |
B | HIS121 |
B | ASN165 |
B | GLU166 |
B | TYR295 |
B | HIS298 |
B | TRP324 |
B | GLU351 |
B | TRP398 |
B | GLU405 |
B | TRP406 |
B | HOH2190 |
B | HOH2379 |
site_id | AC3 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE LGS C 1446 |
Chain | Residue |
C | GLN20 |
C | HIS121 |
C | ASN165 |
C | GLU166 |
C | TYR295 |
C | SER296 |
C | HIS298 |
C | TRP324 |
C | GLU351 |
C | TRP398 |
C | GLU405 |
C | TRP406 |
C | PHE414 |
C | HOH2259 |
C | HOH2519 |
site_id | AC4 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE LGS D 1446 |
Chain | Residue |
D | GLN20 |
D | HIS121 |
D | ASN165 |
D | GLU166 |
D | TYR295 |
D | HIS298 |
D | TRP324 |
D | GLU351 |
D | TRP398 |
D | GLU405 |
D | TRP406 |
D | PHE414 |
D | HOH2454 |
D | HOH2455 |
site_id | AC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ACT C 1447 |
Chain | Residue |
C | TRP168 |
C | ASN246 |
C | HOH2520 |
C | HOH2521 |
C | HOH2522 |
Functional Information from PROSITE/UniProt
site_id | PS00572 |
Number of Residues | 9 |
Details | GLYCOSYL_HYDROL_F1_1 Glycosyl hydrolases family 1 active site. VYITENGAA |
Chain | Residue | Details |
A | VAL347-ALA355 |
site_id | PS00653 |
Number of Residues | 15 |
Details | GLYCOSYL_HYDROL_F1_2 Glycosyl hydrolases family 1 N-terminal signature. FlWGvAtASYQiEgS |
Chain | Residue | Details |
A | PHE10-SER24 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | ACT_SITE: Proton donor => ECO:0000255 |
Chain | Residue | Details |
A | GLU166 | |
B | GLU166 | |
C | GLU166 | |
D | GLU166 |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | ACT_SITE: Nucleophile => ECO:0000255|PROSITE-ProRule:PRU10055 |
Chain | Residue | Details |
A | GLU351 | |
B | GLU351 | |
C | GLU351 | |
D | GLU351 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1cbg |
Chain | Residue | Details |
A | GLU166 | |
A | ASN293 | |
A | GLU351 |
site_id | CSA2 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1cbg |
Chain | Residue | Details |
B | GLU166 | |
B | ASN293 | |
B | GLU351 |
site_id | CSA3 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1cbg |
Chain | Residue | Details |
C | GLU166 | |
C | ASN293 | |
C | GLU351 |
site_id | CSA4 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1cbg |
Chain | Residue | Details |
D | GLU166 | |
D | ASN293 | |
D | GLU351 |
site_id | CSA5 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1cbg |
Chain | Residue | Details |
A | GLU166 | |
A | GLU351 |
site_id | CSA6 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1cbg |
Chain | Residue | Details |
B | GLU166 | |
B | GLU351 |
site_id | CSA7 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1cbg |
Chain | Residue | Details |
C | GLU166 | |
C | GLU351 |
site_id | CSA8 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1cbg |
Chain | Residue | Details |
D | GLU166 | |
D | GLU351 |