2WAB

Structure of an active site mutant of a family two carbohydrate esterase from Clostridium thermocellum in complex with celluohexase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016788	molecular_function	hydrolase activity, acting on ester bonds
A	0052689	molecular_function	carboxylic ester hydrolase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	324
Details	Region: {"description":"Esterase","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Nucleophile; for esterase activity","evidences":[{"source":"PubMed","id":"19338387","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Site: {"description":"Transition state stabilizer","evidences":[{"source":"UniProtKB","id":"B3PIB0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Site: {"description":"Increases nucleophilicity of active site Ser","evidences":[{"source":"PubMed","id":"19338387","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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