2W6T
Structures of P. aeruginosa FpvA bound to heterologous pyoverdines: FpvA-Pvd(DSM50106)-Fe complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002049 | biological_process | pyoverdine biosynthetic process |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0006826 | biological_process | iron ion transport |
| A | 0009279 | cellular_component | cell outer membrane |
| A | 0015343 | molecular_function | siderophore-iron transmembrane transporter activity |
| A | 0015344 | molecular_function | siderophore uptake transmembrane transporter activity |
| A | 0015891 | biological_process | siderophore transport |
| A | 0016020 | cellular_component | membrane |
| A | 0019867 | cellular_component | outer membrane |
| A | 0033214 | biological_process | siderophore-iron import into cell |
| A | 0038023 | molecular_function | signaling receptor activity |
| B | 0002049 | biological_process | pyoverdine biosynthetic process |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0006826 | biological_process | iron ion transport |
| B | 0009279 | cellular_component | cell outer membrane |
| B | 0015343 | molecular_function | siderophore-iron transmembrane transporter activity |
| B | 0015344 | molecular_function | siderophore uptake transmembrane transporter activity |
| B | 0015891 | biological_process | siderophore transport |
| B | 0016020 | cellular_component | membrane |
| B | 0019867 | cellular_component | outer membrane |
| B | 0033214 | biological_process | siderophore-iron import into cell |
| B | 0038023 | molecular_function | signaling receptor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE N8E A 1816 |
| Chain | Residue |
| A | GLY309 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE N8E A 1817 |
| Chain | Residue |
| A | PHE809 |
| A | SER810 |
| A | THR811 |
| B | TYR769 |
| B | ALA777 |
| B | SER778 |
| B | ARG805 |
| B | PHE809 |
| B | SER810 |
| B | THR811 |
| A | ALA724 |
| A | LEU725 |
| A | TYR769 |
| A | ALA777 |
| A | SER778 |
| A | VAL779 |
| A | ARG805 |
| A | LEU807 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1818 |
| Chain | Residue |
| A | HIS424 |
| A | PRO426 |
| A | LYS447 |
| A | LYS512 |
| A | TRP515 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 B 1818 |
| Chain | Residue |
| B | HIS424 |
| B | PRO426 |
| B | LYS447 |
| B | LYS512 |
| B | TRP515 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1819 |
| Chain | Residue |
| A | ASN184 |
| A | ASP186 |
| A | ARG190 |
| A | ASN205 |
| A | LYS318 |
| A | ARG327 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1820 |
| Chain | Residue |
| A | GLU142 |
| A | ASP143 |
| A | ARG174 |
| A | ASP178 |
| A | LYS271 |
| A | HIS280 |
| A | ARG812 |
| A | PO41822 |
| A | PO41823 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 B 1819 |
| Chain | Residue |
| B | ASN184 |
| B | ASP186 |
| B | ASP187 |
| B | ARG190 |
| B | LYS318 |
| B | ARG327 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 B 1820 |
| Chain | Residue |
| B | GLU142 |
| B | ARG174 |
| B | ASP178 |
| B | HIS280 |
| B | ARG310 |
| B | ARG812 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1821 |
| Chain | Residue |
| A | HIS418 |
| A | ILE420 |
| A | LYS453 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 B 1821 |
| Chain | Residue |
| B | HIS418 |
| B | ILE420 |
| B | LYS453 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1822 |
| Chain | Residue |
| A | GLU142 |
| A | ASP143 |
| A | LYS278 |
| A | ARG812 |
| A | ASP814 |
| A | PO41820 |
| site_id | BC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1823 |
| Chain | Residue |
| A | ARG174 |
| A | ASP178 |
| A | LYS271 |
| A | HIS280 |
| A | GLU282 |
| A | GLU294 |
| A | ARG812 |
| A | PO41820 |
| site_id | BC4 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR LINKED RESIDUES C 1 to 12 |
| Chain | Residue |
| A | ASN656 |
| A | PRO657 |
| B | ARG100 |
| B | TYR200 |
| B | ARG204 |
| B | ASN228 |
| B | GLY230 |
| B | TYR231 |
| B | TRP362 |
| B | SER363 |
| B | TRP391 |
| B | MET431 |
| B | GLY432 |
| B | GLN446 |
| B | TYR448 |
| B | TRP491 |
| B | TRP599 |
| B | TYR600 |
| B | PHE795 |
| B | TYR796 |
Functional Information from PROSITE/UniProt
| site_id | PS01156 |
| Number of Residues | 18 |
| Details | TONB_DEPENDENT_REC_2 TonB-dependent receptor (TBDR) proteins signature 2. SasyGdPRnLmFSTrWdF |
| Chain | Residue | Details |
| A | SER798-PHE815 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 220 |
| Details | Domain: {"description":"TBDR plug","evidences":[{"source":"PROSITE-ProRule","id":"PRU01360","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1078 |
| Details | Domain: {"description":"TBDR beta-barrel","evidences":[{"source":"PROSITE-ProRule","id":"PRU01360","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 34 |
| Details | Motif: {"description":"TonB C-terminal box"} |
| Chain | Residue | Details |
