2W6D
BACTERIAL DYNAMIN-LIKE PROTEIN LIPID TUBE BOUND
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008053 | biological_process | mitochondrial fusion |
| A | 0008289 | molecular_function | lipid binding |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0042802 | molecular_function | identical protein binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0008053 | biological_process | mitochondrial fusion |
| B | 0008289 | molecular_function | lipid binding |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0042802 | molecular_function | identical protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE GDP A 1696 |
| Chain | Residue |
| A | LYS79 |
| A | GLN242 |
| A | SER291 |
| A | SER292 |
| A | ILE293 |
| B | GLN242 |
| B | VAL243 |
| B | ARG244 |
| B | GLU245 |
| B | SER246 |
| B | SER259 |
| A | ARG80 |
| A | GLY81 |
| A | LYS82 |
| A | SER83 |
| A | THR84 |
| A | ASN238 |
| A | ALA239 |
| A | ASP241 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CPL A 1697 |
| Chain | Residue |
| A | ALA586 |
| A | CPL1699 |
| A | CPL1700 |
| A | CPL1705 |
| A | CPL1710 |
| A | CPL3077 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CPL A 1698 |
| Chain | Residue |
| A | VAL581 |
| A | CPL1699 |
| A | CPL1700 |
| A | CPL1707 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CPL A 1699 |
| Chain | Residue |
| A | GLY582 |
| A | LEU584 |
| A | GLN585 |
| A | ALA586 |
| A | CPL1697 |
| A | CPL1698 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CPL A 1700 |
| Chain | Residue |
| A | CPL1697 |
| A | CPL1698 |
| A | CPL1710 |
| A | CPL1713 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE CPL A 1701 |
| Chain | Residue |
| A | THR414 |
| A | PHE415 |
| A | GLU416 |
| A | ASN417 |
| A | ASP418 |
| A | PHE419 |
| A | LEU420 |
| A | ASP587 |
| A | CPL1712 |
| B | LEU420 |
| B | ARG421 |
| B | GLN423 |
| B | CPL1700 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CPL A 1702 |
| Chain | Residue |
| A | PHE429 |
| A | SER433 |
| A | SER434 |
| A | CPL1706 |
| A | CPL1708 |
| A | CPL1716 |
| A | CPL1717 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CPL A 1703 |
| Chain | Residue |
| A | GLY412 |
| A | ASN413 |
| A | GLU416 |
| A | CPL1704 |
| A | CPL1715 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CPL A 1704 |
| Chain | Residue |
| A | CPL1703 |
| A | CPL1714 |
| B | CPL1705 |
| site_id | BC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE CPL A 1705 |
| Chain | Residue |
| A | PHE415 |
| A | PHE419 |
| A | LEU444 |
| A | GLN445 |
| A | PHE448 |
| A | ILE557 |
| A | GLY558 |
| A | ILE560 |
| A | ILE561 |
| A | THR562 |
| A | VAL564 |
| A | THR565 |
| A | LEU568 |
| A | ILE572 |
| A | LEU576 |
| A | LEU579 |
| A | ARG590 |
| A | CPL1697 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CPL A 1706 |
| Chain | Residue |
| A | PHE429 |
| A | CPL1702 |
| A | CPL1711 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CPL A 1707 |
| Chain | Residue |
| A | LEU577 |
| A | VAL581 |
| A | GLY582 |
| A | PHE583 |
| A | CPL1698 |
| A | CPL1710 |
| site_id | BC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE CPL A 1708 |
| Chain | Residue |
| A | GLN450 |
| A | CPL1702 |
| A | CPL1716 |
| B | CPL1704 |
| A | GLU425 |
| A | LEU426 |
| A | LYS446 |
| A | ALA447 |
| A | GLU449 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CPL A 1709 |
| Chain | Residue |
| A | LEU432 |
| A | SER433 |
| A | SER434 |
| A | GLY435 |
| A | LYS436 |
| A | CPL1710 |
| A | CPL3077 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CPL A 1710 |
| Chain | Residue |
| A | LEU579 |
| A | GLY580 |
| A | VAL581 |
| A | CPL1697 |
| A | CPL1700 |
| A | CPL1707 |
| A | CPL1709 |
| site_id | BC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CPL A 1711 |
| Chain | Residue |
| A | CPL1706 |
| A | CPL1716 |
| site_id | BC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CPL A 3094 |
| Chain | Residue |
| A | CPL3181 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CPL A 3097 |
| Chain | Residue |
| A | CPL1712 |
| A | CPL1718 |
| B | CPL1700 |
| site_id | CC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CPL A 1712 |
| Chain | Residue |
| A | CPL1701 |
| A | CPL3097 |
| site_id | CC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CPL A 3181 |
| Chain | Residue |
| A | CPL3094 |
| site_id | CC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CPL A 1713 |
| Chain | Residue |
| A | CPL1700 |
| A | CPL1717 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CPL B 1696 |
| Chain | Residue |
| B | VAL581 |
| B | GLY582 |
| B | GLN585 |
| B | CPL1709 |
| B | CPL1714 |
| site_id | CC5 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE CPL B 1697 |
| Chain | Residue |
| B | ASN441 |
| B | LEU444 |
| B | ILE561 |
| B | THR562 |
| B | VAL564 |
| B | THR565 |
| B | GLY566 |
| B | LEU568 |
| B | LEU569 |
| B | ILE572 |
| B | GLY573 |
| B | LEU576 |
| B | LEU579 |
| B | ALA586 |
| B | ASP587 |
| B | ARG590 |
| B | LEU593 |
| B | CPL1698 |
| B | CPL1714 |
| site_id | CC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CPL B 1698 |
| Chain | Residue |
| B | LYS436 |
| B | GLY580 |
| B | CPL1697 |
| B | CPL1699 |
| site_id | CC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CPL B 1699 |
| Chain | Residue |
| B | LEU577 |
| B | GLY580 |
| B | VAL581 |
| B | CPL1698 |
| B | CPL1709 |
| site_id | CC8 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE CPL B 1700 |
| Chain | Residue |
| A | ASN417 |
| A | LEU420 |
| A | ARG421 |
| A | GLN423 |
| A | CPL1701 |
| A | CPL3097 |
| B | THR414 |
| B | PHE415 |
| B | GLU416 |
| B | ASN417 |
| B | ASP418 |
| B | PHE419 |
| B | LEU420 |
| B | CPL1704 |
| site_id | CC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CPL B 1701 |
| Chain | Residue |
| B | LEU432 |
| B | SER433 |
| B | SER434 |
| B | CPL1710 |
| B | CPL1712 |
| site_id | DC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CPL B 1702 |
| Chain | Residue |
| B | PHE429 |
| B | CPL1707 |
| site_id | DC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE CPL B 1703 |
| Chain | Residue |
| B | ALA586 |
| B | ASP587 |
| B | GLN588 |
| B | ARG590 |
| B | ARG591 |
| B | VAL594 |
| B | LYS595 |
| B | LYS598 |
| B | LYS599 |
| B | VAL602 |
| B | CPL1704 |
| site_id | DC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CPL B 1704 |
| Chain | Residue |
| A | CPL1708 |
| A | CPL1718 |
| B | GLY412 |
| B | ASN413 |
| B | THR414 |
| B | PHE415 |
| B | GLU416 |
| B | ASN417 |
| B | ASP587 |
| B | ARG590 |
| B | CPL1700 |
| B | CPL1703 |
| site_id | DC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE CPL B 1705 |
| Chain | Residue |
| A | CPL1704 |
| B | PRO424 |
| B | GLU425 |
| B | LEU426 |
| B | ASN427 |
| B | LEU428 |
| B | LYS446 |
| B | ALA447 |
| B | GLU449 |
| B | CPL1711 |
| site_id | DC5 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE GDP B 1706 |
| Chain | Residue |
| A | GLN242 |
| A | VAL243 |
| A | ARG244 |
| A | GLU245 |
| A | SER246 |
| A | SER259 |
| B | LYS79 |
| B | ARG80 |
| B | GLY81 |
| B | LYS82 |
| B | SER83 |
| B | THR84 |
| B | ASN238 |
| B | ALA239 |
| B | ASP241 |
| B | GLN242 |
| B | SER291 |
| B | SER292 |
| B | ILE293 |
| site_id | DC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CPL B 1707 |
| Chain | Residue |
| B | CPL1702 |
| B | CPL1708 |
| B | CPL1711 |
| site_id | DC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CPL B 1708 |
| Chain | Residue |
| A | CPL1714 |
| B | CPL1707 |
| site_id | DC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CPL A 1714 |
| Chain | Residue |
| A | CPL1704 |
| B | CPL1708 |
| site_id | DC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CPL B 1709 |
| Chain | Residue |
| B | CPL1696 |
| B | CPL1699 |
| site_id | EC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CPL B 1710 |
| Chain | Residue |
| B | CPL1701 |
| B | CPL1712 |
| site_id | EC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CPL B 1711 |
| Chain | Residue |
| B | CPL1705 |
| B | CPL1707 |
| site_id | EC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CPL B 1712 |
| Chain | Residue |
| B | CPL1701 |
| B | CPL1710 |
| B | CPL1714 |
| site_id | EC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CPL A 1715 |
| Chain | Residue |
| A | CPL1703 |
| site_id | EC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CPL A 1716 |
| Chain | Residue |
| A | CPL1702 |
| A | CPL1708 |
| A | CPL1711 |
| A | CPL3077 |
| site_id | EC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CPL A 1717 |
| Chain | Residue |
| A | CPL1702 |
| A | CPL1713 |
| site_id | EC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CPL A 1718 |
| Chain | Residue |
| A | CPL3097 |
| B | CPL1704 |
| site_id | EC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CPL B 1714 |
| Chain | Residue |
| B | CPL1696 |
| B | CPL1697 |
| B | CPL1712 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 104 |
| Details | Intramembrane: {"evidences":[{"source":"PubMed","id":"17122778","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"20064379","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 236 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Region: {"description":"G1 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Region: {"description":"G3 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Region: {"description":"G4 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Region: {"description":"G5 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 68 |
| Details | Region: {"description":"Paddle domain","evidences":[{"source":"PubMed","id":"17122778","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"20064379","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 172 |
| Details | Region: {"description":"GED","evidences":[{"source":"PubMed","id":"17122778","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"20064379","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 116 |
| Details | Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17122778","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2J68","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
