Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CD A 1587 |
Chain | Residue |
A | HIS-5 |
A | HIS-3 |
A | CYS515 |
A | CL1588 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL A 1588 |
Chain | Residue |
A | HIS-5 |
A | HIS-4 |
A | HIS-3 |
A | CD1587 |
site_id | AC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CD A 1589 |
Chain | Residue |
A | HIS-4 |
B | GLU474 |
F | HIS500 |
A | HIS-2 |
site_id | AC4 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE CL A 1590 |
Chain | Residue |
A | SER514 |
A | CYS515 |
site_id | AC5 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CD A 1591 |
Chain | Residue |
B | CYS472 |
B | MET477 |
B | CL1587 |
site_id | AC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL A 1592 |
Chain | Residue |
A | HIS-6 |
A | HOH2007 |
B | CYS472 |
site_id | AC7 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE CL B 1587 |
Chain | Residue |
A | CD1591 |
B | LYS446 |
site_id | AC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CD B 1588 |
Chain | Residue |
B | HIS-5 |
B | HIS-3 |
B | CYS515 |
B | CL1589 |
site_id | AC9 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL B 1589 |
Chain | Residue |
B | HIS-3 |
B | HIS-4 |
B | CD1588 |
C | HIS500 |
site_id | BC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CD B 1590 |
Chain | Residue |
A | GLU474 |
B | HIS-4 |
B | HIS-2 |
C | HIS500 |
site_id | BC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL B 1591 |
Chain | Residue |
A | CYS472 |
A | CD1593 |
A | HOH2031 |
B | HIS-6 |
site_id | BC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CD A 1593 |
Chain | Residue |
A | CYS472 |
A | CL1594 |
A | HOH2021 |
B | HIS-6 |
B | LYS-7 |
B | CL1591 |
site_id | BC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL A 1594 |
Chain | Residue |
A | CYS472 |
A | MET477 |
A | CD1593 |
A | HOH2021 |
site_id | BC5 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL B 1592 |
Chain | Residue |
B | SER514 |
B | CYS515 |
B | HOH2039 |
site_id | BC6 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CD C 1587 |
Chain | Residue |
C | HIS-4 |
C | HIS-2 |
D | GLU474 |
E | HIS500 |
site_id | BC7 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL C 1588 |
Chain | Residue |
C | HIS-5 |
C | HIS-4 |
C | HIS-3 |
C | CD1589 |
site_id | BC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CD C 1589 |
Chain | Residue |
C | HIS-3 |
C | HIS-5 |
C | CYS515 |
C | CL1588 |
site_id | BC9 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE CL C 1590 |
Chain | Residue |
C | SER514 |
C | CYS515 |
site_id | CC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CL C 1591 |
Chain | Residue |
C | HIS-6 |
C | CD1592 |
C | HOH2005 |
D | CYS472 |
D | HOH2017 |
site_id | CC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CD C 1592 |
Chain | Residue |
C | HIS-6 |
C | CL1591 |
D | CYS472 |
D | CL1587 |
site_id | CC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL D 1587 |
Chain | Residue |
C | CD1592 |
D | VAL439 |
D | LYS446 |
D | CYS472 |
site_id | CC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL D 1588 |
Chain | Residue |
C | HOH2002 |
D | LYS433 |
D | PRO434 |
D | GLY435 |
site_id | CC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CD D 1589 |
Chain | Residue |
A | HIS500 |
C | GLU474 |
D | HIS-2 |
D | HIS-4 |
site_id | CC6 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE CL D 1590 |
Chain | Residue |
D | HIS-3 |
D | CD1591 |
site_id | CC7 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CD D 1591 |
Chain | Residue |
D | HIS-5 |
D | HIS-3 |
D | CYS515 |
D | CL1590 |
site_id | CC8 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL D 1592 |
Chain | Residue |
D | SER514 |
D | CYS515 |
D | HOH2010 |
site_id | CC9 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE CL C 1593 |
Chain | Residue |
C | LYS446 |
C | CD1594 |
site_id | DC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CD C 1594 |
Chain | Residue |
D | HIS-6 |
D | CL1593 |
C | CYS472 |
C | CL1593 |
site_id | DC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL D 1593 |
Chain | Residue |
C | CYS472 |
C | CD1594 |
D | HIS-6 |
D | HOH2006 |
site_id | DC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL C 1595 |
Chain | Residue |
C | LYS433 |
C | PRO434 |
C | GLY435 |
D | HOH2002 |
site_id | DC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CD E 1587 |
Chain | Residue |
B | HIS500 |
E | HIS-2 |
E | HIS-4 |
F | GLU474 |
site_id | DC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL E 1588 |
Chain | Residue |
B | HIS500 |
E | HIS-3 |
E | HIS-4 |
E | CD1590 |
site_id | DC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL E 1589 |
Chain | Residue |
C | HOH2046 |
E | SER514 |
E | CYS515 |
site_id | DC7 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CD E 1590 |
Chain | Residue |
E | HIS-3 |
E | HIS-5 |
E | CYS515 |
E | CL1588 |
site_id | DC8 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CL E 1591 |
Chain | Residue |
E | HIS-6 |
E | CD1592 |
E | HOH2006 |
F | CYS472 |
F | HOH2020 |
site_id | DC9 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CD E 1592 |
Chain | Residue |
E | HIS-6 |
E | CL1591 |
F | CYS472 |
F | CL1587 |
F | HOH2013 |
site_id | EC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CL F 1587 |
Chain | Residue |
E | CD1592 |
F | CYS472 |
F | MET477 |
F | HOH2013 |
F | HOH2026 |
site_id | EC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL F 1588 |
Chain | Residue |
E | HOH2003 |
F | LYS433 |
F | PRO434 |
F | GLY435 |
site_id | EC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL F 1589 |
Chain | Residue |
D | HIS500 |
F | HIS-4 |
F | HIS-3 |
F | CD1592 |
site_id | EC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CD F 1590 |
Chain | Residue |
D | HIS500 |
E | GLU474 |
F | HIS-2 |
F | HIS-4 |
site_id | EC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL F 1591 |
Chain | Residue |
E | CYS472 |
E | MET477 |
E | HOH2010 |
F | CD1594 |
site_id | EC6 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CD F 1592 |
Chain | Residue |
F | HIS-3 |
F | HIS-5 |
F | CYS515 |
F | CL1589 |
site_id | EC7 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL F 1593 |
Chain | Residue |
E | CYS472 |
E | HOH2016 |
F | HIS-6 |
F | CD1594 |
site_id | EC8 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CD F 1594 |
Chain | Residue |
E | CYS472 |
E | HOH2010 |
F | HIS-6 |
F | LYS-7 |
F | CL1591 |
F | CL1593 |
site_id | EC9 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL F 1595 |
Chain | Residue |
D | HOH2028 |
F | SER514 |
F | CYS515 |
F | HOH2044 |
site_id | FC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL E 1593 |
Chain | Residue |
E | LYS433 |
E | PRO434 |
E | GLY435 |
F | HOH2003 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 18 |
Details | ACT_SITE: Charge relay system; for serine protease activity => ECO:0000250 |
Chain | Residue | Details |
A | HIS461 | |
D | HIS461 | |
D | ASP489 | |
D | SER551 | |
E | HIS461 | |
E | ASP489 | |
E | SER551 | |
F | HIS461 | |
F | ASP489 | |
F | SER551 | |
A | ASP489 | |
A | SER551 | |
B | HIS461 | |
B | ASP489 | |
B | SER551 | |
C | HIS461 | |
C | ASP489 | |
C | SER551 | |