2VZ5
Structure of the PDZ domain of Tax1 (human T-cell leukemia virus type I) binding protein 3
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001650 | cellular_component | fibrillar center |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0007266 | biological_process | Rho protein signal transduction |
| A | 0008013 | molecular_function | beta-catenin binding |
| A | 0009966 | biological_process | regulation of signal transduction |
| A | 0016055 | biological_process | Wnt signaling pathway |
| A | 0030178 | biological_process | negative regulation of Wnt signaling pathway |
| A | 0032489 | biological_process | regulation of Cdc42 protein signal transduction |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 2000009 | biological_process | negative regulation of protein localization to cell surface |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IMD A 1129 |
| Chain | Residue |
| A | GLU62 |
| A | GLU67 |
| A | IMD1130 |
| A | ZN1131 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE IMD A 1130 |
| Chain | Residue |
| A | ZN1131 |
| A | GLU62 |
| A | GLU67 |
| A | ILE68 |
| A | ASP84 |
| A | IMD1129 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1131 |
| Chain | Residue |
| A | GLU62 |
| A | GLU67 |
| A | IMD1129 |
| A | IMD1130 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN A 1132 |
| Chain | Residue |
| A | HIS19 |
| A | GLU48 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 1133 |
| Chain | Residue |
| A | HIS90 |
| A | HIS90 |
| A | HOH2024 |
| A | HOH2024 |
| A | HOH2081 |
| A | HOH2081 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 97 |
| Details | Domain: {"description":"PDZ","evidences":[{"source":"PROSITE-ProRule","id":"PRU00143","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
