2VZ5

Structure of the PDZ domain of Tax1 (human T-cell leukemia virus type I) binding protein 3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001650	cellular_component	fibrillar center
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0007266	biological_process	Rho protein signal transduction
A	0008013	molecular_function	beta-catenin binding
A	0008285	biological_process	negative regulation of cell population proliferation
A	0015629	cellular_component	actin cytoskeleton
A	0016055	biological_process	Wnt signaling pathway
A	0030178	biological_process	negative regulation of Wnt signaling pathway
A	0043231	cellular_component	intracellular membrane-bounded organelle
A	0070062	cellular_component	extracellular exosome
A	0090630	biological_process	activation of GTPase activity
A	2000009	biological_process	negative regulation of protein localization to cell surface

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IMD A 1129

Chain	Residue
A	GLU62
A	GLU67
A	IMD1130
A	ZN1131

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE IMD A 1130

Chain	Residue
A	ZN1131
A	GLU62
A	GLU67
A	ILE68
A	ASP84
A	IMD1129

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 1131

Chain	Residue
A	GLU62
A	GLU67
A	IMD1129
A	IMD1130

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN A 1132

Chain	Residue
A	HIS19
A	GLU48

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site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL A 1133

Chain	Residue
A	HIS90
A	HIS90
A	HOH2024
A	HOH2024
A	HOH2081
A	HOH2081

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER61

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